EMD-55646

Single-particle
3.03 Å
EMD-55646
3D View Gallery
Deposition: 11/11/2025
Map released: 07/10/2026
Last modified: 07/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-55646

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of GPCR-miniGo Protein complex

EMD-55646

Single-particle
3.03 Å
EMD-55646
3D View Gallery
Deposition: 11/11/2025
Map released: 07/10/2026
Last modified: 07/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: GPCR-Go protein complex

Deposition Authors: Yardeni EH , Kiss DJ , Keseru GM , Shalev-Benami M
The structure of the dopamine D 3 receptor bound to cariprazine reveals principles for partial agonists with designed pharmacology.
Hadas Yardeni E , Kiss DJ , Sanchez J , Shavit K , Szepesi Kovacs D, Egyed A , Vogt CD, Gaitonde SA, Glenn J , Canals M , Bouvier M , Newman AH, Lane JR , Keseru GM , Shalev-Benami M
(2026) Sci Adv , 12 , eaef7411 - eaef7411
PUBMED: 42664351
DOI: doi:10.1126/sciadv.aef7411
ISSN: 2375-2548
Grant Support: