PDBe 1p0m

X-ray diffraction
2.38Å resolution

Crystal structure of human butyryl cholinesterase in complex with a choline molecule

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cholinesterase Chain: A
Molecule details ›
Chain: A
Length: 529 amino acids
Theoretical weight: 59.71 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P06276 (Residues: 29-557; Coverage: 92%)
Gene names: BCHE, CHE1
Sequence domains: Carboxylesterase family
Structure domains: Rossmann fold

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: I422
Unit cell:
a: 154.657Å b: 154.657Å c: 128.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 0.244
Expression system: Cricetulus griseus