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Structure for family A2 unassigned peptidases

Summary Sequences Sequence features Distribution Structure Literature

 

PDB Organism Resolution Comment
1MVP avian myeloblastosis associated virus 2.20 Å mature
The dimer is shown. The active site residue Asp37 is shown in ball-and-stick representation in pink (one from each monomer).
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
avian myeloblastosis associated virus
mature  peptidase 2.20 Å 1MVP 1MVP 1MVP 1MVP 1MVP 1MVP Ohlendorf et al., 1992
theoretical model 0.00 Å 2MVP 2MVP 2MVP 2MVP 2MVP 2MVP
human immunodeficiency virus 1
mature  peptidase 2.00 Å 1BV7 1BV7 1BV7 1BV7 1BV7 1BV7 Ala et al., 1998
mature  peptidase 2.00 Å 1BV9 1BV9 1BV9 1BV9 1BV9 1BV9 Ala et al., 1998
mature  peptidase 0.00 Å 1BVE 1BVE 1BVE 1BVE 1BVE 1BVE Yamazaki et al., 1996
mature  peptidase 0.00 Å 1BVG 1BVG 1BVG 1BVG 1BVG 1BVG Yamazaki et al., 1996
mature  peptidase 1.90 Å 1BWA 1BWA 1BWA 1BWA 1BWA 1BWA Ala et al., 1998
mature  peptidase 1.80 Å 1BWB 1BWB 1BWB 1BWB 1BWB 1BWB Ala et al., 1998
mature  peptidase 2.70 Å 1C0T 1C0T 1C0T 1C0T 1C0T 1C0T Ren et al., 1999
mature  peptidase 2.52 Å 1C0U 1C0U 1C0U 1C0U 1C0U 1C0U Ren et al., 1999
mature  peptidase 2.50 Å 1C1B 1C1B 1C1B 1C1B 1C1B 1C1B Hopkins et al., 1999
mature  peptidase 2.50 Å 1C1C 1C1C 1C1C 1C1C 1C1C 1C1C Hopkins et al., 1999
mature  peptidase 2.00 Å 1DMP 1DMP 1DMP 1DMP 1DMP 1DMP Hodge et al., 1996
mature  peptidase 2.80 Å 1DTQ 1DTQ 1DTQ 1DTQ 1DTQ 1DTQ Ren et al., 2000
mature  peptidase 3.00 Å 1DTT 1DTT 1DTT 1DTT 1DTT 1DTT Ren et al., 2000
mature  peptidase 3.00 Å 1E6J 1E6J 1E6J 1E6J 1E6J 1E6J Monaco-Malbet et al., 2000
mature  peptidase 2.50 Å 1EP4 1EP4 1EP4 1EP4 1EP4 1EP4 Ren et al., 2000
mature  peptidase 0.00 Å 1ESK 1ESK 1ESK 1ESK 1ESK 1ESK
mature  peptidase 2.80 Å 1EX4 1EX4 1EX4 1EX4 1EX4 1EX4 Chen et al., 2000
mature  peptidase 1.60 Å 1EXQ 1EXQ 1EXQ 1EXQ 1EXQ 1EXQ Chen et al., 2000
Val48Gly, Met90Leu mutant; complex with saquinavir 2.60 Å 1FB7 1FB7 1FB7 1FB7 1FB7 1FB7 Hong et al., 2000
mature  peptidase 2.50 Å 1FK9 1FK9 1FK9 1FK9 1FK9 1FK9 Ren et al., 2000
mature  peptidase 2.90 Å 1FKO 1FKO 1FKO 1FKO 1FKO 1FKO Ren et al., 2000
mature  peptidase 2.90 Å 1FKP 1FKP 1FKP 1FKP 1FKP 1FKP Ren et al., 2000
mature  peptidase 1.90 Å 1G6L 1G6L 1G6L 1G6L 1G6L 1G6L Pillai et al., 2001
mature  peptidase 2.00 Å 1HIV 1HIV 1HIV 1HIV 1HIV 1HIV Thanki et al., 1992
mature  peptidase 1.80 Å 1HVH 1HVH 1HVH 1HVH 1HVH 1HVH Jadhav et al., 1998
mature  peptidase 1.80 Å 1HVR 1HVR 1HVR 1HVR 1HVR 1HVR Lam et al., 1994
mature  peptidase 1.80 Å 1HWR 1HWR 1HWR 1HWR 1HWR 1HWR Ala et al., 1998
mature  peptidase 2.30 Å 1HXB 1HXB 1HXB 1HXB 1HXB 1HXB Krohn et al., 1991
mature  peptidase 2.50 Å 1JKH 1JKH 1JKH 1JKH 1JKH 1JKH Ren et al., 2001
mature  peptidase 2.50 Å 1JLA 1JLA 1JLA 1JLA 1JLA 1JLA Ren et al., 2001
mature  peptidase 3.00 Å 1JLB 1JLB 1JLB 1JLB 1JLB 1JLB Ren et al., 2001
mature  peptidase 3.00 Å 1JLC 1JLC 1JLC 1JLC 1JLC 1JLC Ren et al., 2001
mature  peptidase 2.80 Å 1JLE 1JLE 1JLE 1JLE 1JLE 1JLE Ren et al., 2001
mature  peptidase 2.60 Å 1JLF 1JLF 1JLF 1JLF 1JLF 1JLF Ren et al., 2001
mature  peptidase 2.60 Å 1JLG 1JLG 1JLG 1JLG 1JLG 1JLG Ren et al., 2001
mature  peptidase 3.00 Å 1JLQ 1JLQ 1JLQ 1JLQ 1JLQ 1JLQ Chan et al., 2001
mature  peptidase 2.65 Å 1KLM 1KLM 1KLM 1KLM 1KLM 1KLM Esnouf et al., 1997
mature  peptidase 2.10 Å 1LV1 1LV1 1LV1 1LV1 1LV1 1LV1 Kumar et al., 2002
mature  peptidase 2.80 Å 1LW0 1LW0 1LW0 1LW0 1LW0 1LW0 Chamberlain et al., 2002
mature  peptidase 3.00 Å 1LW2 1LW2 1LW2 1LW2 1LW2 1LW2 Chamberlain et al., 2002
mature  peptidase 2.62 Å 1LWC 1LWC 1LWC 1LWC 1LWC 1LWC Chamberlain et al., 2002
mature  peptidase 2.81 Å 1LWE 1LWE 1LWE 1LWE 1LWE 1LWE Chamberlain et al., 2002
mature  peptidase 2.80 Å 1LWF 1LWF 1LWF 1LWF 1LWF 1LWF Chamberlain et al., 2002
mature  peptidase 0.00 Å 1NCP 1NCP 1NCP 1NCP 1NCP 1NCP Omichinski et al., 1991
mature  peptidase 0.00 Å 1O1W 1O1W 1O1W 1O1W 1O1W 1O1W Pari et al., 2003
mature  peptidase 2.10 Å 1ODW 1ODW 1ODW 1ODW 1ODW 1ODW
complex with inhibitor LP-130 2.00 Å 1ODY 1ODY 1ODY 1ODY 1ODY 1ODY Kervinen et al., 1998
mature  peptidase 1.80 Å 1QBR 1QBR 1QBR 1QBR 1QBR 1QBR Jadhav et al., 1997
mature  peptidase 1.80 Å 1QBS 1QBS 1QBS 1QBS 1QBS 1QBS Lam et al., 1996
mature  peptidase 2.10 Å 1QBT 1QBT 1QBT 1QBT 1QBT 1QBT Jadhav et al., 1997
mature  peptidase 1.80 Å 1QBU 1QBU 1QBU 1QBU 1QBU 1QBU Jadhav et al., 1997
mature  peptidase 2.60 Å 1REV 1REV 1REV 1REV 1REV 1REV Ren et al., 1995
mature  peptidase 2.55 Å 1RT1 1RT1 1RT1 1RT1 1RT1 1RT1 Hopkins et al., 1996
mature  peptidase 2.55 Å 1RT2 1RT2 1RT2 1RT2 1RT2 1RT2 Hopkins et al., 1996
mature  peptidase 3.00 Å 1RT3 1RT3 1RT3 1RT3 1RT3 1RT3 Ren et al., 1998
mature  peptidase 2.90 Å 1RT4 1RT4 1RT4 1RT4 1RT4 1RT4 Ren et al., 1998
mature  peptidase 2.90 Å 1RT5 1RT5 1RT5 1RT5 1RT5 1RT5 Ren et al., 1998
mature  peptidase 2.80 Å 1RT6 1RT6 1RT6 1RT6 1RT6 1RT6 Ren et al., 1998
mature  peptidase 3.00 Å 1RT7 1RT7 1RT7 1RT7 1RT7 1RT7 Ren et al., 1998
mature  peptidase 3.20 Å 1RTD 1RTD 1RTD 1RTD 1RTD 1RTD Huang et al., 1998
mature  peptidase 2.20 Å 1RTH 1RTH 1RTH 1RTH 1RTH 1RTH Ren et al., 1995
mature  peptidase 3.00 Å 1RTI 1RTI 1RTI 1RTI 1RTI 1RTI Ren et al., 1995
mature  peptidase 2.35 Å 1RTJ 1RTJ 1RTJ 1RTJ 1RTJ 1RTJ Esnouf et al., 1995
mature  peptidase 2.40 Å 1S1T 1S1T 1S1T 1S1T 1S1T 1S1T Ren et al., 2004
mature  peptidase 3.00 Å 1S1U 1S1U 1S1U 1S1U 1S1U 1S1U Ren et al., 2004
mature  peptidase 2.60 Å 1S1V 1S1V 1S1V 1S1V 1S1V 1S1V Ren et al., 2004
mature  peptidase 2.70 Å 1S1W 1S1W 1S1W 1S1W 1S1W 1S1W Ren et al., 2004
mature  peptidase 2.80 Å 1S1X 1S1X 1S1X 1S1X 1S1X 1S1X Ren et al., 2004
mature  peptidase 3.00 Å 1T05 1T05 1T05 1T05 1T05 1T05 Tuske et al., 2004
mature  peptidase 0.00 Å 1TAM 1TAM 1TAM 1TAM 1TAM 1TAM Matthews et al., 1995
mature  peptidase 2.60 Å 1TKT 1TKT 1TKT 1TKT 1TKT 1TKT Hopkins et al., 2004
mature  peptidase 2.85 Å 1TKX 1TKX 1TKX 1TKX 1TKX 1TKX Freeman et al., 2004
mature  peptidase 2.81 Å 1TKZ 1TKZ 1TKZ 1TKZ 1TKZ 1TKZ Hopkins et al., 2004
mature  peptidase 2.90 Å 1TL1 1TL1 1TL1 1TL1 1TL1 1TL1 Hopkins et al., 2004
mature  peptidase 2.80 Å 1TL3 1TL3 1TL3 1TL3 1TL3 1TL3 Hopkins et al., 2004
mature  peptidase 2.20 Å 1VRT 1VRT 1VRT 1VRT 1VRT 1VRT Ren et al., 1995
mature  peptidase 2.40 Å 1VRU 1VRU 1VRU 1VRU 1VRU 1VRU Ren et al., 1995
mature  peptidase 2.50 Å 2HND 2HND 2HND 2HND 2HND 2HND Ren et al., 2006
mature  peptidase 2.50 Å 2HNY 2HNY 2HNY 2HNY 2HNY 2HNY Ren et al., 2006
mature  peptidase 3.00 Å 2HNZ 2HNZ 2HNZ 2HNZ 2HNZ 2HNZ Ren et al., 2006
mature  peptidase 0.00 Å 2KOD 2KOD 2KOD 2KOD 2KOD 2KOD Byeon et al., 2009
mature  peptidase 1.65 Å 2NPH 2NPH 2NPH 2NPH 2NPH 2NPH Das et al., 2006
mature  peptidase 2.55 Å 2OPP 2OPP 2OPP 2OPP 2OPP 2OPP Ren et al., 2007
mature  peptidase 2.80 Å 2OPQ 2OPQ 2OPQ 2OPQ 2OPQ 2OPQ Ren et al., 2007
mature  peptidase 2.90 Å 2OPR 2OPR 2OPR 2OPR 2OPR 2OPR Ren et al., 2007
mature  peptidase 2.30 Å 2OPS 2OPS 2OPS 2OPS 2OPS 2OPS Ren et al., 2007
mature  peptidase 2.40 Å 2RF2 2RF2 2RF2 2RF2 2RF2 2RF2 Zhao et al., 2008
mature  peptidase 2.30 Å 2RKI 2RKI 2RKI 2RKI 2RKI 2RKI Kirschberg et al., 2008
mature  peptidase 1.69 Å 2WHH 2WHH 2WHH 2WHH 2WHH 2WHH Prashar et al., 2009
mature  peptidase 3.20 Å 2WOM 2WOM 2WOM 2WOM 2WOM 2WOM Corbau et al., 2010
mature  peptidase 2.80 Å 2WON 2WON 2WON 2WON 2WON 2WON Corbau et al., 2010
mature  peptidase 2.36 Å 2YNF 2YNF 2YNF 2YNF 2YNF 2YNF Chong et al., 2012
mature  peptidase 2.12 Å 2YNG 2YNG 2YNG 2YNG 2YNG 2YNG Chong et al., 2012
mature  peptidase 2.90 Å 2YNH 2YNH 2YNH 2YNH 2YNH 2YNH Chong et al., 2012
mature  peptidase 2.49 Å 2YNI 2YNI 2YNI 2YNI 2YNI 2YNI Chong et al., 2012
mature  peptidase 1.80 Å 3AO2 3AO2 3AO2 3AO2 3AO2 3AO2 Wielens et al., 2011
mature  peptidase 2.70 Å 3C6T 3C6T 3C6T 3C6T 3C6T 3C6T Tucker et al., 2008
mature  peptidase 2.70 Å 3C6U 3C6U 3C6U 3C6U 3C6U 3C6U Tucker et al., 2008
mature  peptidase 2.65 Å 3DI6 3DI6 3DI6 3DI6 3DI6 3DI6 Sweeney et al., 2008
mature  peptidase 2.50 Å 3DLE 3DLE 3DLE 3DLE 3DLE 3DLE Ren et al., 2008
mature  peptidase 2.20 Å 3DLG 3DLG 3DLG 3DLG 3DLG 3DLG Ren et al., 2008
mature  peptidase 3.10 Å 3DM2 3DM2 3DM2 3DM2 3DM2 3DM2 Ren et al., 2008
mature  peptidase 2.60 Å 3DMJ 3DMJ 3DMJ 3DMJ 3DMJ 3DMJ Ren et al., 2008
mature  peptidase 2.90 Å 3DOK 3DOK 3DOK 3DOK 3DOK 3DOK Ren et al., 2008
mature  peptidase 2.50 Å 3DOL 3DOL 3DOL 3DOL 3DOL 3DOL Ren et al., 2008
mature  peptidase 2.00 Å 3DOX 3DOX 3DOX 3DOX 3DOX 3DOX Bihani et al., 2009
mature  peptidase 2.60 Å 3DRP 3DRP 3DRP 3DRP 3DRP 3DRP Tucker et al., 2008
mature  peptidase 2.89 Å 3DRR 3DRR 3DRR 3DRR 3DRR 3DRR Tucker et al., 2008
mature  peptidase 3.15 Å 3DRS 3DRS 3DRS 3DRS 3DRS 3DRS Tucker et al., 2008
mature  peptidase 2.30 Å 3DYA 3DYA 3DYA 3DYA 3DYA 3DYA Sweeney et al., 2008
mature  peptidase 2.95 Å 3E01 3E01 3E01 3E01 3E01 3E01 Sweeney et al., 2008
mature  peptidase 2.60 Å 3FFI 3FFI 3FFI 3FFI 3FFI 3FFI
mature  peptidase 2.98 Å 3I0R 3I0R 3I0R 3I0R 3I0R 3I0R Su et al., 2009
mature  peptidase 2.70 Å 3I0S 3I0S 3I0S 3I0S 3I0S 3I0S Su et al., 2009
mature  peptidase 3.10 Å 3KJV 3KJV 3KJV 3KJV 3KJV 3KJV Lansdon et al., 2010
mature  peptidase 2.70 Å 3KK1 3KK1 3KK1 3KK1 3KK1 3KK1 Lansdon et al., 2010
mature  peptidase 2.90 Å 3KK2 3KK2 3KK2 3KK2 3KK2 3KK2 Lansdon et al., 2010
mature  peptidase 2.90 Å 3KK3 3KK3 3KK3 3KK3 3KK3 3KK3 Lansdon et al., 2010
mature  peptidase 1.65 Å 3KT2 3KT2 3KT2 3KT2 3KT2 3KT2 Bihani et al., 2009
mature  peptidase 1.80 Å 3KT5 3KT5 3KT5 3KT5 3KT5 3KT5 Bihani et al., 2009
mature  peptidase 2.30 Å 3LAK 3LAK 3LAK 3LAK 3LAK 3LAK Mitchell et al., 2010
mature  peptidase 2.51 Å 3LAL 3LAL 3LAL 3LAL 3LAL 3LAL Mitchell et al., 2010
mature  peptidase 2.76 Å 3LAM 3LAM 3LAM 3LAM 3LAM 3LAM Mitchell et al., 2010
mature  peptidase 2.55 Å 3LAN 3LAN 3LAN 3LAN 3LAN 3LAN Mitchell et al., 2010
mature  peptidase 2.79 Å 3LP0 3LP0 3LP0 3LP0 3LP0 3LP0 Su et al., 2010
mature  peptidase 2.23 Å 3LP1 3LP1 3LP1 3LP1 3LP1 3LP1 Su et al., 2010
mature  peptidase 2.80 Å 3LP2 3LP2 3LP2 3LP2 3LP2 3LP2 Su et al., 2010
mature  peptidase 2.67 Å 3M8P 3M8P 3M8P 3M8P 3M8P 3M8P Kertesz et al., 2010
mature  peptidase 2.70 Å 3M8Q 3M8Q 3M8Q 3M8Q 3M8Q 3M8Q Kertesz et al., 2010
mature  peptidase 2.30 Å 3MEC 3MEC 3MEC 3MEC 3MEC 3MEC Lansdon et al., 2010
mature  peptidase 2.50 Å 3MED 3MED 3MED 3MED 3MED 3MED Lansdon et al., 2010
mature  peptidase 2.40 Å 3MEE 3MEE 3MEE 3MEE 3MEE 3MEE Lansdon et al., 2010
mature  peptidase 2.80 Å 3MEG 3MEG 3MEG 3MEG 3MEG 3MEG Lansdon et al., 2010
mature  peptidase 1.76 Å 3MIM 3MIM 3MIM 3MIM 3MIM 3MIM Das et al., 2010
mature  peptidase 2.50 Å 3N3I 3N3I 3N3I 3N3I 3N3I 3N3I Prashar et al., 2010
mature  peptidase 2.95 Å 3NBP 3NBP 3NBP 3NBP 3NBP 3NBP Kertesz et al., 2010
mature  peptidase 2.70 Å 3PHV 3PHV 3PHV 3PHV 3PHV 3PHV Lapatto et al., 1989
mature  peptidase 1.70 Å 3QIN 3QIN 3QIN 3QIN 3QIN 3QIN Lansdon et al., 2011
mature  peptidase 1.40 Å 3QIO 3QIO 3QIO 3QIO 3QIO 3QIO Lansdon et al., 2011
mature  peptidase 2.09 Å 3QIP 3QIP 3QIP 3QIP 3QIP 3QIP Lansdon et al., 2011
mature  peptidase 2.60 Å 3T19 3T19 3T19 3T19 3T19 3T19 Gomez et al., 2011
mature  peptidase 2.40 Å 3T1A 3T1A 3T1A 3T1A 3T1A 3T1A Gomez et al., 2011
mature  peptidase 2.51 Å 3TAM 3TAM 3TAM 3TAM 3TAM 3TAM Gomez et al., 2011
mature  peptidase 3.30 Å 4B3O 4B3O 4B3O 4B3O 4B3O 4B3O Lapkouski et al., 2013
mature  peptidase 4.84 Å 4B3P 4B3P 4B3P 4B3P 4B3P 4B3P Lapkouski et al., 2013
mature  peptidase 5.00 Å 4B3Q 4B3Q 4B3Q 4B3Q 4B3Q 4B3Q Lapkouski et al., 2013
mature  peptidase 2.50 Å 4I7F 4I7F 4I7F 4I7F 4I7F 4I7F Parrish et al., 2013
mature  peptidase 2.68 Å 4KSE 4KSE 4KSE 4KSE 4KSE 4KSE Zheng et al., 2014
mature  peptidase 2.30 Å 4KV8 4KV8 4KV8 4KV8 4KV8 4KV8 LaPlante et al., 2013
mature  peptidase 2.58 Å 4NCG 4NCG 4NCG 4NCG 4NCG 4NCG Cote et al., 2014
mature  peptidase 1.85 Å 4Q1W 4Q1W 4Q1W 4Q1W 4Q1W 4Q1W Ragland et al., 2014
mature  peptidase 1.90 Å 4Q1X 4Q1X 4Q1X 4Q1X 4Q1X 4Q1X Ragland et al., 2014
mature  peptidase 1.50 Å 4Q1Y 4Q1Y 4Q1Y 4Q1Y 4Q1Y 4Q1Y Ragland et al., 2014
mature  peptidase 1.79 Å 4Q5M 4Q5M 4Q5M 4Q5M 4Q5M 4Q5M Prashar et al., 2015
mature  peptidase 2.45 Å 4QLH 4QLH 4QLH 4QLH 4QLH 4QLH
mature  peptidase 1.59 Å 4U1H 4U1H 4U1H 4U1H 4U1H 4U1H Kloverpris et al., 2015
mature  peptidase 1.92 Å 4U1I 4U1I 4U1I 4U1I 4U1I 4U1I Kloverpris et al., 2015
mature  peptidase 1.38 Å 4U1J 4U1J 4U1J 4U1J 4U1J 4U1J Kloverpris et al., 2015
mature  peptidase 1.70 Å 4U7Q 4U7Q 4U7Q 4U7Q 4U7Q 4U7Q Schimer et al., 2015
mature  peptidase 1.38 Å 4U7V 4U7V 4U7V 4U7V 4U7V 4U7V Schimer et al., 2015
x-ray snapshot of hiv-1 protease in action: observation of tetrahedralintermediate and its sihb with catalytic aspartate 1.76 Å 5YRS 5YRS 5YRS 5YRS 5YRS 5YRS

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