Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-47179

Helical reconstruction
3.4 Å
EMD-47179
3D View Gallery
Deposition: 04/10/2024
Map released: 23/10/2024
Last modified: 11/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-47179
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9duu summary report (pdf.gz) Map and 9duu FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of recombinant wildtype ACTA1 phalloidin-stabilized F-actin

EMD-47179

Helical reconstruction
3.4 Å
EMD-47179
3D View Gallery
Deposition: 04/10/2024
Map released: 23/10/2024
Last modified: 11/12/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Amanita phalloides
Sample: Cryo-EM structure of recombinant wildtype ACTA1 phalloidin-stabilized F-actin
Fitted models: 9duu

Deposition Authors: Garg A , Greenberg MJ , Zhang R
Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility.
Garg A , Jansen S , Greenberg L, Zhang R, Lavine KJ, Greenberg MJ
(2024) PNAS , 121 , e2405020121 - e2405020121
PUBMED: 39503885
DOI: doi:10.1073/pnas.2405020121
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: