PDBe 1e6j

X-ray diffraction
3Å resolution

Crystal structure of HIV-1 capsid protein (p24) in complex with Fab13B5

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Igh protein Chain: H
Molecule details ›
Chain: H
Length: 219 amino acids
Theoretical weight: 23.55 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q99LC4 (Residues: 20-238; Coverage: 49%)
Gene name: Igh
Sequence domains:
Structure domains: Immunoglobulins
IMMUNOGLOBULIN Chain: L
Molecule details ›
Chain: L
Length: 210 amino acids
Theoretical weight: 23.05 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Gag protein Chain: P
Molecule details ›
Chain: P
Length: 210 amino acids
Theoretical weight: 23.42 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli
UniProt:
  • Canonical: H9A150 (Residues: 11-220; Coverage: 86%)
Gene name: gag
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: C2
Unit cell:
a: 193.08Å b: 45.6Å c: 132.47Å
α: 90° β: 132.41° γ: 90°
R-values:
R R work R free
0.21 0.21 0.284
Expression system: Escherichia coli