The cold-open state (OM, 4C), menthol-bound mouse TRPM8-I846V in complex with AITC and PIP2

Pseudomonas aeruginosa 50S ribosome (L1 stalk domain 'out' conformation)

PC94-A.15 Fab in complex with BG505 SOSIP trimer and RM20A3 Fab

PC94-A.16 Fab in complex with P94_v18_c046 Chimera DS-SOSIP trimer and RM20A3 Fab

Local refinement map of the RyR1-toxin complex using mask 1 (FKBP12.6/NTD/Nsol/SPRY/Repeat1&2)

Local map of the RyR1-toxin complex using mask 4 (TMD)

Consensus map of RyR-toxin complex

PC94-A.30 Fab in complex with BG505 SOSIP trimer and RM20A3 Fab

Local refinement map of the RyR1-toxin complex using mask 2 (Jsol/CSol/BSol)

Composite map of the RyR1-toxin complex

Local map of the RyR1-toxin complex using mask 3 (BSol/Repeat34)

PC94-A.27 Fab in complex with P94_v18_c046 Chimera DS-SOSIP trimer and RM20A3 Fab

PC94-A.31 Fab in complex with BG505 SOSIP trimer and RM20A3 Fab

Cryo-EM structure of DNA polymerase Zeta with RNA:DNA hybrid and incoming dNTP

Menthol-and PIP2-bound mouse TRPM8 in a closed (C1M) state

Cryo-EM structure of alpha-synuclein filaments (singlet) from Parkinson's disease with A53T mutation in SNCA

Cryo-EM structure of alpha-synuclein filaments (doublet) from Parkinson's disease with A53T mutation in SNCA

Cryo-EM structure of alpha-synuclein filaments (singlet) from M83(+/+) mouse brains with A53T mutation

Cryo-EM structure of alpha-synuclein filaments (doublet) from M83(+/+) mouse brains with A53T mutation

Calcium Bound Connexin-46/50 in Amphipol

Cryo-EM structure of the human ZNFX1 tetramer

Serotonin-bound structure

Structure of SS-L2-I53-50NP

The consensus map of the human ZNFX1 tetramer

Structure of SS-L2-LuSNP

Structure of SS-L2-FerritinNP

Focused Cryo-EM map of a half-region of the human ZNFX1 tetramer

Structure of Mosaic -5 IDD NPs

BRAF/CRAF/14-3-3 complex

Cryo-EM structure of Sr01-080, a denovo designed borneol dehydrogenase

The consensus EM map of human ZNFX1 dimer in complex with ssRNA and ATPgS

Cryo-EM structure of human ZNFX1 dimer in complex with ssRNA and ATPgS

Focused Cryo-EM map of a half-region of the ZNFX1 dimer in complex with ssRNA and ATPgS

BRAF/CRAF/MEK1/14-3-3 complex

Focus map for catalytic domains A and B for cryo-EM structure of an intact human acetylcholinesterase (T-form) tetramer in complex with ColQ

Focus map (A and B chains) for cryo-EM structure of an intact human acetylcholinesterase (T-form) tetramer in complex with PRiMA

Histamine-bound structure

Focus map (C and D chains) for cryo-EM structure of an intact human acetylcholinesterase (T-form) tetramer in complex with PRiMA

Consensus map for cryo-EM structure of an intact human acetylcholinesterase (T-form) tetramer in complex with ColQ

Consensus map for cryo-EM structure of an intact human acetylcholinesterase (T-form) tetramer in complex with PRiMA

Focus map for tetramerization domain of cryo-EM structure of an intact human acetylcholinesterase (T-form) tetramer in complex with ColQ

Cryo-EM structure of GPCR-miniGo Protein complex

Cryo-EM structure of GPCR-miniGo Protein complex

Cryo-electron tomogram acquired on a cryo-FIB lamella of two adjacent NIH 3T3 cells.

Cryo-EM structure of GPCR-miniGo Protein complex

Mature MPMV E26A capsid hexamer structure from capsid-like particles

Mature MPMV capsid hexamer structure from capsid-like particles

Mature MPMV capsid pentamer structure from capsid-like particles

Mature MoMLV capsid hexamer structure from capsid-like particles

Mature MPMV E26A capsid pentamer structure from capsid-like particles

Cryo-EM structure of human TMEM45B with a bound GM3 (18:1;O2/24:1)

Mature MPMV capsid hexamer 3-fold interface from capsid-like particles

Cryo-EM structure of GPCR-miniGo Protein complex

Cryo-EM structure of GPCR-miniGo Protein complex

Cryo-EM structure of GPCR-miniGo Protein complex

In situ cryo-electron tomogram of phagophore expansion in Atg2-PM4 mutant S. cerevisiae #1

Mature MoMLV capsid pentamer structure from capsid-like particles

In situ cryo-electron tomogram of phagophore expansion in Atg2-PM4 mutant S. cerevisiae #3

In situ cryo-electron tomogram of phagophore expansion in Atg2-PM4 mutant S. cerevisiae #2

Mature MoMLV capsid hexamer 3-fold interface from capsid-like particles

In situ cryo-electron tomogram of macroautophagy phagophore expansion in S. cerevisiae #2

In situ cryo-electron tomogram of macroautophagy phagophore expansion in S. cerevisiae #1

BG505gp140SOSIP.T332N_Q653L collected on 300 kV TFS Krios.

BG505gp140SOSIP.T332N_Q653L collected on 100 kV Tundra with Falcon C detector

Cryo-EM map of VHH20 a-PLA2 in complex with Basic phospholipase A2 nigexine

TASK-2 L127N at pH 6.5

TASK-2 at pH 8.5 with 100 uM Bupivacaine

TASK-2 at pH 6.5 with 100 uM Bupivacaine

TASK-2 at pH 6.5

Ternary complex of translating ribosome, NAC and NatB

In situ structure of the trans-stromal PSII-LHCII dimer(TS dimer) from Oryza sativa

In situ structure of the trans-stromal PSII-LHCII dimer (focused on one PSII)

In situ structure of the trans-stromal PSII-LHCII dimer (Consensus map)

In situ structure of the trans-lumenal/trans-stromal PSII-LHCII trimer (focused on PSII copy 3)

In situ structure of the trans-lumenal/trans-stromal PSII-LHCII trimer (focused on copy 1)

In situ structure of the trans-lumenal/trans-stromal PSII-LHCII trimer (focused on PSII copy 2)

In situ structure of the trans-stromal PSII-LHCII dimer (focused on copy 2)

In situ structure of the trans-lumenal/trans-stromal PSII-LHCII trimer (Consensus)

Cryo-EM structure of GroEL on an epoxy-functionalized graphene grid

Cryo-EM structure of GroEL on a NHS(5K)-functionalized graphene grid

In situ structure of the mixed trans-lumenal/trans-stromal and side-by-side PSII-LHCII tetramer (TL-TS-SS tetramer) from Oryza sativa

Cryo-EM structure of GroEL on a NHS(1K)-functionalized graphene grid

In situ structure of the mixed trans-lumenal/trans-stromal and side-by-side PSII-LHCII tetramer (Focused on PSII copy 3)

In situ structure of the mixed trans-lumenal/trans-stromal and side-by-side PSII-LHCII tetramer (Focused on PSII copy 2)

In situ structure of the mixed trans-lumenal/trans-stromal and side-by-side PSII-LHCII tetramer (Consensus map)

In situ structure of the mixed trans-lumenal/trans-stromal and side-by-side PSII-LHCII tetramer (Focused on PSII copy 1)

In situ structure of the trans-lumenal/trans-stromal PSII-LHCII trimer (TL-TS trimer) from Oryza sativa

In situ structure of the mixed trans-lumenal/trans-stromal and side-by-side PSII-LHCII tetramer (Focused on PSII copy 4)

TASK-2 K245A at pH 6.5

Canine circovirus virus-like particle with DNA

Structure of a canine circovirus virus-like particle

Cryo-EM structure of the E. coli beta sliding clamp-Hda heterooctamer

Cryo-EM structure of the E. coli beta sliding clamp

Structure of native human leukocyte myeloperoxidase

Cryo-EM structure of the E. coli beta sliding clamp-Hda heterohexamer

Cryo-EM structure of the E. coli beta sliding clamp-Hda heterotrimer

human VMAT2 in complex with AMPH

human VMAT2 in complex with lobeline

human VMAT2 in complex with MDMA

human VMAT2 in complex with METH

human VMAT2 in complex with MDA

Sunflower protein amyloid fibrils - PM2

Structure of the young Killifish Ribosome (head focus-refined with partial mask)

Structure of the old Killifish Ribosome (head focus-refined)

Structure of the young Killifish Ribosome (Consensus map)

Structure of the young Killifish Ribosome (small subunit focus-refined)

Structure of the old Killifish Ribosome (Composite map)

Structure of the old Killifish Ribosome (Consensus map)

CRYO-EM FOCUSED REFINEMENT MAP OF TRYPANOSOMA BRUCEI BLOODSTREAM FORM 80S RIBOSOME

Structure of the old Killifish Ribosome (head focus-refined with partial mask)

Structure of the young Killifish Ribosome (head focus-refined)

Structure of the old Killifish Ribosome (Small subunit focus-refined)

Structure of the old Killifish Proteasome

CRYO-EM STRUCTURE OF TRYPANOSOMA BRUCEI BLOODSTREAM FORM 80S RIBOSOME

CRYO-EM CONSENSUS MAP OF TRYPANOSOMA BRUCEI BLOODSTREAM FORM 80S RIBOSOME

Structure of the young Killifish Ribosome (Composite map)

Cryo-EM density map of essential Mycoplasma pneumoniae lipoprotein Mpn436 at 3.65 A

Structure of SAM bound cis-basal CBS conformer - by helical approach

Cryo-EM consensus map (unfocused) of essential Mycoplasma pneumoniae lipoprotein Mpn436 at 3.65 A

Cryo-EM focused map of essential Mycoplasma pneumoniae lipoprotein Mpn444 tip region at 4.07 A

Cryo-EM density map of essential Mycoplasma pneumoniae lipoprotein Mpn444 at 3.74 A

Cryo-EM structure of Arabidopsis VIM1 in complex with hemi-methylated CG-containing nucleosome 2

Cryo-EM structure of Arabidopsis VIM1 in complex with hemi-methylated CG-containing nucleosome 2

Cryo-EM structure of Arabidopsis VIM1 in complex with hemi-methylated CG-containing nucleosome 1

Cryo-EM structure of Arabidopsis VIM1 in complex with hemi-methylated CG-containing nucleosome 2

Cryo-EM structure of Arabidopsis VIM1 in complex with hemi-methylated CG-containing nucleosome and UBC11

Cryo-EM structure of Arabidopsis VIM1 in complex with hemi-methylated CG-containing nucleosome 1

Cryo-EM structure of Arabidopsis VIM1 in complex with hemi-methylated CG-containing nucleosome 1

Cryo-electron tomogram of cyanobacteria Prochlorococcus MED4

Phosphorylated STING bound to adaptor protein complex 1 (processed for improved pSTING density)

Structure of B10 anti-stem antibody in complex with ZEBOV spike complex

Cryo-EM structure of bacteriophage A1002 neck-collar

In situ structure of the ETF-BCR complex from Geobacter metallireducens

Cryo-electron tomogram of Geobacter metallireducens, dataset Geo02, Position 11_2

Cryo-electron tomogram of Geobacter metallireducens, dataset Geo02, Position 1_2

In situ structure of the 70S ribosome from Geobacter metallireducens

DIT3 nanofibril

Cryo-electron tomogram of Geobacter metallireducens, dataset Geo02, Position 11

In situ structure of the class II BCR from Geobacter metallireducens

In situ structure of the 100S disome from Geobacter metallireducens

CryoEM map of the tail part of the Plastid-Encoded RNA Polymerase from Chlamydomonas reinhardtii

Cryo-electron tomogram of Geobacter metallireducens, dataset Geo02, Position 1

Cryo-electron tomogram of Geobacter metallireducens, dataset Geo02, Position 1_3

Cryo-EM single particle structure of the Plastid-Encoded RNA Polymerase (PEP)from Chlamydomonas reinhardtii.

Cryo-EM structure of Plastid-Encoded RNA Polymerase from Chlamydomonas reinhardtii - core part refined

S. aureus DNA Gyrase in complex with OSUAB-0284 and DNA

S. aureus DNA Gyrase in complex with OSUAB-0276 and DNA

Mtb galactan transporter Rv3781/3783, translocating intermediate state

Mtb galactan transporter Rv3781/3783, open state

Mtb galactan transporter Rv3781/3783, ATP-bound

Cryo-EM structure of dimeric Nitrogenase MoFe protein from Methanosarcina acetivorans

Cryo-EM structure of Leishmania tarentolae respiratory complex III (cytochrome bc1 complex)

Cryo-EM structure of Leishmania tarentolae respiratory complex V (ATP synthase) Fo monomer membrane region

Cryo-EM structure of Leishmania tarentolae respiratory complex V (ATP synthase) peripheral stalk

Leishmania tarentolae respiratory complex V (ATP synthase) F1/central-stalk

Leishmania tarentolae respiratory complex V (ATP synthase) dimer

Cryo-EM structure of TccCas13a-crRNA-target RNA ternary complex

Cryo-EM structure of Leishmania tarentolae respiratory complex V (ATP synthase) membrane region

Cryo-EM structure of Leishmania tarentolae respiratory complex IV (cytochrome c oxidase dimer)

Salmonella Flagellar Export Apparatus (FliPQR/FlhB/FlhA) in the context of the intact basal body with an asymmetric FlhA ring

In situ structure of the bis-trans-lumenal/trans-stromal PSII-LHCII tetramer (TL-TS-TL tetramer) from Oryza sativa

Cryo-EM structure of Arabidopsis nucleosome

Cryo-EM structure of Arabidopsis H3-H4 octasome class1

Cryo-EM structure of Arabidopsis H3-H4 octasome class3

Cryo-EM structure of Arabidopsis H3-H4 octasome class5

Cryo-EM structure of Arabidopsis H3-H4 octasome class4

Cryo-EM structure of Arabidopsis H3-H4 octasome class2

Cryo-EM structure of Arabidopsis H3-H4 octasome

In situ structure of the bis-trans-lumenal/trans-stromal PSII-LHCII tetramer (TL-TS-TL tetramer) (focused on PSII copy 3)

In situ structure of the bis-trans-lumenal/trans-stromal PSII-LHCII tetramer (TL-TS-TL tetramer) (focused on PSII copy 2)

In situ structure of the trans-lumenal PSII-LHCII dimer from Oryza sativa (composite)

In situ structure of the trans-lumenal PSII-LHCII dimer (focused on PSII copy 2)

In situ structure of the bis-trans-lumenal/trans-stromal PSII-LHCII tetramer (TL-TS-TL tetramer) (focused on PSII copy 4)

In situ structure of the bis-trans-lumenal/trans-stromal PSII-LHCII tetramer (TL-TS-TL tetramer) (focused on PSII copy 1)

In situ structure of the trans-lumenal PSII-LHCII dimer (focused on PSII copy 1)

In situ C2S2M2L4-type PSII-LHCII supercomplex, core, protomer 1

Melbournevirus two-fold block (CryoSPARC processing with PASR)

Melbournevirus threefold block (CryoSPARC processed with PASR)

Melbournevirus fivefold block (CryoSPARC processed with PASR)

In situ C2S2M2L4-type PSII-LHCII supercomplex, moderately bound (M-) LHCII trimer with CP29 and CP24, protomer 1

In situ C2S2M2L4-type PSII-LHCII supercomplex, core, protomer 2

In situ C2S2M2L4-type PSII-LHCII supercomplex, strongly bound (S-) LHCII trimer with CP26, protomer 2

In situ C2S2M2L4-type PSII-LHCII supercomplex, strongly bound (S-) LHCII trimer with CP26, protomer 1

In situ C2S2M2L4-type PSII-LHCII supercomplex, moderately bound (M-) LHCII trimer with CP29 and CP24, protomer 2

Synaptotagmin-1_molecules_from_the_0_mM_Ca2_Cluster1

In situ structure of the C2S2M2L4-typePSII-LHCII superconplex from Oryza sativa (consensus)

E coli CNF1 in complex with BCAM receptor

EcPriA bound to DNA replication fork with ssDNA lagging strand (CRR up)

EcPriA bound to DNA replication fork with ssDNA lagging strand (CRR down)

Laminin 511 in complex with BCAM

Focused map (Catalytic Subunit) of the Strand-Displacement Complex of Human Mitochondrial DNA Polymerase Gamma

Raw Consensus map of the Strand-Displacement Complex of Human Mitochondrial DNA Polymerase Gamma

EcPriA bound to DNA replication fork with dsDNA lagging strand

Human DNA Polymerase Gamma-RNA-DNA Primer-Template Complex with Incoming ATP

Structure of a Strand-Displacement Complex of Human Mitochondrial DNA Polymerase Gamma

Ca2+ bound destabilized open state Connexin-46/50

Ca2+ bound gated state Connexin-46/50

Focused map (Accessory Subunit) of the Strand-Displacement Complex of Human Mitochondrial DNA Polymerase Gamma

Ra22QT77 RBD in complex with Bat ACE2

In situ structure of the C2S2M2L4-type PSII-LHCII supercomplex from Oryza sativa

YsaN monomer of 14-mer YsaN complex (Focus Refinement)

Cryo-EM Structure of the 14-Mer ATPase Complex YsaN from the Type III Secretion System of Yersinia enterocolitica

LEN-bound HIV-1 capsid lattice within intact VLPs

LEN-bound HIV-1 capsid lattice within VLPs treated with PFO, no symmetry

cryo-EM structure of l-SPD bound D1R-Gs complex

LEN-unbound HIV-1 capsid lattice within VLPs treated with PFO, no symmetry

LEN-unbound HIV-1 capsid lattice within VLPs treated with PFO, C6 symmetry

LEN-bound HIV-1 capsid lattice within VLPs treated with PFO, C6 symmetry

cryo-EM structure of l-SPD binding to D2R

CryoEM structure of a dNTPase from Vibrio cholerae in hexadecamericmform

Complex structure of BoNT-like PG1 at pH 6.0

Cryo-EM structure of spike protein within graphene reservoir sandwich

apo structure of P2X332

ATP-bound structure of P2X322

Tetrahymena Ribozyme scaffolded SicX sRNA in complex with C-di-GMP

ATP-bound structure of P2X332

AF219-bound structure of P2X332

2-fold region of mature T7 without defocus refinement

Icosahedral structure of mature T7

3-fold region of mature T7 without defocus refinement

Cryo-EM structure of AtSLAH3

Cryo-EM structure of AtSLAH3 S343V mutant

3f-fold region of mature T7 with defocus refinement

Portal-tail complex of mature T7 without defocus refinement

5f-fold region of mature T7 with defocus refinement

Cryo-EM structure of AtSLAH3 L400A mutant

5-fold region of mature T7 without defocus refinement

core protein structure of mature T7 without defocus refinement

2f-fold region of mature T7 with defocus refinement

Cryo-EM structure of AtSLAH3 7D/L400A mutant

Structure of the Vesicular Stomatitis Virus L Protein in Complex with the Phosphoprotein and the Nucleoprotein

T33-Fus-1B cage - Designed tetrahedral protein cage based on helical fusion and machine learning

MspA-M2 in a POPC nanodisc

Cryo-EM structure of the E. coli DRT10 RT-ncRNA complex, Eco3 subtype.

Cryo-EM structure of the E. coli DRT10 RT-ncRNA complex, Eco1 subtype

Cryo-EM structure of the E. coli DRT10 RT-ncRNA complex, Eco3 subtype with dNTPs

Core Mediator of PIC-Med-SWI/SNF-Nucleosome

Extra Med5/16 of PIC-Med-SWI/SNF

TBP/TFIIE/DNA of PIC-Med-SWI/SNF

ARP of SWI/SNF of PIC-Med-SWI/SNF-Nucleosome

Pseudomonas aeruginosa CdrA N*-terminal domain plus ~6 repeats of the extension domain

Pseudomonas aeruginosa CdrA N*-terminal domain

Core SWI/SNF of PIC-Med-SWI/SNF-Nucleosome

Menthol-bound mouse TRPM8 in complex with AITC and PIP2 in a closed (C1M') state

PolII/TFIIF of PIC-Med-SWI/SNF

Sunflower protein amyloid fibrils

The pre-open state (pre-OM, 20C), menthol-bound mouse TRPM8-I846V in complex with AITC and PIP2

Menthol-bound mouse TRPM8-I846V in complex with PIP2 in an intermediate (C2M, 20C) state

AITC- and PIP2-bound mouse TRPM8 in a closed (C1A) state

The cold-intermediate state (C2M, 4C), menthol-bound mouse TRPM8-I846V in complex with AITC and PIP2

Pseudomonas aeruginosa 50S ribosome (L1 stalk domain 'out' conformation and missing uL1 and tRNA)