Substrates for peptidase M10.057: mirabilysin

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Abz-Ala-Phe-Arg-Ser-Ala-Ala-Gln-EDDnp Abz-Ala-Phe-Arg+Ser-Ala-Ala-Gln-EDDnp S Abz Ala Phe Arg Ser Ala Ala Gln Belas, 2004
Abz-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-Gln-EDDnp Abz-Arg-Pro-Pro-Gly-Phe+Ser-Pro-Phe-Arg-Gln-EDDnp S Pro Pro Gly Phe Ser Pro Phe Arg Belas, 2004
cathelicidin antimicrobial peptide P49913 134-170 peptide-Leu134+Leu-peptide P - - - Leu Leu Gly Asp Phe Belas et al., 2004 23086
cathelicidin antimicrobial peptide P49913 134-170 peptide-Phe138+Phe-peptide P Leu Gly Asp Phe Phe Arg Lys Ser Belas et al., 2004 23087
cathelicidin antimicrobial peptide P49913 134-170 peptide-Glu149+Phe-peptide P Ile Gly Lys Glu Phe Lys Arg Ile Belas et al., 2004 23088
cathelicidin antimicrobial peptide P49913 134-170 peptide-Arg152+Ile-peptide P Glu Phe Lys Arg Ile Val Gln Arg Belas et al., 2004 23089
cathelicidin antimicrobial peptide P49913 134-170 peptide-Lys141+Ser-peptide P Phe Phe Arg Lys Ser Lys Glu Lys Belas et al., 2004 23091
cathelicidin antimicrobial peptide P49913 134-170 peptide-Phe150+Lys-peptide P Gly Lys Glu Phe Lys Arg Ile Val Belas et al., 2004 23092
cathelicidin antimicrobial peptide P49913 134-170 peptide-Val154+Gln-peptide P Lys Arg Ile Val Gln Arg Ile Lys Belas et al., 2004 23093
cathelicidin antimicrobial peptide P49913 134-170 peptide-Ser142+Lys-peptide P Phe Arg Lys Ser Lys Glu Lys Ile Belas et al., 2004 23104
cathelicidin antimicrobial peptide P49913 134-170 peptide-Arg156+Ile-peptide P Ile Val Gln Arg Ile Lys Asp Phe Belas et al., 2004 23094
cathelicidin antimicrobial peptide P49913 134-170 peptide-Ile153+Val-peptide P Phe Lys Arg Ile Val Gln Arg Ile Belas et al., 2004 23095
cathelicidin antimicrobial peptide P49913 134-170 peptide-Ile157+Lys-peptide P Val Gln Arg Ile Lys Asp Phe Leu Belas et al., 2004 23096
cathelicidin antimicrobial peptide P49913 134-170 peptide-Phe160+Leu-peptide P Ile Lys Asp Phe Leu Arg Asn Leu Belas et al., 2004 23097
cathelicidin antimicrobial peptide P49913 134-170 peptide-Leu164+Val-peptide P Leu Arg Asn Leu Val Pro Arg Thr Belas et al., 2004 23098
cathelicidin antimicrobial peptide P49913 134-170 peptide-Lys158+Asp-peptide P Gln Arg Ile Lys Asp Phe Leu Arg Belas et al., 2004 23099
cathelicidin antimicrobial peptide P49913 134-170 peptide-Arg162+Asn-peptide P Asp Phe Leu Arg Asn Leu Val Pro Belas et al., 2004 23100
cathelicidin antimicrobial peptide P49913 134-170 peptide-Asp159+Phe-peptide P Arg Ile Lys Asp Phe Leu Arg Asn Belas et al., 2004 23101
cathelicidin antimicrobial peptide P49913 134-170 peptide-Asn159+Leu-peptide P Phe Leu Arg Asn Leu Val Pro Arg Belas et al., 2004 23102
cathelicidin antimicrobial peptide P49913 134-170 peptide-Gly136+Asp-peptide P - Leu Leu Gly Asp Phe Phe Arg Belas et al., 2004 23103
cathelicidin antimicrobial peptide P49913 134-170 peptide-Gln155+Arg-peptide P Arg Ile Val Gln Arg Ile Lys Asp Belas et al., 2004
cathelicidin antimicrobial peptide P49913 134-170 peptide-Glu169+Ser-peptide P Pro Arg Thr Glu Ser - - - Belas et al., 2004
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Gly57+Thr-peptide P Lys Ile Gln Gly Thr Cys Tyr Arg Belas et al., 2004 23105
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Arg61+Gly-peptide P Thr Cys Tyr Arg Gly Lys Ala Lys Belas et al., 2004 23106
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Cys49+Pro-peptide P Tyr Ser Ala Cys Pro Ile Phe Thr Belas et al., 2004 23107
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Gln56+Gly-peptide P Thr Lys Ile Gln Gly Thr Cys Tyr Belas et al., 2004 23108
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Ile51+Phe-peptide P Ala Cys Pro Ile Phe Thr Lys Ile Belas et al., 2004 23109
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Tyr60+Arg-peptide P Gly Thr Cys Tyr Arg Gly Lys Ala Belas et al., 2004 23110
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Val38+Ser-peptide P Tyr Asn Cys Val Ser Ser Gly Gly Belas et al., 2004 23111
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Cys66+Cys-peptide P Lys Ala Lys Cys Cys Lys Gly Gly Belas et al., 2004 23113
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Ala48+Cys-peptide P Leu Tyr Ser Ala Cys Pro Ile Phe Belas et al., 2004 23115
DEFB1 defensin, beta 1 preproprotein P60022 33-68 peptide-Pro50+Ile-peptide P Ser Ala Cys Pro Ile Phe Thr Lys Belas et al., 2004 23116