Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P49913

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
30	unknown peptidase	1-170	P		NT	<%Agarwal et al., 2012[]%>
131	unknown peptidase	1-170	P		NT	<%Agarwal et al., 2012[]%>
133	kallikrein-related peptidase 5	1-170	P			Yamasaki et al., 2006
133	elastase-2	31-170	P			Sorensen et al., 2001
133	myeloblastin	31-170	P			Sorensen et al., 2001
134	mirabilysin	134-170	P			Belas et al., 2004
136	mirabilysin	134-170	P			Belas et al., 2004
138	cathepsin D	31-170	P	normal turnover		Baechle et al., 2006
138	mirabilysin	134-170	P			Belas et al., 2004
138	kallikrein-related peptidase 7	134-170	P			Yamasaki et al., 2006
139	kallikrein-related peptidase 7	134-170	P			Yamasaki et al., 2006
140	kallikrein-related peptidase 5	134-170	P			Yamasaki et al., 2006
141	mirabilysin	134-170	P			Belas et al., 2004
142	mirabilysin	134-170	P			Belas et al., 2004
144	glutamyl endopeptidase I	134-170	P			Sieprawska-Lupa et al., 2004
145	pseudolysin	132-170	N			Schmidtchen et al.,2002
149	pseudolysin	132-170	N			Schmidtchen et al.,2002
149	mirabilysin	134-170	P			Belas et al., 2004
149	glutamyl endopeptidase I	134-170	P			Sieprawska-Lupa et al., 2004
150	mirabilysin	134-170	P			Belas et al., 2004
150	kallikrein-related peptidase 7	134-170	P			Yamasaki et al., 2006
152	pseudolysin	132-170	N			Schmidtchen et al.,2002
152	aureolysin	134-170	N			Sieprawska-Lupa et al., 2004
152	mirabilysin	134-170	P			Belas et al., 2004
152	kallikrein-related peptidase 5	134-170	P			Yamasaki et al., 2006
153	mirabilysin	134-170	P			Belas et al., 2004
154	mirabilysin	134-170	P			Belas et al., 2004
155	mirabilysin	134-170	P			Belas et al., 2004
156	pseudolysin	132-170	N			Schmidtchen et al.,2002
156	aureolysin	134-170	N			Sieprawska-Lupa et al., 2004
156	mirabilysin	134-170	P			Belas et al., 2004
156	kallikrein-related peptidase 5	134-170	P			Yamasaki et al., 2006
157	mirabilysin	134-170	P			Belas et al., 2004
158	mirabilysin	134-170	P			Belas et al., 2004
159	pseudolysin	132-170	N			Schmidtchen et al.,2002
159	mirabilysin	134-170	P			Belas et al., 2004
160	cathepsin D	31-170	P	normal turnover		Baechle et al., 2006
160	mirabilysin	134-170	P			Belas et al., 2004
160	kallikrein-related peptidase 7	134-170	P			Yamasaki et al., 2006
162	mirabilysin	134-170	P			Belas et al., 2004
162	kallikrein-related peptidase 5	134-170	P			Yamasaki et al., 2006
163	pseudolysin	132-170	N			Schmidtchen et al.,2002
163	mirabilysin	134-170	P			Belas et al., 2004
164	aureolysin	134-170	N			Sieprawska-Lupa et al., 2004
164	mirabilysin	134-170	P			Belas et al., 2004
167	kallikrein-related peptidase 5	134-170	P			Yamasaki et al., 2006
169	mirabilysin	134-170	P			Belas et al., 2004