Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P62988

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
6	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
7	matrix metallopeptidase-2	6-27	N		MS	Schilling & Overall, 2008
11	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
16	glutamyl endopeptidase I	11-27	N		MS	Schilling & Overall, 2008
25	matrix metallopeptidase-2	24-43	N		MS	Schilling & Overall, 2008
27	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
33	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
42	matrix metallopeptidase-2	39-51	N		MS	Schilling & Overall, 2008
42	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
43	chymotrypsin A (cattle-type)	1-76	N		MS	Schilling & Overall, 2008
45	chymotrypsin A (cattle-type)	1-76	N		MS	Schilling & Overall, 2008
51	glutamyl endopeptidase I	1-76	N		MS	Schilling & Overall, 2008
54	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
54	thrombin	52-64	N		MS	Schilling & Overall, 2008
63	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
64	glutamyl endopeptidase I	1-76	N		MS	Schilling & Overall, 2008
76	ubiquitinyl hydrolase-YUH1	1-76	N			Liu et al., 1989
76	ubiquitinyl hydrolase-BAP1	1-76	N			Misaghi et al., 2009
76	ubiquitinyl hydrolase UCH-D	1-76	N			Layfield et al., 1999
76	ubiquitin-specific peptidase 5	1-76	N			Wilkinson, 1998
76	Ubp1 ubiquitin peptidase	1-76	N			Layfield et al., 1999
76	Ubp2 ubiquitin peptidase	1-76	N			Layfield et al., 1999
76	Ubp3 ubiquitin peptidase	1-76	N			Layfield et al., 1999
76	Doa4 ubiquitin peptidase	1-76	N			Amerik & Hochstrasser, 2004
76	ubiquitin-specific peptidase 4	1-76	N			Layfield et al., 1999
76	ubiquitin-specific peptidase 8	1-76	N			McCulloch et al., 2004
76	ubiquitin-specific peptidase 2	1-76	N			Baek et al., 1997
76	ubiquitin-specific peptidase 7	1-76	N			Layfield et al., 1999
76	ubiquitin-specific peptidase 15	1-76	P	release of a targetting peptide		Baker, 2004
76	ubiquitin-specific peptidase 9Y	1-76	N			Lee et al., 2003
76	ubiquitin-specific peptidase 36	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 42	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 46	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 37	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 38	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 44	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 35	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 30	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 45	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 51	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 34	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 49	1-76	N			Quesada et al., 2004
76	ubiquitin-specific peptidase 6 (Saccharomyces-type)	1-76	N			Park et al., 1997
76	putative ubiquitin carboxyl-terminal hydrolase ybl067c (Saccharomyces cerevisiae)	1-76	N			Layfield et al., 1999
76	YopJ protein	1-76	N			Zhou et al., 2005
76	CylD peptidase	1-76	N			Kovalenko et al., 2003
76	viral tegument protein deubiquitinylating peptidase	1-76	N			Kim et al., 2009
76	ElaD peptidase (Escherichia-type)	1-76	N			Rytkönen et al., 2007
76	OTU1 peptidase (Saccharomyces cerevisiae-type)	1-76	P			Ernst et al., 2009
76	ataxin-3 homologue (Caenorhabditis sp.)	1-76	N			Rodrigues et al., 2007
76	nairovirus deubiquitinylating peptidase	1-76	N			Frias-Staheli et al., 2007
76	STAMBP isopeptidase	1-76	N			McCulloch et al., 2004
76	unknown peptidase	1-76	N			Layfield et al., 1999