Substrates for peptidase S9G.025: snake venom coagulation factor X activator, serine-type (Bungarus fasciatus, Cerastes vipera, Ophiophagus hannah)

Summary Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
coagulation factor X	P00742	32-488	peptide-Arg152+Ile-peptide	P	Asn	Leu	Thr	Arg	Ile	Val	Gly	Gly	Brown et al., 2004	17680
plasminogen	P00747	20-810	peptide-Arg561+Val-peptide	P	Cys	Pro	Gly	Arg	Val	Val	Gly	Gly	Zhang et al., 1995	17681
S-2238			D-Phe-Pip-Arg+NHPhNO2	S	-	DPh	Pip	Arg	NAN	-	-	-	Zhang et al., 1995
S-2251			D-Val-Leu-Lys+NHPhNO2	S	-	DVa	Leu	Lys	NAN	-	-	-	Zhang et al., 1995
S-2302			D-Pro-Phe-Arg+NHPhNO2	S	-	DPr	Phe	Arg	NAN	-	-	-	Zhang et al., 1995
S-2444			D-Glu-Gly-Arg+NHPhNO2	S	-	DGl	Gly	Arg	NAN	-	-	-	Zhang et al., 1995