Structure for peptidase S01.151: trypsin 1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
1JRS Bos taurus 1.80 Å complex with leupeptin
Catalytic residues are shown in ball-and-stick representation: His60 in purple, Asp104 in pink and Ser197 in orange. The structural calcium ion is shown as a yellow CPK sphere. Bound inhibitor is shown in grey in ball-and-stick representation.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Bos taurus
complex with aeruginosin 98-B inhibitor 2.20 Å 1AQ7 1AQ7 1AQ7 1AQ7 1AQ7 1AQ7
complex with metacyano benzylic inhibitor 2.10 Å 1AUJ 1AUJ 1AUJ 1AUJ 1AUJ 1AUJ Lee et al., 1997
complex with bis-phenylamidine inhibitor 1.80 Å 1AZ8 1AZ8 1AZ8 1AZ8 1AZ8 1AZ8
beta-trypsin; complex with ACPU 1.80 Å 1BJU 1BJU 1BJU 1BJU 1BJU 1BJU Presnell et al., 1998
beta-trypsin; complex with APPU 1.80 Å 1BJV 1BJV 1BJV 1BJV 1BJV 1BJV Presnell et al., 1998
mature  peptidase 2.20 Å 1BTP 1BTP 1BTP 1BTP 1BTP 1BTP Odagaki et al., 1995
complex with 1.80 Å 1BTW 1BTW 1BTW 1BTW 1BTW 1BTW
beta-trypsin; complex with T-butoxy-Ala-Val-boroLys ethyl ester 1.80 Å 1BTX 1BTX 1BTX 1BTX 1BTX 1BTX Katz et al., 1995
beta-trypsin; complex with benzyldiamine 1.50 Å 1BTY 1BTY 1BTY 1BTY 1BTY 1BTY Katz et al., 1995
beta-trypsin; complex with T-butoxy-Ala-Val-boroLys methyl ester 2.00 Å 1BTZ 1BTZ 1BTZ 1BTZ 1BTZ 1BTZ Katz et al., 1995
complex with benzamidine 1.40 Å 1C1N 1C1N 1C1N 1C1N 1C1N 1C1N Katz et al., 1998
mature  peptidase 1.40 Å 1C1O 1C1O 1C1O 1C1O 1C1O 1C1O Katz et al., 1998
complex with (5-amidino-2-benzimidazolyl) (2-benzimidazolyl)methane 1.37 Å 1C1P 1C1P 1C1P 1C1P 1C1P 1C1P Katz et al., 1998
complex with (5-amidino-2-benzimidazolyl) (2-benzimidazolyl)methane 1.37 Å 1C1Q 1C1Q 1C1Q 1C1Q 1C1Q 1C1Q Katz et al., 1998
complex with (5-amidino-2-benzimidazolyl) (2-benzimidazolyl)methane 1.37 Å 1C1R 1C1R 1C1R 1C1R 1C1R 1C1R Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methane 1.63 Å 1C1S 1C1S 1C1S 1C1S 1C1S 1C1S Katz & Luong, 1999
complex with bis(5-amidino-2-benzimidazolyl)methane 1.37 Å 1C1T 1C1T 1C1T 1C1T 1C1T 1C1T Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methane ketone 1.65 Å 1C2D 1C2D 1C2D 1C2D 1C2D 1C2D Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methane ketone 1.65 Å 1C2E 1C2E 1C2E 1C2E 1C2E 1C2E Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methane ketone hydrate 1.70 Å 1C2F 1C2F 1C2F 1C2F 1C2F 1C2F Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methane ketone hydrate 1.65 Å 1C2G 1C2G 1C2G 1C2G 1C2G 1C2G Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methane ketone hydrate 1.40 Å 1C2H 1C2H 1C2H 1C2H 1C2H 1C2H Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methane ketone hydrate 1.47 Å 1C2I 1C2I 1C2I 1C2I 1C2I 1C2I Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methane ketone 1.40 Å 1C2J 1C2J 1C2J 1C2J 1C2J 1C2J Katz et al., 1998
complex with 5-amidino-benzimidazole 1.65 Å 1C2K 1C2K 1C2K 1C2K 1C2K 1C2K Katz et al., 1998
mature  peptidase 1.50 Å 1C2L 1C2L 1C2L 1C2L 1C2L 1C2L Katz et al., 1998
mature  peptidase 1.40 Å 1C2M 1C2M 1C2M 1C2M 1C2M 1C2M Katz et al., 1998
complex with benzamidine 1.43 Å 1C5P 1C5P 1C5P 1C5P 1C5P 1C5P Katz et al., 2000
complex with 4-iodobenzo[B]thiophene-2-carboxamidine 1.43 Å 1C5Q 1C5Q 1C5Q 1C5Q 1C5Q 1C5Q Katz et al., 2000
complex with 4-iodobenzo[B]thiophene-2-carboxamidine 1.47 Å 1C5R 1C5R 1C5R 1C5R 1C5R 1C5R Katz et al., 2000
complex with 4-iodobenzo[B]thiophene-2-carboxamidine 1.36 Å 1C5S 1C5S 1C5S 1C5S 1C5S 1C5S Katz et al., 2000
complex with thieno[2,3-B]pyridine-2-carboxamidine 1.37 Å 1C5T 1C5T 1C5T 1C5T 1C5T 1C5T Katz et al., 2000
complex with thieno[2,3-B]pyridine-2-carboxamidine 1.37 Å 1C5U 1C5U 1C5U 1C5U 1C5U 1C5U Katz et al., 2000
mature  peptidase 1.48 Å 1C5V 1C5V 1C5V 1C5V 1C5V 1C5V Katz et al., 2000
complex with bdellastasin 3.30 Å 1C9T 1C9T 1C9T 1C9T 1C9T 1C9T Rester et al., 1999
beta-trypsin; complex with benzamidine 1.90 Å 1CE5 1CE5 1CE5 1CE5 1CE5 1CE5 Ota et al., 1999
NMR structure; complex with 2-[3-amino(imino)methyl phenoxy]-6-[2-(aminomethyl)phenoxy]-3,5-difluoro-4-methylpyridine 0.00 Å 1CU7 1CU7 1CU7 1CU7 1CU7 1CU7
NMR structure; complex with 2,6-bis[3-amino(imino)methyl phenoxy]-3,5-difluoro-4-methylpyridine 0.00 Å 1CU8 1CU8 1CU8 1CU8 1CU8 1CU8
NMR structure; complex with 2,6-bis[3-amino(imino)methyl phenoxy]-3,5-difluoro-4-methylpyridine (ZK-805623) 0.00 Å 1CU9 1CU9 1CU9 1CU9 1CU9 1CU9
complex with soyabean Bowman-Birk inhibitor 2.30 Å 1D6R 1D6R 1D6R 1D6R 1D6R 1D6R Koepke et al., 2000
complex with inhibitor BPO 2.00 Å 1EB2 1EB2 1EB2 1EB2 1EB2 1EB2 Liebeschuetz et al., 2002
complex with pancreatic trypsin inhibitor Ala16Leu mutant 1.85 Å 1EJM 1EJM 1EJM 1EJM 1EJM 1EJM Grzesiak et al., 2000
complex with alpha-1-proteinase inhibitor 2.60 Å 1EZX 1EZX 1EZX 1EZX 1EZX 1EZX Huntington et al., 2000
complex with RPR131247 inhibitor 1.80 Å 1F0T 1F0T 1F0T 1F0T 1F0T 1F0T Maignan et al., 2000
complex with RPR128515 inhibitor 1.90 Å 1F0U 1F0U 1F0U 1F0U 1F0U 1F0U Maignan et al., 2000
complex with MCTI-A inhibitor from bitter gourd 1.79 Å 1F2S 1F2S 1F2S 1F2S 1F2S 1F2S Zhu et al., 1999
complex with T87 inhibitor 1.90 Å 1G34 1G34 1G34 1G34 1G34 1G34 Nar et al., 2001
complex with R11 inhibitor 1.90 Å 1G36 1G36 1G36 1G36 1G36 1G36 Nar et al., 2001
bound to meta-amidino Schiff base magnesium(II) chelate 1.80 Å 1G3B 1G3B 1G3B 1G3B 1G3B 1G3B Toyota et al., 2001
bound to para-amidino Schiff base iron(III) chelate 1.80 Å 1G3C 1G3C 1G3C 1G3C 1G3C 1G3C Toyota et al., 2001
bound to meta-amidino Schiff base copper(II) chelate 1.80 Å 1G3D 1G3D 1G3D 1G3D 1G3D 1G3D Toyota et al., 2001
bound to para-amidino Schiff base copper(II) chelate 1.80 Å 1G3E 1G3E 1G3E 1G3E 1G3E 1G3E Toyota et al., 2001
complex with engineered mung bean inhibitor 2.20 Å 1G9I 1G9I 1G9I 1G9I 1G9I 1G9I Zhu et al., 2001
guanidinobenzoylated at Ser-195 2.00 Å 1GBT 1GBT 1GBT 1GBT 1GBT 1GBT Mangel et al., 1990
mature  peptidase 1.39 Å 1GHZ 1GHZ 1GHZ 1GHZ 1GHZ 1GHZ Katz et al., 2001
mature  peptidase 1.42 Å 1GI0 1GI0 1GI0 1GI0 1GI0 1GI0 Katz et al., 2001
mature  peptidase 1.42 Å 1GI1 1GI1 1GI1 1GI1 1GI1 1GI1 Katz et al., 2001
mature  peptidase 1.38 Å 1GI2 1GI2 1GI2 1GI2 1GI2 1GI2 Katz et al., 2001
mature  peptidase 1.44 Å 1GI3 1GI3 1GI3 1GI3 1GI3 1GI3 Katz et al., 2001
complex with 2-(2-hydroxy-phenyl)-3H-benzoimidazole-5-carboxamidine 1.37 Å 1GI4 1GI4 1GI4 1GI4 1GI4 1GI4 Katz et al., 2001
mature  peptidase 1.60 Å 1GI5 1GI5 1GI5 1GI5 1GI5 1GI5 Katz et al., 2001
mature  peptidase 1.49 Å 1GI6 1GI6 1GI6 1GI6 1GI6 1GI6 Katz et al., 2001
engineering inhibitors highly selective for the s1 sites of ser190 trypsin-like serine protease drug targets 1.50 Å 1GJ6 1GJ6 1GJ6 1GJ6 1GJ6 1GJ6 Katz et al., 2001
atomic resolution structures of trypsin provide insight into structural radiation damage 0.95 Å 1HJ9 1HJ9 1HJ9 1HJ9 1HJ9 1HJ9 Leiros et al., 2001
complex with benzamidine inhibitor 1.21 Å 1J8A 1J8A 1J8A 1J8A 1J8A 1J8A
complex with amylamine in cyclohexane 2.00 Å 1JIR 1JIR 1JIR 1JIR 1JIR 1JIR
complex with leupeptin 1.80 Å 1JRS 1JRS 1JRS 1JRS 1JRS 1JRS Kurinov & Harrison, 1996
complex with leupeptin 1.80 Å 1JRT 1JRT 1JRT 1JRT 1JRT 1JRT Kurinov & Harrison, 1996
complex with N-alpha-(2-naphthylsulfonyl)-N-(3-amidino-l-phenylalaninyl)-D-pipecolinic acid 2.20 Å 1K1I 1K1I 1K1I 1K1I 1K1I 1K1I Dullweber et al., 2001
bovine trypsin-inhibitor complex 2.20 Å 1K1J 1K1J 1K1J 1K1J 1K1J 1K1J Dullweber et al., 2001
complex with N-alpha-(2-naphthylsulfonyl)-3-amidino-l-phenylalanine piperazide 2.50 Å 1K1L 1K1L 1K1L 1K1L 1K1L 1K1L Dullweber et al., 2001
complex with N-alpha-(2-naphthylsulfonyl)-N(3-amidino-l-phenylalaninyl)-4-acetyl-piperazine 2.20 Å 1K1M 1K1M 1K1M 1K1M 1K1M 1K1M Dullweber et al., 2001
bovine trypsin-inhibitor complex 2.00 Å 1K1N 1K1N 1K1N 1K1N 1K1N 1K1N Dullweber et al., 2001
bovine trypsin-inhibitor complex 2.00 Å 1K1O 1K1O 1K1O 1K1O 1K1O 1K1O Dullweber et al., 2001
bovine trypsin-inhibitor complex 1.90 Å 1K1P 1K1P 1K1P 1K1P 1K1P 1K1P Dullweber et al., 2001
complex with [4-([5-benzyloxy-1-(3-carbamimidoyl-benzyl)-1H-indole-2-carbonyl]-amino-methyl)-phenyl]-trimethyl-ammonium 2.20 Å 1LQE 1LQE 1LQE 1LQE 1LQE 1LQE Matter et al., 2002
beta trypsin; complex with a phosphonate inhibitor ZAP 1.80 Å 1MAX 1MAX 1MAX 1MAX 1MAX 1MAX Bertrand et al., 1996
beta trypsin; complex with a phosphonate inhibitor ZAP 1.80 Å 1MAY 1MAY 1MAY 1MAY 1MAY 1MAY Bertrand et al., 1996
beta-trypsin; complex with MCTI-A inhibitor 1.80 Å 1MCU 1MCU 1MCU 1MCU 1MCU 1MCU Zhu et al., 1999
complex with factor Xa-specific inhibitor BX5633 1.90 Å 1MTS 1MTS 1MTS 1MTS 1MTS 1MTS Stubbs et al., 1995
complex with factor Xa-specific inhibitor BX5633 1.90 Å 1MTU 1MTU 1MTU 1MTU 1MTU 1MTU Stubbs et al., 1995
complex with factor Xa-specific inhibitor BX5633 1.90 Å 1MTV 1MTV 1MTV 1MTV 1MTV 1MTV Stubbs et al., 1995
complex with factor Xa-specific inhibitor DX9056A 1.90 Å 1MTW 1MTW 1MTW 1MTW 1MTW 1MTW Stubbs et al., 1995
rip-phasing 1.40 Å 1N6X 1N6X 1N6X 1N6X 1N6X 1N6X Ravelli et al., 2003
rip-phasing on bovine trypsin 1.40 Å 1N6Y 1N6Y 1N6Y 1N6Y 1N6Y 1N6Y Ravelli et al., 2003
potent, small molecule inhibitors of human mast cell tryptase. anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone 1.90 Å 1NC6 1NC6 1NC6 1NC6 1NC6 1NC6 Costanzo et al., 2003
modified beta-trypsin 1.80 Å 1NTP 1NTP 1NTP 1NTP 1NTP 1NTP Kossiakoff, 1984
complex with inhibitor CRA_10433 1.77 Å 1O2H 1O2H 1O2H 1O2H 1O2H 1O2H Katz et al., 2003
complex with inhibitor CRA_10655 1.50 Å 1O2I 1O2I 1O2I 1O2I 1O2I 1O2I Katz et al., 2003
complex with inhibitor 2-5-[amino(iminio)methyl]-1H-benzimidazol-2-yl-6-isobutoxybenzenolate (CRA_10656) 1.65 Å 1O2J 1O2J 1O2J 1O2J 1O2J 1O2J Katz et al., 2003
complex with inhibitor 2-5-[amino(iminio)methyl]-1H-benzimidazol-2-yl-6-isobutoxybenzenolate (CRA_10656) 1.63 Å 1O2K 1O2K 1O2K 1O2K 1O2K 1O2K Katz et al., 2003
complex with inhibitor 3-5-[amino(iminio)methyl]-6-chloro-1H-benzimidazol-2-yl-1,1'-biphenyl-2-olate (CRA_10762) 1.68 Å 1O2L 1O2L 1O2L 1O2L 1O2L 1O2L Katz et al., 2003
complex with inhibitor 3-5-[amino(iminio)methyl]-6-chloro-1H-benzimidazol-2-yl-1,1'-biphenyl-2-olate (CRA_10762) 1.69 Å 1O2M 1O2M 1O2M 1O2M 1O2M 1O2M Katz et al., 2003
complex with inhibitor 3-5-[amino(iminio)methyl]-6-chloro-1H-benzimidazol-2-yl-1,1'-biphenyl-2-olate (CRA_10762) 1.50 Å 1O2N 1O2N 1O2N 1O2N 1O2N 1O2N Katz et al., 2003
complex with inhibitor 2-5-[amino(iminio)methyl]-6-fluoro-1H-benzimidazol-2-yl-6-isobutoxybenzenolate (CRA_10950) 1.63 Å 1O2O 1O2O 1O2O 1O2O 1O2O 1O2O Katz et al., 2003
mature  peptidase 1.47 Å 1O2P 1O2P 1O2P 1O2P 1O2P 1O2P Katz et al., 2003
mature  peptidase 1.50 Å 1O2Q 1O2Q 1O2Q 1O2Q 1O2Q 1O2Q Katz et al., 2003
mature  peptidase 1.45 Å 1O2R 1O2R 1O2R 1O2R 1O2R 1O2R Katz et al., 2003
mature  peptidase 1.65 Å 1O2S 1O2S 1O2S 1O2S 1O2S 1O2S Katz et al., 2003
mature  peptidase 1.62 Å 1O2T 1O2T 1O2T 1O2T 1O2T 1O2T Katz et al., 2003
mature  peptidase 1.41 Å 1O2U 1O2U 1O2U 1O2U 1O2U 1O2U Katz et al., 2003
mature  peptidase 1.50 Å 1O2V 1O2V 1O2V 1O2V 1O2V 1O2V Katz et al., 2003
mature  peptidase 1.38 Å 1O2W 1O2W 1O2W 1O2W 1O2W 1O2W Katz et al., 2003
mature  peptidase 1.46 Å 1O2X 1O2X 1O2X 1O2X 1O2X 1O2X Katz et al., 2003
mature  peptidase 1.45 Å 1O2Y 1O2Y 1O2Y 1O2Y 1O2Y 1O2Y Katz et al., 2003
mature  peptidase 1.65 Å 1O2Z 1O2Z 1O2Z 1O2Z 1O2Z 1O2Z Katz et al., 2003
mature  peptidase 1.55 Å 1O30 1O30 1O30 1O30 1O30 1O30 Katz et al., 2003
mature  peptidase 1.66 Å 1O31 1O31 1O31 1O31 1O31 1O31 Katz et al., 2003
mature  peptidase 1.78 Å 1O32 1O32 1O32 1O32 1O32 1O32 Katz et al., 2003
mature  peptidase 1.46 Å 1O33 1O33 1O33 1O33 1O33 1O33 Katz et al., 2003
mature  peptidase 1.50 Å 1O34 1O34 1O34 1O34 1O34 1O34 Katz et al., 2003
mature  peptidase 1.41 Å 1O35 1O35 1O35 1O35 1O35 1O35 Katz et al., 2003
mature  peptidase 1.70 Å 1O36 1O36 1O36 1O36 1O36 1O36 Katz et al., 2003
mature  peptidase 1.45 Å 1O37 1O37 1O37 1O37 1O37 1O37 Katz et al., 2003
mature  peptidase 1.38 Å 1O38 1O38 1O38 1O38 1O38 1O38 Katz et al., 2003
mature  peptidase 1.59 Å 1O39 1O39 1O39 1O39 1O39 1O39 Katz et al., 2003
mature  peptidase 2.00 Å 1O3A 1O3A 1O3A 1O3A 1O3A 1O3A Katz et al., 2003
mature  peptidase 1.75 Å 1O3B 1O3B 1O3B 1O3B 1O3B 1O3B Katz et al., 2003
mature  peptidase 1.64 Å 1O3C 1O3C 1O3C 1O3C 1O3C 1O3C Katz et al., 2003
mature  peptidase 1.33 Å 1O3D 1O3D 1O3D 1O3D 1O3D 1O3D Katz et al., 2003
mature  peptidase 1.64 Å 1O3E 1O3E 1O3E 1O3E 1O3E 1O3E Katz et al., 2003
mature  peptidase 1.55 Å 1O3F 1O3F 1O3F 1O3F 1O3F 1O3F Katz et al., 2003
mature  peptidase 1.55 Å 1O3G 1O3G 1O3G 1O3G 1O3G 1O3G Katz et al., 2003
mature  peptidase 1.53 Å 1O3H 1O3H 1O3H 1O3H 1O3H 1O3H Katz et al., 2003
mature  peptidase 1.51 Å 1O3I 1O3I 1O3I 1O3I 1O3I 1O3I Katz et al., 2003
mature  peptidase 1.40 Å 1O3J 1O3J 1O3J 1O3J 1O3J 1O3J Katz et al., 2003
mature  peptidase 1.43 Å 1O3K 1O3K 1O3K 1O3K 1O3K 1O3K Katz et al., 2003
mature  peptidase 1.40 Å 1O3L 1O3L 1O3L 1O3L 1O3L 1O3L Katz et al., 2003
mature  peptidase 1.55 Å 1O3M 1O3M 1O3M 1O3M 1O3M 1O3M Katz et al., 2003
mature  peptidase 1.55 Å 1O3N 1O3N 1O3N 1O3N 1O3N 1O3N Katz et al., 2003
mature  peptidase 1.55 Å 1O3O 1O3O 1O3O 1O3O 1O3O 1O3O Katz et al., 2003
non-covalent complex between alpha-1-pi-pittsburgh and s195a trypsin 2.30 Å 1OPH 1OPH 1OPH 1OPH 1OPH 1OPH Dementiev et al., 2003
complex with a synthetic 11 peptide inhibitor 2.00 Å 1OX1 1OX1 1OX1 1OX1 1OX1 1OX1
trypsin inhibitor complex 1.90 Å 1OYQ 1OYQ 1OYQ 1OYQ 1OYQ 1OYQ Nar et al., 2001
structural consequences of accommodation of four non- cognate amino-acid residues in the s1 pocket of bovine trypsin and chymotrypsin 1.65 Å 1P2I 1P2I 1P2I 1P2I 1P2I 1P2I Helland et al., 2003
structural consequences of accommodation of four non- cognate amino-acid residues in the s1 pocket of bovine trypsin and chymotrypsin 1.35 Å 1P2J 1P2J 1P2J 1P2J 1P2J 1P2J Helland et al., 2003
structural consequences of accommodation of four non- cognate amino-acid residues in the s1 pocket of bovine trypsin and chymotrypsin 1.60 Å 1P2K 1P2K 1P2K 1P2K 1P2K 1P2K Helland et al., 2003
complex with NAPAP 1.80 Å 1PPC 1PPC 1PPC 1PPC 1PPC 1PPC Bode et al., 1990
complex with squash trypsin inhibitor 2.00 Å 1PPE 1PPE 1PPE 1PPE 1PPE 1PPE Bode et al., 1989
complex with 3-TAPAP 1.90 Å 1PPH 1PPH 1PPH 1PPH 1PPH 1PPH Turk et al., 1991
complex with 2-aminobenzimidazole 1.80 Å 1QA0 1QA0 1QA0 1QA0 1QA0 1QA0 Whitlow et al., 1999
complex with ZK-806974 inhibitor 1.80 Å 1QB1 1QB1 1QB1 1QB1 1QB1 1QB1 Whitlow et al., 1999
complex with ZK-805623 inhibitor 1.80 Å 1QB6 1QB6 1QB6 1QB6 1QB6 1QB6 Whitlow et al., 1999
complex with ZK-806450 inhibitor 1.80 Å 1QB9 1QB9 1QB9 1QB9 1QB9 1QB9 Whitlow et al., 1999
complex with ZK-806688 inhibitor 1.80 Å 1QBN 1QBN 1QBN 1QBN 1QBN 1QBN Whitlow et al., 1999
complex with ZK-806711 inhibitor 1.80 Å 1QBO 1QBO 1QBO 1QBO 1QBO 1QBO Whitlow et al., 1999
complex with RWJ-51084 inhibitor 1.80 Å 1QCP 1QCP 1QCP 1QCP 1QCP 1QCP Recacha et al., 1999
complex with [4-(6-chloro-naphthalene-2-sulfonyl)-piperazin-1-yl]-(3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-yl)-methanone 2.10 Å 1QL7 1QL7 1QL7 1QL7 1QL7 1QL7 Stubbs et al., 2002
complex with [4-(6-chloro-naphthalene-2-sulfonyl)-piperazin-1-yl]-(3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-yl)-methanone 3.00 Å 1QL8 1QL8 1QL8 1QL8 1QL8 1QL8 Stubbs et al., 2002
complex with 1-(4-tert-butylcarbamoyl-piperazine-1-carbonyl)-3-(3-guanidino- propyl)-4-oxo-azetidine-2-carboxylic acid 1.70 Å 1RXP 1RXP 1RXP 1RXP 1RXP 1RXP Sutton et al., 2004
mature  peptidase 1.02 Å 1S0Q 1S0Q 1S0Q 1S0Q 1S0Q 1S0Q
complex with benzamidine 1.02 Å 1S0R 1S0R 1S0R 1S0R 1S0R 1S0R
beta-trypsin; complex with mung bean inhibitor lysine active fragment 1.80 Å 1SBW 1SBW 1SBW 1SBW 1SBW 1SBW Zhu et al., 1999
complex with sunflower seed serpin inhibitor 1.65 Å 1SFI 1SFI 1SFI 1SFI 1SFI 1SFI Luckett et al., 1999
complex with Bowman-Birk inhibitor 2.10 Å 1SMF 1SMF 1SMF 1SMF 1SMF 1SMF Li et al., 1994
complex with adzuki bean Bowman-Birk inhibitor 2.30 Å 1TAB 1TAB 1TAB 1TAB 1TAB 1TAB Tsunogae et al., 1986
complex with inhibitor domain from Alzheimer's amyloid beta protein precursor 1.80 Å 1TAW 1TAW 1TAW 1TAW 1TAW 1TAW Scheidig et al., 1997
precursor 1.80 Å 1TGB 1TGB 1TGB 1TGB 1TGB 1TGB Fehlhammer et al., 1977
precursor, in 50% methanol 1.80 Å 1TGC 1TGC 1TGC 1TGC 1TGC 1TGC
precursor 1.65 Å 1TGN 1TGN 1TGN 1TGN 1TGN 1TGN Kossiakoff et al., 1977
complex with pig secretory trypsin inhibitor 1.80 Å 1TGS 1TGS 1TGS 1TGS 1TGS 1TGS Bolognesi et al., 1982
precursor at 173 degrees 1.70 Å 1TGT 1TGT 1TGT 1TGT 1TGT 1TGT
beta-trypsin; high-packing density form in cyclohexane 1.93 Å 1TIO 1TIO 1TIO 1TIO 1TIO 1TIO Zhu et al., 1998
beta-trypsin, orthorhombic at pH 5.3 1.50 Å 1TLD 1TLD 1TLD 1TLD 1TLD 1TLD Bartunik et al., 1989
complex with aminomethylcyclohexane 1.80 Å 1TNG 1TNG 1TNG 1TNG 1TNG 1TNG Kurinov & Harrison, 1994
complex with 4-fluorobenzylamine 1.80 Å 1TNH 1TNH 1TNH 1TNH 1TNH 1TNH Kurinov & Harrison, 1994
complex with 4-phenylbutylamine 1.90 Å 1TNI 1TNI 1TNI 1TNI 1TNI 1TNI Kurinov & Harrison, 1994
complex with 2-phenylethylamine 1.80 Å 1TNJ 1TNJ 1TNJ 1TNJ 1TNJ 1TNJ Kurinov & Harrison, 1994
complex with 3-phenylpropylamine 1.80 Å 1TNK 1TNK 1TNK 1TNK 1TNK 1TNK Kurinov & Harrison, 1994
complex with tranylcypromine 1.90 Å 1TNL 1TNL 1TNL 1TNL 1TNL 1TNL Kurinov & Harrison, 1994
anhydro-trypsin; complex with pancreatic trypsin inhibitor 1.90 Å 1TPA 1TPA 1TPA 1TPA 1TPA 1TPA Marquart et al., 1983
beta-trypsin at pH 5.0 1.70 Å 1TPO 1TPO 1TPO 1TPO 1TPO 1TPO
beta-trypsin; complex with p-amidino-phenyl pyruvate 1.40 Å 1TPP 1TPP 1TPP 1TPP 1TPP 1TPP Marquart et al., 1983
complex with inhibitor A90720A 1.90 Å 1TPS 1TPS 1TPS 1TPS 1TPS 1TPS Lee et al., 1994
bovine trypsin complexed with p- amidinophenylmethylphosphinic acid (ampa) 1.75 Å 1TX7 1TX7 1TX7 1TX7 1TX7 1TX7 Cui et al., 2002
bovine trypsin complexed with amso 1.70 Å 1TX8 1TX8 1TX8 1TX8 1TX8 1TX8 Rumthao et al., 2004
complex with cyclotheonamide A 2.00 Å 1TYN 1TYN 1TYN 1TYN 1TYN 1TYN
trypsin specificity as elucidated by lie calculations, x- ray structures and association constant measurements 1.15 Å 1UTN 1UTN 1UTN 1UTN 1UTN 1UTN Leiros et al., 2004
trypsin specificity as elucidated by lie calculations, x- ray structures and association constant measurements 1.15 Å 1UTO 1UTO 1UTO 1UTO 1UTO 1UTO Leiros et al., 2004
trypsin specificity as elucidated by lie calculations, x- ray structures and association constant measurements 1.30 Å 1UTP 1UTP 1UTP 1UTP 1UTP 1UTP Leiros et al., 2004
trypsin specificity as elucidated by lie calculations, x- ray structures and association constant measurements 1.15 Å 1UTQ 1UTQ 1UTQ 1UTQ 1UTQ 1UTQ Leiros et al., 2004
benzamidine in complex with bovine trypsin variant x(ssri) bt.c1 1.90 Å 1V2J 1V2J 1V2J 1V2J 1V2J 1V2J Rauh et al., 2004
variant X(triple.Glu)BT.D2; complex with factor Xa specific inhibitor 2.00 Å 1V2K 1V2K 1V2K 1V2K 1V2K 1V2K Rauh et al., 2004
variant X(triple.Glu)BT.D2; complex with benzamidine 1.60 Å 1V2L 1V2L 1V2L 1V2L 1V2L 1V2L Rauh et al., 2004
variant X(triple.Glu)BT.A1; complex with benzamidine 1.65 Å 1V2M 1V2M 1V2M 1V2M 1V2M 1V2M Rauh et al., 2004
potent factor xa inhibitor in complex with bovine trypsin variant x(99/175/190)bt 1.80 Å 1V2N 1V2N 1V2N 1V2N 1V2N 1V2N Rauh et al., 2004
trypsin inhibitor in complex with bovine trypsin variant x(ssyi)bt.b4 1.62 Å 1V2O 1V2O 1V2O 1V2O 1V2O 1V2O Rauh et al., 2004
trypsin inhibitor in complex with bovine trypsin variant x(ssyi)bt.a4 1.92 Å 1V2P 1V2P 1V2P 1V2P 1V2P 1V2P Rauh et al., 2004
trypsin inhibitor in complex with bovine trypsin variant x(sswi)bt.b4 2.30 Å 1V2Q 1V2Q 1V2Q 1V2Q 1V2Q 1V2Q Rauh et al., 2004
trypsin inhibitor in complex with bovine trypsin variant x(ssri)bt.b4 1.70 Å 1V2R 1V2R 1V2R 1V2R 1V2R 1V2R Rauh et al., 2004
benzamidine in complex with bovine trypsin variant x(ssfi.glu)bt.d1 1.72 Å 1V2S 1V2S 1V2S 1V2S 1V2S 1V2S Rauh et al., 2004
trypsin inhibitor in complex with bovine trypsin variant x(ssfi.glu)bt.b4 1.90 Å 1V2T 1V2T 1V2T 1V2T 1V2T 1V2T Rauh et al., 2004
benzamidine in complex with bovine trypsin varinat x(ssai) bt.d1 1.80 Å 1V2U 1V2U 1V2U 1V2U 1V2U 1V2U Rauh et al., 2004
benzamidine in complex with bovine trypsin variant x(ssai) bt.c1 1.80 Å 1V2V 1V2V 1V2V 1V2V 1V2V 1V2V Rauh et al., 2004
trypsin inhibitor in complex with bovine trypsin variant x(ssai)bt.b4 1.75 Å 1V2W 1V2W 1V2W 1V2W 1V2W 1V2W Rauh et al., 2004
complex with bis(5-amidino-benzimidazolyl) methane zinc 2.04 Å 1XUF 1XUF 1XUF 1XUF 1XUF 1XUF Katz et al., 1998
complex with bis(5-amidino-benzimidazolyl) methane 1.50 Å 1XUG 1XUG 1XUG 1XUG 1XUG 1XUG Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methanone and cobalt, pH 8.2 2.37 Å 1XUH 1XUH 1XUH 1XUH 1XUH 1XUH Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methanone, pH 8.2 1.50 Å 1XUI 1XUI 1XUI 1XUI 1XUI 1XUI Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methanone zinc, pH 8.2 1.92 Å 1XUJ 1XUJ 1XUJ 1XUJ 1XUJ 1XUJ Katz et al., 1998
complex with bis(5-amidino-2-benzimidazolyl)methanone, pH 5.9 2.04 Å 1XUK 1XUK 1XUK 1XUK 1XUK 1XUK Katz et al., 1998
trypsin inhibitor complex 1.80 Å 1Y3U 1Y3U 1Y3U 1Y3U 1Y3U 1Y3U
trypsin inhibitor complex 1.60 Å 1Y3V 1Y3V 1Y3V 1Y3V 1Y3V 1Y3V Fokkens & Klebe, 2006
trypsin inhibitor complex 1.80 Å 1Y3W 1Y3W 1Y3W 1Y3W 1Y3W 1Y3W Fokkens & Klebe, 2006
trypsin inhibitor complex 1.70 Å 1Y3X 1Y3X 1Y3X 1Y3X 1Y3X 1Y3X Fokkens & Klebe, 2006
trypsin inhibitor complex 1.75 Å 1Y3Y 1Y3Y 1Y3Y 1Y3Y 1Y3Y 1Y3Y Fokkens & Klebe, 2006
dianhydrosugar-based benzamidine, factor xa specific inhibitor in complex with bovine trypsin mutant 1.20 Å 1Y59 1Y59 1Y59 1Y59 1Y59 1Y59 Di et al., 2007
dianhydrosugar-based benzamidine, factor xa specific inhibitor in complex with bovine trypsin mutant 1.40 Å 1Y5A 1Y5A 1Y5A 1Y5A 1Y5A 1Y5A Di et al., 2007
dianhydrosugar-based benzamidine, factor xa specific inhibitor in complex with bovine trypsin mutant 1.65 Å 1Y5B 1Y5B 1Y5B 1Y5B 1Y5B 1Y5B Di et al., 2007
dianhydrosugar-based benzamidine, factor xa specific inhibitor in complex with bovine trypsin mutant 1.60 Å 1Y5U 1Y5U 1Y5U 1Y5U 1Y5U 1Y5U Di et al., 2007
trypsin inhibitor complex 2.10 Å 1YP9 1YP9 1YP9 1YP9 1YP9 1YP9 Fokkens & Klebe, 2006
complex with 4-sulfonylbenzene-norVal-3-piperidyl-N-guanidino-L-Ala inhibitor 2.10 Å 1YYY 1YYY 1YYY 1YYY 1YYY 1YYY Krishnan et al., 1998
complex with Kunitz domain 1 of tissue factor pathway inhibitor-2 1.80 Å 1ZR0 1ZR0 1ZR0 1ZR0 1ZR0 1ZR0 Schmidt et al., 2005
complex with SO2-norVal-Gly-3-piperidyl-N-guanidino-L-Ala 1.90 Å 1ZZZ 1ZZZ 1ZZZ 1ZZZ 1ZZZ 1ZZZ Krishnan et al., 1998
mature  peptidase 2.10 Å 2A7H 2A7H 2A7H 2A7H 2A7H 2A7H Mueller-Dieckmann et al., 2005
succinyl-aapr-trypsin acyl-enzyme at 1.15 a resolution 1.15 Å 2AGE 2AGE 2AGE 2AGE 2AGE 2AGE Radisky et al., 2006
succinyl-aapk-trypsin acyl-enzyme at 1.28 a resolution 1.28 Å 2AGG 2AGG 2AGG 2AGG 2AGG 2AGG Radisky et al., 2006
complex with leupeptin 1.14 Å 2AGI 2AGI 2AGI 2AGI 2AGI 2AGI Radisky et al., 2006
guanidinobenzoyl-trypsin acyl-enzyme at 1.13 a resolution 1.13 Å 2AH4 2AH4 2AH4 2AH4 2AH4 2AH4 Radisky et al., 2006
complex with 2-3'-[5'-methoxy-2'-(N-p-diaminomethylphenyl)amido]-1'-pyrido-5-(N-2''-t-butylethanol)amidobenzoic acid and benzamidine 0.97 Å 2AYW 2AYW 2AYW 2AYW 2AYW 2AYW Sherawat et al., 2007
trypsin before a high dose x-ray "burn" 1.20 Å 2BLV 2BLV 2BLV 2BLV 2BLV 2BLV Nanao et al., 2005
trypsin after a high dose x-ray "burn" 1.20 Å 2BLW 2BLW 2BLW 2BLW 2BLW 2BLW Nanao et al., 2005
complex with squash seed inhibitor 1.50 Å 2BTC 2BTC 2BTC 2BTC 2BTC 2BTC Helland et al., 1999
mature  peptidase 1.30 Å 2BY5 2BY5 2BY5 2BY5 2BY5 2BY5 Leiros et al., 2006
mature  peptidase 1.30 Å 2BY6 2BY6 2BY6 2BY6 2BY6 2BY6 Leiros et al., 2006
mature  peptidase 1.30 Å 2BY7 2BY7 2BY7 2BY7 2BY7 2BY7 Leiros et al., 2006
mature  peptidase 1.30 Å 2BY8 2BY8 2BY8 2BY8 2BY8 2BY8 Leiros et al., 2006
mature  peptidase 1.30 Å 2BY9 2BY9 2BY9 2BY9 2BY9 2BY9 Leiros et al., 2006
mature  peptidase 1.30 Å 2BYA 2BYA 2BYA 2BYA 2BYA 2BYA Leiros et al., 2006
complex with benzylamine 1.90 Å 2BZA 2BZA 2BZA 2BZA 2BZA 2BZA Ota et al., 1999
complex with Veronica trypsin inhibitor 2.25 Å 2CMY 2CMY 2CMY 2CMY 2CMY 2CMY Conners et al., 2007
structure of hyper-vil-trypsin 2.00 Å 2D8W 2D8W 2D8W 2D8W 2D8W 2D8W Miyatake et al., 2006
complex with infestin 1 2.50 Å 2F3C 2F3C 2F3C 2F3C 2F3C 2F3C Campos et al., 2012
complex with BPTI variant (Cys14Ser, Cys38Ser) 1.58 Å 2FI3 2FI3 2FI3 2FI3 2FI3 2FI3 Zakharova et al., 2008
complex with BPTI variant (Cys14Ser) 1.58 Å 2FI4 2FI4 2FI4 2FI4 2FI4 2FI4 Zakharova et al., 2008
complex with BPTI variant (Cys38Ser) 1.58 Å 2FI5 2FI5 2FI5 2FI5 2FI5 2FI5 Zakharova et al., 2008
complex with BPTI at 100K 1.62 Å 2FTL 2FTL 2FTL 2FTL 2FTL 2FTL Hanson et al., 2007
complex with the BPTI variant (Tyr35Gly) 1.65 Å 2FTM 2FTM 2FTM 2FTM 2FTM 2FTM Hanson et al., 2007
bovine trypsin bound by 4-piperidinebutyrate to make acylenzyme complex 1.65 Å 2FX4 2FX4 2FX4 2FX4 2FX4 2FX4 McGrath et al., 2006
bovine trypsin complexed with 2-aminobenzamidazole 1.57 Å 2FX6 2FX6 2FX6 2FX6 2FX6 2FX6 McGrath et al., 2006
anomalous substructure of trypsin (p3121) 1.82 Å 2G55 2G55 2G55 2G55 2G55 2G55 Mueller-Dieckmann et al., 2007
complex with indole-amidine 1.51 Å 2G5N 2G5N 2G5N 2G5N 2G5N 2G5N
indole-amidine complexes with bovine trypsin 1.45 Å 2G5V 2G5V 2G5V 2G5V 2G5V 2G5V
complex with Bowman-Birk inhibitor from Vigna unguiculata seeds 1.55 Å 2G81 2G81 2G81 2G81 2G81 2G81 Barbosa et al., 2007
indole-amidine complexes with bovine trypsin 1.41 Å 2G8T 2G8T 2G8T 2G8T 2G8T 2G8T
complex with Bowman-Birk inhibitor from snail medic 2.00 Å 2ILN 2ILN 2ILN 2ILN 2ILN 2ILN Capaldi et al., 2007
complex with benzamidine containing polypeptide mediated crystal contacts 1.50 Å 2J9N 2J9N 2J9N 2J9N 2J9N 2J9N Viola et al., 2007
the crystal structure of bovine trypsin complexed with a small inhibition peptide orb2k 1.70 Å 2O9Q 2O9Q 2O9Q 2O9Q 2O9Q 2O9Q
complex with nicotinamide 1.56 Å 2OTV 2OTV 2OTV 2OTV 2OTV 2OTV
complex with benzamidine at high temperature (35 c) 1.32 Å 2OXS 2OXS 2OXS 2OXS 2OXS 2OXS
complex with synthetic peptide derived from Veronica trypsin inhibitor 1.56 Å 2PLX 2PLX 2PLX 2PLX 2PLX 2PLX Conners et al., 2007
complex with pancreatic trypsin inhibitor 1.90 Å 2PTC 2PTC 2PTC 2PTC 2PTC 2PTC
orthorhombic 1.55 Å 2PTN 2PTN 2PTN 2PTN 2PTN 2PTN
complex with Bowman-Birk inhibitor from rice bran 3.00 Å 2QN5 2QN5 2QN5 2QN5 2QN5 2QN5 Lin et al., 2006
complex with engineered trypsin inhibitor 2.60 Å 2QYI 2QYI 2QYI 2QYI 2QYI 2QYI Khamrui et al., 2005
precursor 1.80 Å 2TGA 2TGA 2TGA 2TGA 2TGA 2TGA
precursor; complex with diisopropylphosphoryl 2.10 Å 2TGD 2TGD 2TGD 2TGD 2TGD 2TGD
precursor; complex with pancreatic trypsin inhibitor 1.90 Å 2TGP 2TGP 2TGP 2TGP 2TGP 2TGP
precursor at 103 degrees 1.70 Å 2TGT 2TGT 2TGT 2TGT 2TGT 2TGT
low packing density form in cyclohexane 1.93 Å 2TIO 2TIO 2TIO 2TIO 2TIO 2TIO Zhu et al., 1998
complex with modified Streptomyces subtilisin inhibitor 2.60 Å 2TLD 2TLD 2TLD 2TLD 2TLD 2TLD Takeuchi et al., 1992
precursor; complex with pancreatic trypsin inhibitor 2.10 Å 2TPI 2TPI 2TPI 2TPI 2TPI 2TPI
structure of a tick tryptase inhibitor in complex with bovine trypsin 1.15 Å 2UUY 2UUY 2UUY 2UUY 2UUY 2UUY Paesen et al., 2007
mature  peptidase 0.93 Å 2XTT 2XTT 2XTT 2XTT 2XTT 2XTT Wahlgren et al., 2011
exploring trypsin s3 pocket 1.67 Å 2ZDK 2ZDK 2ZDK 2ZDK 2ZDK 2ZDK Brandt et al., 2011
exploring trypsin s3 pocket 1.80 Å 2ZDL 2ZDL 2ZDL 2ZDL 2ZDL 2ZDL Brandt et al., 2011
exploring trypsin s3 pocket 1.93 Å 2ZDM 2ZDM 2ZDM 2ZDM 2ZDM 2ZDM Brandt et al., 2011
exploring trypsin s3 pocket 1.98 Å 2ZDN 2ZDN 2ZDN 2ZDN 2ZDN 2ZDN Brandt et al., 2011
exploring trypsin s3 pocket 1.51 Å 2ZFS 2ZFS 2ZFS 2ZFS 2ZFS 2ZFS Brandt et al., 2011
exploring trypsin s3 pocket 1.76 Å 2ZFT 2ZFT 2ZFT 2ZFT 2ZFT 2ZFT Brandt et al., 2011
exploring trypsin s3 pocket 1.94 Å 2ZHD 2ZHD 2ZHD 2ZHD 2ZHD 2ZHD Brandt et al., 2011
mature  peptidase 1.68 Å 2ZQ1 2ZQ1 2ZQ1 2ZQ1 2ZQ1 2ZQ1 Brandt et al., 2011
mature  peptidase 1.40 Å 2ZQ2 2ZQ2 2ZQ2 2ZQ2 2ZQ2 2ZQ2 Brandt et al., 2011
mature  peptidase 1.75 Å 3A7T 3A7T 3A7T 3A7T 3A7T 3A7T
mature  peptidase 1.75 Å 3A7V 3A7V 3A7V 3A7V 3A7V 3A7V
mature  peptidase 1.75 Å 3A7W 3A7W 3A7W 3A7W 3A7W 3A7W
mature  peptidase 1.75 Å 3A7X 3A7X 3A7X 3A7X 3A7X 3A7X
mature  peptidase 1.81 Å 3A7Y 3A7Y 3A7Y 3A7Y 3A7Y 3A7Y
mature  peptidase 1.80 Å 3A7Z 3A7Z 3A7Z 3A7Z 3A7Z 3A7Z
mature  peptidase 1.75 Å 3A80 3A80 3A80 3A80 3A80 3A80
mature  peptidase 1.78 Å 3A81 3A81 3A81 3A81 3A81 3A81
mature  peptidase 1.75 Å 3A82 3A82 3A82 3A82 3A82 3A82
mature  peptidase 1.78 Å 3A83 3A83 3A83 3A83 3A83 3A83
mature  peptidase 1.75 Å 3A84 3A84 3A84 3A84 3A84 3A84
mature  peptidase 1.75 Å 3A85 3A85 3A85 3A85 3A85 3A85
mature  peptidase 1.75 Å 3A86 3A86 3A86 3A86 3A86 3A86
mature  peptidase 1.75 Å 3A87 3A87 3A87 3A87 3A87 3A87
mature  peptidase 1.75 Å 3A88 3A88 3A88 3A88 3A88 3A88
mature  peptidase 1.80 Å 3A89 3A89 3A89 3A89 3A89 3A89
mature  peptidase 1.40 Å 3A8A 3A8A 3A8A 3A8A 3A8A 3A8A
mature  peptidase 1.75 Å 3A8B 3A8B 3A8B 3A8B 3A8B 3A8B
mature  peptidase 1.85 Å 3A8C 3A8C 3A8C 3A8C 3A8C 3A8C
mature  peptidase 1.75 Å 3A8D 3A8D 3A8D 3A8D 3A8D 3A8D
mature  peptidase 1.75 Å 3AAS 3AAS 3AAS 3AAS 3AAS 3AAS Iyaguchi et al., 2010
mature  peptidase 1.80 Å 3AAU 3AAU 3AAU 3AAU 3AAU 3AAU Iyaguchi et al., 2010
mature  peptidase 1.70 Å 3AAV 3AAV 3AAV 3AAV 3AAV 3AAV Iyaguchi et al., 2010
mature  peptidase 1.71 Å 3ATI 3ATI 3ATI 3ATI 3ATI 3ATI
mature  peptidase 1.74 Å 3ATK 3ATK 3ATK 3ATK 3ATK 3ATK
mature  peptidase 1.74 Å 3ATL 3ATL 3ATL 3ATL 3ATL 3ATL
mature  peptidase 1.72 Å 3ATM 3ATM 3ATM 3ATM 3ATM 3ATM
complex with bovine pancreatic trypsin inhibitor Lys15Asp and Met52Leu mutant 1.90 Å 3BTD 3BTD 3BTD 3BTD 3BTD 3BTD Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor Lys50Glu and Met87Leu mutant 1.85 Å 3BTE 3BTE 3BTE 3BTE 3BTE 3BTE Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor Lys15Phe and Met52Leu mutant 1.80 Å 3BTF 3BTF 3BTF 3BTF 3BTF 3BTF Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor Lys15Gly and Met52Leu mutant 1.90 Å 3BTG 3BTG 3BTG 3BTG 3BTG 3BTG Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor Lys51His and Met52Leu mutant 1.75 Å 3BTH 3BTH 3BTH 3BTH 3BTH 3BTH Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor 1.85 Å 3BTK 3BTK 3BTK 3BTK 3BTK 3BTK Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor Lys15Met and Met52Leu mutant 1.80 Å 3BTM 3BTM 3BTM 3BTM 3BTM 3BTM Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor Lys15Gln and Met52Leu mutant 1.90 Å 3BTQ 3BTQ 3BTQ 3BTQ 3BTQ 3BTQ Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor Lys15Thr and Met52Leu mutant 1.90 Å 3BTT 3BTT 3BTT 3BTT 3BTT 3BTT Helland et al., 1999
complex with bovine pancreatic trypsin inhibitor Lys15Trp and Met52Leu mutant 2.05 Å 3BTW 3BTW 3BTW 3BTW 3BTW 3BTW Helland et al., 1999
complex with textilinin-1 1.64 Å 3D65 3D65 3D65 3D65 3D65 3D65
mature  peptidase 2.48 Å 3E8L 3E8L 3E8L 3E8L 3E8L 3E8L Bao et al., 2009
mature  peptidase 1.57 Å 3GY2 3GY2 3GY2 3GY2 3GY2 3GY2 Perilo et al., 2010
mature  peptidase 1.70 Å 3GY3 3GY3 3GY3 3GY3 3GY3 3GY3 Perilo et al., 2010
mature  peptidase 1.55 Å 3GY4 3GY4 3GY4 3GY4 3GY4 3GY4 Perilo et al., 2010
mature  peptidase 1.57 Å 3GY5 3GY5 3GY5 3GY5 3GY5 3GY5 Perilo et al., 2010
mature  peptidase 1.70 Å 3GY6 3GY6 3GY6 3GY6 3GY6 3GY6 Perilo et al., 2010
mature  peptidase 1.55 Å 3GY7 3GY7 3GY7 3GY7 3GY7 3GY7 Perilo et al., 2010
mature  peptidase 1.75 Å 3GY8 3GY8 3GY8 3GY8 3GY8 3GY8 Perilo et al., 2010
mature  peptidase 2.40 Å 3I29 3I29 3I29 3I29 3I29 3I29 Majumder et al., 2012
mature  peptidase 1.55 Å 3ITI 3ITI 3ITI 3ITI 3ITI 3ITI Beck et al., 2009
mature  peptidase 1.55 Å 3LJJ 3LJJ 3LJJ 3LJJ 3LJJ 3LJJ Brandt et al., 2011
mature  peptidase 1.50 Å 3LJO 3LJO 3LJO 3LJO 3LJO 3LJO Brandt et al., 2011
mature  peptidase 2.20 Å 3M35 3M35 3M35 3M35 3M35 3M35 Pruitt et al., 2003
mature  peptidase 1.70 Å 3M7Q 3M7Q 3M7Q 3M7Q 3M7Q 3M7Q Garcia-Fernandez et al., 2012
mature  peptidase 0.80 Å 3MFJ 3MFJ 3MFJ 3MFJ 3MFJ 3MFJ
mature  peptidase 0.80 Å 3MI4 3MI4 3MI4 3MI4 3MI4 3MI4
mature  peptidase 1.15 Å 3NK8 3NK8 3NK8 3NK8 3NK8 3NK8 Vulpetti et al., 2010
mature  peptidase 1.12 Å 3NKK 3NKK 3NKK 3NKK 3NKK 3NKK Vulpetti et al., 2010
mature  peptidase 2.15 Å 3OTJ 3OTJ 3OTJ 3OTJ 3OTJ 3OTJ Kawamura et al., 2011
mature  peptidase 1.18 Å 3PLB 3PLB 3PLB 3PLB 3PLB 3PLB Tziridis et al., 2014
mature  peptidase 1.53 Å 3PLK 3PLK 3PLK 3PLK 3PLK 3PLK Tziridis et al., 2014
mature  peptidase 1.63 Å 3PLP 3PLP 3PLP 3PLP 3PLP 3PLP Tziridis et al., 2014
mature  peptidase 1.53 Å 3PM3 3PM3 3PM3 3PM3 3PM3 3PM3 Tziridis et al., 2014
mature  peptidase 1.45 Å 3PMJ 3PMJ 3PMJ 3PMJ 3PMJ 3PMJ Tziridis et al., 2014
beta-trypsin; complex with benzamidine 1.70 Å 3PTB 3PTB 3PTB 3PTB 3PTB 3PTB
trigonal 1.70 Å 3PTN 3PTN 3PTN 3PTN 3PTN 3PTN
mature  peptidase 1.63 Å 3PWB 3PWB 3PWB 3PWB 3PWB 3PWB Tziridis et al., 2014
mature  peptidase 1.60 Å 3PWC 3PWC 3PWC 3PWC 3PWC 3PWC Tziridis et al., 2014
mature  peptidase 2.00 Å 3PYH 3PYH 3PYH 3PYH 3PYH 3PYH Tziridis et al., 2014
mature  peptidase 1.70 Å 3Q00 3Q00 3Q00 3Q00 3Q00 3Q00 Tziridis et al., 2014
mature  peptidase 2.08 Å 3QK1 3QK1 3QK1 3QK1 3QK1 3QK1 Schopfel et al., 2011
mature  peptidase 2.26 Å 3RDZ 3RDZ 3RDZ 3RDZ 3RDZ 3RDZ Wang et al., 2011
mature  peptidase 1.68 Å 3RU4 3RU4 3RU4 3RU4 3RU4 3RU4
mature  peptidase 1.70 Å 3RXA 3RXA 3RXA 3RXA 3RXA 3RXA
mature  peptidase 1.70 Å 3RXB 3RXB 3RXB 3RXB 3RXB 3RXB
mature  peptidase 1.70 Å 3RXC 3RXC 3RXC 3RXC 3RXC 3RXC
mature  peptidase 1.70 Å 3RXD 3RXD 3RXD 3RXD 3RXD 3RXD
mature  peptidase 1.70 Å 3RXE 3RXE 3RXE 3RXE 3RXE 3RXE
mature  peptidase 1.70 Å 3RXF 3RXF 3RXF 3RXF 3RXF 3RXF
mature  peptidase 1.70 Å 3RXG 3RXG 3RXG 3RXG 3RXG 3RXG
mature  peptidase 1.70 Å 3RXH 3RXH 3RXH 3RXH 3RXH 3RXH
mature  peptidase 1.60 Å 3RXI 3RXI 3RXI 3RXI 3RXI 3RXI
mature  peptidase 1.70 Å 3RXJ 3RXJ 3RXJ 3RXJ 3RXJ 3RXJ
mature  peptidase 1.60 Å 3RXK 3RXK 3RXK 3RXK 3RXK 3RXK
mature  peptidase 1.70 Å 3RXL 3RXL 3RXL 3RXL 3RXL 3RXL
mature  peptidase 1.70 Å 3RXM 3RXM 3RXM 3RXM 3RXM 3RXM
mature  peptidase 1.60 Å 3RXO 3RXO 3RXO 3RXO 3RXO 3RXO
mature  peptidase 1.60 Å 3RXP 3RXP 3RXP 3RXP 3RXP 3RXP
mature  peptidase 1.68 Å 3RXQ 3RXQ 3RXQ 3RXQ 3RXQ 3RXQ
mature  peptidase 1.72 Å 3RXR 3RXR 3RXR 3RXR 3RXR 3RXR
mature  peptidase 1.74 Å 3RXS 3RXS 3RXS 3RXS 3RXS 3RXS
mature  peptidase 1.70 Å 3RXT 3RXT 3RXT 3RXT 3RXT 3RXT
mature  peptidase 1.68 Å 3RXU 3RXU 3RXU 3RXU 3RXU 3RXU
mature  peptidase 1.70 Å 3RXV 3RXV 3RXV 3RXV 3RXV 3RXV
mature  peptidase 1.70 Å 3T25 3T25 3T25 3T25 3T25 3T25 Marshall et al., 2012
mature  peptidase 1.70 Å 3T26 3T26 3T26 3T26 3T26 3T26 Marshall et al., 2012
mature  peptidase 1.95 Å 3T27 3T27 3T27 3T27 3T27 3T27 Marshall et al., 2012
mature  peptidase 2.80 Å 3T28 3T28 3T28 3T28 3T28 3T28 Marshall et al., 2012
mature  peptidase 1.75 Å 3T29 3T29 3T29 3T29 3T29 3T29 Marshall et al., 2012
mature  peptidase 1.90 Å 3TPI 3TPI 3TPI 3TPI 3TPI 3TPI
precursor; complex with pancreatic trypsin inhibitor 1.90 Å 3TPI 3TPI 3TPI 3TPI 3TPI 3TPI
mature  peptidase 1.62 Å 3UNQ 3UNQ 3UNQ 3UNQ 3UNQ 3UNQ Tziridis et al., 2014
mature  peptidase 1.20 Å 3UNR 3UNR 3UNR 3UNR 3UNR 3UNR Fisher et al., 2012
mature  peptidase 1.80 Å 3UNS 3UNS 3UNS 3UNS 3UNS 3UNS Tziridis et al., 2014
mature  peptidase 1.69 Å 3UOP 3UOP 3UOP 3UOP 3UOP 3UOP Tziridis et al., 2014
mature  peptidase 1.54 Å 3UPE 3UPE 3UPE 3UPE 3UPE 3UPE Tziridis et al., 2014
mature  peptidase 1.80 Å 3UQO 3UQO 3UQO 3UQO 3UQO 3UQO Tziridis et al., 2014
mature  peptidase 2.40 Å 3UQV 3UQV 3UQV 3UQV 3UQV 3UQV Tziridis et al., 2014
mature  peptidase 2.10 Å 3UUZ 3UUZ 3UUZ 3UUZ 3UUZ 3UUZ Tziridis et al., 2014
mature  peptidase 1.43 Å 3UWI 3UWI 3UWI 3UWI 3UWI 3UWI Tziridis et al., 2014
mature  peptidase 3.22 Å 3UY9 3UY9 3UY9 3UY9 3UY9 3UY9 Tziridis et al., 2014
mature  peptidase 1.90 Å 3V0X 3V0X 3V0X 3V0X 3V0X 3V0X
mature  peptidase 1.80 Å 3V12 3V12 3V12 3V12 3V12 3V12 Tziridis et al., 2014
mature  peptidase 1.63 Å 3V13 3V13 3V13 3V13 3V13 3V13 Tziridis et al., 2014
mature  peptidase 2.25 Å 3VEQ 3VEQ 3VEQ 3VEQ 3VEQ 3VEQ Majumder et al., 2012
mature  peptidase 1.94 Å 3VPK 3VPK 3VPK 3VPK 3VPK 3VPK Masuda et al., 2013
mature  peptidase 1.60 Å 4AB8 4AB8 4AB8 4AB8 4AB8 4AB8 Newman et al., 2012
mature  peptidase 1.20 Å 4AB9 4AB9 4AB9 4AB9 4AB9 4AB9 Newman et al., 2012
mature  peptidase 1.25 Å 4ABA 4ABA 4ABA 4ABA 4ABA 4ABA Newman et al., 2012
mature  peptidase 1.25 Å 4ABB 4ABB 4ABB 4ABB 4ABB 4ABB Newman et al., 2012
mature  peptidase 1.25 Å 4ABD 4ABD 4ABD 4ABD 4ABD 4ABD Newman et al., 2012
mature  peptidase 1.30 Å 4ABE 4ABE 4ABE 4ABE 4ABE 4ABE Newman et al., 2012
mature  peptidase 1.30 Å 4ABF 4ABF 4ABF 4ABF 4ABF 4ABF Newman et al., 2012
mature  peptidase 1.52 Å 4ABG 4ABG 4ABG 4ABG 4ABG 4ABG Newman et al., 2012
mature  peptidase 1.25 Å 4ABH 4ABH 4ABH 4ABH 4ABH 4ABH Newman et al., 2012
mature  peptidase 1.55 Å 4ABI 4ABI 4ABI 4ABI 4ABI 4ABI Tischler et al., 2012
mature  peptidase 1.45 Å 4ABJ 4ABJ 4ABJ 4ABJ 4ABJ 4ABJ Tischler et al., 2012
complex with spinach trypsin inhibitor III (Phe14Ala mutant) 2.00 Å 4AOQ 4AOQ 4AOQ 4AOQ 4AOQ 4AOQ Glotzbach et al., 2013
complex with cationic trypsin 1.70 Å 4AOR 4AOR 4AOR 4AOR 4AOR 4AOR Glotzbach et al., 2013
mature  peptidase 1.78 Å 4B1T 4B1T 4B1T 4B1T 4B1T 4B1T Menzel et al., 2014
mature  peptidase 1.89 Å 4B2A 4B2A 4B2A 4B2A 4B2A 4B2A Menzel et al., 2014
mature  peptidase 1.36 Å 4B2B 4B2B 4B2B 4B2B 4B2B 4B2B Menzel et al., 2014
mature  peptidase 1.43 Å 4B2C 4B2C 4B2C 4B2C 4B2C 4B2C Menzel et al., 2014
mature  peptidase 1.80 Å 4GUX 4GUX 4GUX 4GUX 4GUX 4GUX
mature  peptidase 1.29 Å 4HGC 4HGC 4HGC 4HGC 4HGC 4HGC Krzywda et al., 2014
mature  peptidase 0.80 Å 4I8G 4I8G 4I8G 4I8G 4I8G 4I8G Liebschner et al., 2013
mature  peptidase 0.75 Å 4I8H 4I8H 4I8H 4I8H 4I8H 4I8H Liebschner et al., 2013
mature  peptidase 0.87 Å 4I8J 4I8J 4I8J 4I8J 4I8J 4I8J Liebschner et al., 2013
mature  peptidase 0.85 Å 4I8K 4I8K 4I8K 4I8K 4I8K 4I8K Liebschner et al., 2013
mature  peptidase 0.87 Å 4I8L 4I8L 4I8L 4I8L 4I8L 4I8L Liebschner et al., 2013
mature  peptidase 2.00 Å 4J2Y 4J2Y 4J2Y 4J2Y 4J2Y 4J2Y Zhou et al., 2013
mature  peptidase 1.30 Å 4KTS 4KTS 4KTS 4KTS 4KTS 4KTS Weiz et al., 2014
mature  peptidase 1.35 Å 4KTU 4KTU 4KTU 4KTU 4KTU 4KTU Weiz et al., 2014
mature  peptidase 1.22 Å 4MTB 4MTB 4MTB 4MTB 4MTB 4MTB
mature  peptidase 1.42 Å 4NCY 4NCY 4NCY 4NCY 4NCY 4NCY Yin et al., 2014
mature  peptidase 1.00 Å 4NIV 4NIV 4NIV 4NIV 4NIV 4NIV Liebscher et al., 2014
mature  peptidase 1.31 Å 4NIW 4NIW 4NIW 4NIW 4NIW 4NIW Liebscher et al., 2014
mature  peptidase 1.30 Å 4NIX 4NIX 4NIX 4NIX 4NIX 4NIX Liebscher et al., 2014
mature  peptidase 2.84 Å 4NIY 4NIY 4NIY 4NIY 4NIY 4NIY Liebscher et al., 2014
beta-trypsin; complex with diisopropylphosphoryl 1.34 Å 4PTP 4PTP 4PTP 4PTP 4PTP 4PTP Finer-Moore et al., 1992
precursor; complex with pancreatic trypsin inhibitor Arg15 analogue 2.20 Å 4TPI 4TPI 4TPI 4TPI 4TPI 4TPI Bode et al., 1984
mature  peptidase 1.30 Å 4TPY 4TPY 4TPY 4TPY 4TPY 4TPY Teplitsky et al., 2015
complex with inhibitor (Huia versabilis) 1.00 Å 4U2W 4U2W 4U2W 4U2W 4U2W 4U2W Grudnik et al., 2015
mature  peptidase 0.91 Å 4XOJ 4XOJ 4XOJ 4XOJ 4XOJ 4XOJ Karna et al., 2015
mature  peptidase 1.25 Å 4Y0Y 4Y0Y 4Y0Y 4Y0Y 4Y0Y 4Y0Y
mature  peptidase 1.37 Å 4Y0Z 4Y0Z 4Y0Z 4Y0Z 4Y0Z 4Y0Z
mature  peptidase 1.37 Å 4Y10 4Y10 4Y10 4Y10 4Y10 4Y10
mature  peptidase 1.30 Å 4Y11 4Y11 4Y11 4Y11 4Y11 4Y11
mature  peptidase 1.20 Å 4YTA 4YTA 4YTA 4YTA 4YTA 4YTA Fisher et al., 2012
complex with cyclic inhibitor 1.32 Å 5EG4 5EG4 5EG4 5EG4 5EG4 5EG4
model for comparison of diffuse scattering 1.10 Å 5F6M 5F6M 5F6M 5F6M 5F6M 5F6M
solved by mr from data collected by direct data collection (ddc) using the esrf robodiff goniometer 1.78 Å 5FXL 5FXL 5FXL 5FXL 5FXL 5FXL
succinic acid bound trypsin crystallized as dimer 2.70 Å 5GIB 5GIB 5GIB 5GIB 5GIB 5GIB
cationic trypsin with gol/pge as dimer at ph 4.6 2.80 Å 5GXP 5GXP 5GXP 5GXP 5GXP 5GXP
complex with succinic acid 1.91 Å 5JYI 5JYI 5JYI 5JYI 5JYI 5JYI
mature  peptidase 1.70 Å 5K7R 5K7R 5K7R 5K7R 5K7R 5K7R
trypsin inhibitors for the treatment of pancreatitis - cpd 15 1.12 Å 5LGO 5LGO 5LGO 5LGO 5LGO 5LGO
trypsin inhibitors for the treatment of pancreatitis - cpd 1 1.37 Å 5LH4 5LH4 5LH4 5LH4 5LH4 5LH4
trypsin inhibitors for the treatment of pancreatitis - cpd 8 1.54 Å 5LH8 5LH8 5LH8 5LH8 5LH8 5LH8
complex with 2-aminopyridine (deuterated sample at100 k) 0.79 Å 5MN1 5MN1 5MN1 5MN1 5MN1 5MN1
complex with aniline (deuterated sample at 295 k) 1.44 Å 5MNA 5MNA 5MNA 5MNA 5MNA 5MNA
complex with 2-aminopyridine (deuterated sample at295 k) 0.94 Å 5MNB 5MNB 5MNB 5MNB 5MNB 5MNB
complex with aniline (deuterated sample at 100 k) 0.92 Å 5MNC 5MNC 5MNC 5MNC 5MNC 5MNC
cationic trypsin in its apo form (deuterated sample at 100 k) 1.01 Å 5MNE 5MNE 5MNE 5MNE 5MNE 5MNE
cationic trypsin in its apo form (deuterated sample at 295 k) 0.99 Å 5MNF 5MNF 5MNF 5MNF 5MNF 5MNF
complex with benzamidine (deuterated sample at 100k) 0.86 Å 5MNG 5MNG 5MNG 5MNG 5MNG 5MNG
complex with benzamidine (deuterated sample at 295k) 0.93 Å 5MNH 5MNH 5MNH 5MNH 5MNH 5MNH
complex with benzylamine (deuterated sample at 100k) 0.80 Å 5MNK 5MNK 5MNK 5MNK 5MNK 5MNK
complex with benzylamine (deuterated sample at 295k) 1.04 Å 5MNL 5MNL 5MNL 5MNL 5MNL 5MNL
complex with benzylamine (at 295 k) 0.98 Å 5MNM 5MNM 5MNM 5MNM 5MNM 5MNM
complex with n-amidinopiperidine (deuterated sample at 100 k) 0.86 Å 5MNN 5MNN 5MNN 5MNN 5MNN 5MNN
complex with n-amidinopiperidine (deuterated sample at 295 k) 0.96 Å 5MNO 5MNO 5MNO 5MNO 5MNO 5MNO
complex with n-amidinopiperidine (at 295 k) 1.01 Å 5MNP 5MNP 5MNP 5MNP 5MNP 5MNP
complex with a derivative of n-amidinopiperidine 1.34 Å 5MNQ 5MNQ 5MNQ 5MNQ 5MNQ 5MNQ
complex with 2-aminopyridine 1.42 Å 5MNX 5MNX 5MNX 5MNX 5MNX 5MNX
complex with aniline 1.43 Å 5MNY 5MNY 5MNY 5MNY 5MNY 5MNY
neutron structure of cationic trypsin in its apo form 1.45 Å 5MNZ 5MNZ 5MNZ 5MNZ 5MNZ 5MNZ
complex with benzamidine 1.50 Å 5MO0 5MO0 5MO0 5MO0 5MO0 5MO0
complex with benzylamine 1.49 Å 5MO1 5MO1 5MO1 5MO1 5MO1 5MO1
complex with n- amidinopiperidine 1.50 Å 5MO2 5MO2 5MO2 5MO2 5MO2 5MO2
complex with 2- aminopyridine 0.94 Å 5MON 5MON 5MON 5MON 5MON 5MON
complex with aniline 1.44 Å 5MOO 5MOO 5MOO 5MOO 5MOO 5MOO
apo form 0.99 Å 5MOP 5MOP 5MOP 5MOP 5MOP 5MOP
complex with benzamidine 0.93 Å 5MOQ 5MOQ 5MOQ 5MOQ 5MOQ 5MOQ
complex with benzylamine 0.98 Å 5MOR 5MOR 5MOR 5MOR 5MOR 5MOR
complex with n- amidinopiperidine 0.96 Å 5MOS 5MOS 5MOS 5MOS 5MOS 5MOS
beta-trypsin 1.34 Å 5PTP 5PTP 5PTP 5PTP 5PTP 5PTP Finer-Moore et al., 1992
soaked with selenourea for 5 min 1.55 Å 5T3H 5T3H 5T3H 5T3H 5T3H 5T3H
orthorhombic trypsin (295 k) in the presence of 50% xylose 2.00 Å 6AVL 6AVL 6AVL 6AVL 6AVL 6AVL
orthorhombic trypsin (295 k) in the presence of 50% mpd 2.00 Å 6B6N 6B6N 6B6N 6B6N 6B6N 6B6N
orthorhombic trypsin cryocooled to 100 k with 20% xylose as cryoprotectant 2.40 Å 6B6O 6B6O 6B6O 6B6O 6B6O 6B6O
orthorhombic trypsin cryocooled to 100 k with 30% xylose as cryoprotectant 2.00 Å 6B6P 6B6P 6B6P 6B6P 6B6P 6B6P
orthorhombic trypsin cryocooled to 100 k with 50% xylose as cryoprotectant 2.00 Å 6B6Q 6B6Q 6B6Q 6B6Q 6B6Q 6B6Q
orthorhombic trypsin cryocooled to 100 k with 50% mpd as cryoprotectant 2.00 Å 6B6R 6B6R 6B6R 6B6R 6B6R 6B6R
orthorhombic trypsin cryocooled to 100 k with 50% ethanol as cryoprotectant 2.00 Å 6B6S 6B6S 6B6S 6B6S 6B6S 6B6S
orthorhombic trypsin cryocooled to 100 k with 50% methanol as cryoprotectant 2.00 Å 6B6T 6B6T 6B6T 6B6T 6B6T 6B6T
complex with potent inhibitor 1.29 Å 6BFP 6BFP 6BFP 6BFP 6BFP 6BFP
complex with a modified sunflower trypsin inhibitor, sfti- tctr(n12,n14) 1.93 Å 6BVH 6BVH 6BVH 6BVH 6BVH 6BVH
complex with BBKI Leu55Arg mutant 1.94 Å 6DWF 6DWF 6DWF 6DWF 6DWF 6DWF
complex with BBKI 2.00 Å 6DWH 6DWH 6DWH 6DWH 6DWH 6DWH
complex with cyanobenzylsulfonylfluoride 1.32 Å 6DWR 6DWR 6DWR 6DWR 6DWR 6DWR
orthorhombic trypsin cryocooled to 100 k with 20% xylose as cryoprotectant 2.20 Å 6DZF 6DZF 6DZF 6DZF 6DZF 6DZF
crystallographic structure of the cyclic nonapeptide derived from the btci inhibitor bound to beta-trypsin in space group p 32 2 1 1.61 Å 6E5M 6E5M 6E5M 6E5M 6E5M 6E5M
crystallographic structure of the cyclic nonapeptide derived from the btci inhibitor bound to beta-trypsin in space group p 21 21 21. 1.15 Å 6EAT 6EAT 6EAT 6EAT 6EAT 6EAT
mature  peptidase 2.20 Å 6FID 6FID 6FID 6FID 6FID 6FID
Sus scrofa
first active autolysate form 1.80 Å 1AKS 1AKS 1AKS 1AKS 1AKS 1AKS Johnson et al., 1997
complex with leech-derived tryptase inhibitor 2.03 Å 1AN1 1AN1 1AN1 1AN1 1AN1 1AN1 Di & Priestle, 1997
orthorhombic crystal form, complex with soybean trypsin inhibitor 1.75 Å 1AVW 1AVW 1AVW 1AVW 1AVW 1AVW Song & Suh, 1998
tetragonal crystal form, complex with soybean trypsin inhibitor 1.90 Å 1AVX 1AVX 1AVX 1AVX 1AVX 1AVX Song & Suh, 1998
complex with bdellastasin 2.80 Å 1C9P 1C9P 1C9P 1C9P 1C9P 1C9P Rester et al., 1999
theoretical model; complex with inhibitor MCTI-A (Cucurbita maxima) 0.00 Å 1D3O 1D3O 1D3O 1D3O 1D3O 1D3O
theoretical model; complex with (Luffa acutangula) inhibitor 0.00 Å 1DF2 1DF2 1DF2 1DF2 1DF2 1DF2
complex with bdellastasin 2.70 Å 1EJA 1EJA 1EJA 1EJA 1EJA 1EJA Rester et al., 2000
mature  peptidase 1.80 Å 1EPT 1EPT 1EPT 1EPT 1EPT 1EPT Huang et al., 1994
mature  peptidase 0.00 Å 1EWU 1EWU 1EWU 1EWU 1EWU 1EWU
in 0.04% polydocanol 1.90 Å 1FMG 1FMG 1FMG 1FMG 1FMG 1FMG Deepthi et al., 2001
in 0.1% polydocanol 1.80 Å 1FN6 1FN6 1FN6 1FN6 1FN6 1FN6 Deepthi et al., 2001
in 0.01% polydocanol 1.60 Å 1FNI 1FNI 1FNI 1FNI 1FNI 1FNI Deepthi et al., 2001
complex with EETI-II 1.50 Å 1H9H 1H9H 1H9H 1H9H 1H9H 1H9H Kratzner et al., 2005
complex with EETI-II mutant 1.90 Å 1H9I 1H9I 1H9I 1H9I 1H9I 1H9I Kratzner et al., 2005
complex with a leech-derived tryptase inhibitor 1.90 Å 1LDT 1LDT 1LDT 1LDT 1LDT 1LDT Stubbs et al., 1997
theoretical model; complex with Leucaena leucocephala trypsin inhibitor alpha and beta chains 0.00 Å 1LT2 1LT2 1LT2 1LT2 1LT2 1LT2
complex with bitter gourd inhibitor 1.60 Å 1MCT 1MCT 1MCT 1MCT 1MCT 1MCT Huang et al., 1993
with bound acetate 1.63 Å 1QQU 1QQU 1QQU 1QQU 1QQU 1QQU Johnson et al., 1999
complex with turkey ovomucoid second domain 1.90 Å 1R0T 1R0T 1R0T 1R0T 1R0T 1R0T Ibrahim & Pattabhi, 2004
complex with guanidine-3-propanol inhibitor 1.40 Å 1S5S 1S5S 1S5S 1S5S 1S5S 1S5S Transue et al., 2004
complex with borate and guanidine-3 inhibitor 1.80 Å 1S6F 1S6F 1S6F 1S6F 1S6F 1S6F Transue et al., 2004
complex with guanidine-3-propanol inhibitor 1.45 Å 1S6H 1S6H 1S6H 1S6H 1S6H 1S6H Transue et al., 2004
mature  peptidase 1.70 Å 1S81 1S81 1S81 1S81 1S81 1S81 Transue et al., 2004
complex with borate and ethylene glycol 1.85 Å 1S82 1S82 1S82 1S82 1S82 1S82 Transue et al., 2004
complex with 4-amino propanol 1.25 Å 1S83 1S83 1S83 1S83 1S83 1S83 Transue et al., 2004
complex with 4-amino butanol, borate and ethylene glycol 1.85 Å 1S84 1S84 1S84 1S84 1S84 1S84 Transue et al., 2004
complex with p-hydroxymethyl benzamidine and borate 2.20 Å 1S85 1S85 1S85 1S85 1S85 1S85 Transue et al., 2004
complex with the second domain of tissue factor pathway inhibitor 2.60 Å 1TFX 1TFX 1TFX 1TFX 1TFX 1TFX Burgering et al., 1997
complex with barley Bowman-Birk inhibitor 2.20 Å 1TX6 1TX6 1TX6 1TX6 1TX6 1TX6 Park et al., 2004
complex with auto catalyticaly produced native peptide 2.15 Å 1UHB 1UHB 1UHB 1UHB 1UHB 1UHB Ibrahim et al., 2004
complex with synthetic heterochiral peptide 1.90 Å 1V6D 1V6D 1V6D 1V6D 1V6D 1V6D Shamaladevi & Pattabhi, 2005
complex with vasopressin 1.98 Å 1YF4 1YF4 1YF4 1YF4 1YF4 1YF4 Syed & Pattabhi, 2005
complex with ovomucoid turkey egg white inhibitor 1.90 Å 1Z7K 1Z7K 1Z7K 1Z7K 1Z7K 1Z7K Ibrahim & Pattabhi, 2004
complex with borate 1.25 Å 2A31 2A31 2A31 2A31 2A31 2A31 Transue et al., 2006
complex with benzene boronic acid 1.50 Å 2A32 2A32 2A32 2A32 2A32 2A32 Transue et al., 2006