EMD-75368

Single-particle
2.96 Å
EMD-75368
3D View Gallery
Deposition: 30/01/2026
Map released: 07/10/2026
Last modified: 07/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75368

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-10pc summary report (pdf.gz) Map-10pc FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

TASK-2 at pH 6.5 with 100 uM Bupivacaine

EMD-75368

Single-particle
2.96 Å
EMD-75368
3D View Gallery
Deposition: 30/01/2026
Map released: 07/10/2026
Last modified: 07/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: TASK-2 in MSP1D1 nanodisc
Fitted models: 10pc

Deposition Authors: Docter T, Li B, Brohawn SG

A shared site for lipid and anesthetic block of the two-pore domain K+ channel TASK-2
Docter T, Sorum B, Li B, Rietmeijer RA, Cook ASI, Kotecha A, Brohawn SG
To Be Published