Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P00742

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
31	unknown peptidase	1-488	P		NT	<%Agarwal et al., 2012[]%>
40	unknown peptidase	1-488	P		NT	<%Agarwal et al., 2012[]%>
179	carboxypeptidase B2	41-488	P			Brown et al., 2004
180	carboxypeptidase B2	41-488	P			Brown et al., 2004
181	carboxypeptidase B2	41-488	P			Brown et al., 2004
182	unknown peptidase	1-488	P		NT	<%Agarwal et al., 2012[]%>
203	cancer procoagulant	183-488	N			Gordon & Mielicki, 2004
215	cathepsin G	41-488	P		NT	Plescia & Altieri, 1996
216	thermolysin	41-488	N			Narasaki et al., 2005
217	cathepsin G	32-488	P			Brown et al., 2004
227	gingipain RgpA	41-488	N		CS	Imamura et al., 1997
227	gingipain RgpB	41-488	P		CS	Imamura et al., 1997
234	gingipain RgpA	41-488	N		CS	Imamura et al., 1997
234	gingipain RgpB	41-488	P		CS	Imamura et al., 1997
234	thermolysin	41-488	N			Narasaki et al., 2005
234	russellysin	230-238	N		MS	Siigur et al., 2001
234	coagulation factor IXa	32-488	P
234	coagulation factor VIIa	32-488	P
234	kallikrein-related peptidase 4	1-488	P		CS	Matsumura et al., 2005
234	cerastotin	32-488	N			Marrakchi et al., 1997
234	afaacytin (Cerastes cerastes)	32-488	N			Laraba-Djebari et al., 1995
234	snake venom coagulation factor X activator, serine-type (Bungarus fasciatus, Cerastes vipera, Ophiophagus hannah)	32-488	P			Brown et al., 2004
335	plasmin	41-488	P			Pryzdial et al., 1999
370	plasmin	41-179; 235-488	P			Pryzdial et al., 1999
372	coagulation factor Xa	41-179; 183-488	P			Brandstetter et al., 1996
469	gingipain RgpA	41-488	N		CS	Imamura et al., 1997
469	gingipain RgpB	41-488	P		CS	Imamura et al., 1997