CHEBI:16643 - L-methionine

ChEBI IDCHEBI:16643
ChEBI NameL-methionine
Stars
ASCII NameL-methionine
DefinitionThe L-enantiomer of methionine.
Secondary ChEBI IDsCHEBI:6271, CHEBI:13141, CHEBI:21360, CHEBI:43990
Last Modified18 May 2022
DownloadsMolfile
FormulaC5H11NO2S
Net Charge0
Average Mass149.215
Monoisotopic Mass149.05105
SMILESCSCC[C@H](N)C(=O)O
InChIInChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKeyFFEARJCKVFRZRR-BYPYZUCNSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - DOI (10.1038/nbt.2488)
Saccharomyces cerevisiae (ncbitaxon:4932)
- PubMed (5764336)
- PubMed (24678285) Source: yeast.sf.net
Escherichia coli (ncbitaxon:562)
- PubMed (24939187)
- PubMed (21988831)
Mus musculus (ncbitaxon:10090) - PubMed (19425150) Source: BioModels - MODEL1507180067
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
mouse metabolite  Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
micronutrient  Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Daphnia magna metabolite  A Daphnia metabolite produced by the species Daphnia magna.
plant metabolite  Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
algal metabolite  Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
Saccharomyces cerevisiae metabolite  Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
Escherichia coli metabolite  Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Applications:
antidote to paracetamol poisoning  A role borne by a molecule that acts to counteract or neutralize the deleterious effects of paracetamol (acetaminophen).
nutraceutical  A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
ChEBI Ontology
Outgoing Relation(s)
L-methionine (CHEBI:16643) has role antidote to paracetamol poisoning (CHEBI:74529)
L-methionine (CHEBI:16643) has role human metabolite (CHEBI:77746)
L-methionine (CHEBI:16643) has role micronutrient (CHEBI:27027)
L-methionine (CHEBI:16643) has role mouse metabolite (CHEBI:75771)
L-methionine (CHEBI:16643) has role nutraceutical (CHEBI:50733)
L-methionine (CHEBI:16643) is a L-α-amino acid (CHEBI:15705)
L-methionine (CHEBI:16643) is a aspartate family amino acid (CHEBI:22658)
L-methionine (CHEBI:16643) is a methionine (CHEBI:16811)
L-methionine (CHEBI:16643) is a proteinogenic amino acid (CHEBI:83813)
L-methionine (CHEBI:16643) is conjugate acid of L-methioninate (CHEBI:32631)
L-methionine (CHEBI:16643) is conjugate base of L-methioninium (CHEBI:32632)
L-methionine (CHEBI:16643) is enantiomer of D-methionine (CHEBI:16867)
L-methionine (CHEBI:16643) is tautomer of L-methionine zwitterion (CHEBI:57844)
Incoming Relation(s)
(S)-5-[2-(methylthio)ethyl]hydantoin (CHEBI:137117) has functional parent L-methionine (CHEBI:16643)
L-methionine derivative (CHEBI:84121) has functional parent L-methionine (CHEBI:16643)
4-methylthio-2-oxobutanoic acid (CHEBI:33574) has functional parent L-methionine (CHEBI:16643)
Ala-Met-Asp-Tyr (CHEBI:176849) has functional parent L-methionine (CHEBI:16643)
Ala-Met-Gln-Gln (CHEBI:137239) has functional parent L-methionine (CHEBI:16643)
Ala-Met-Ser-Arg (CHEBI:73376) has functional parent L-methionine (CHEBI:16643)
Asn-Met (CHEBI:141423) has functional parent L-methionine (CHEBI:16643)
Asn-Met-Gln-Pro (CHEBI:138505) has functional parent L-methionine (CHEBI:16643)
Asn-Met-Thr-Thr (CHEBI:138506) has functional parent L-methionine (CHEBI:16643)
Asn-Met-Trp-Asn (CHEBI:73412) has functional parent L-methionine (CHEBI:16643)
Asp-Met (CHEBI:141426) has functional parent L-methionine (CHEBI:16643)
Asp-Met-Met-Cys (CHEBI:176848) has functional parent L-methionine (CHEBI:16643)
Asp-Met-Thr-Pro (CHEBI:73436) has functional parent L-methionine (CHEBI:16643)
Cys-Met-Gln (CHEBI:144427) has functional parent L-methionine (CHEBI:16643)
Cys-Met-Met-Met (CHEBI:73457) has functional parent L-methionine (CHEBI:16643)
Cys-Met-Phe-His (CHEBI:138508) has functional parent L-methionine (CHEBI:16643)
Cys-Met-Thr-Tyr (CHEBI:73459) has functional parent L-methionine (CHEBI:16643)
Glu-Arg-Gly-Met (CHEBI:191942) has functional parent L-methionine (CHEBI:16643)
Glu-Arg-Gly-Met-Thr (CHEBI:191943) has functional parent L-methionine (CHEBI:16643)
Glu-Met (CHEBI:73507) has functional parent L-methionine (CHEBI:16643)
Leu-Met (CHEBI:73584) has functional parent L-methionine (CHEBI:16643)
Lys-Met-Met-Met (CHEBI:73595) has functional parent L-methionine (CHEBI:16643)
Met-Ala (CHEBI:73610) has functional parent L-methionine (CHEBI:16643)
Met-Ala-Asp (CHEBI:73609) has functional parent L-methionine (CHEBI:16643)
Met-Ala-Met (CHEBI:140747) has functional parent L-methionine (CHEBI:16643)
Met-Asn (CHEBI:141442) has functional parent L-methionine (CHEBI:16643)
Met-enkephalin (CHEBI:6618) has functional parent L-methionine (CHEBI:16643)
Met-FMDP (CHEBI:74356) has functional parent L-methionine (CHEBI:16643)
Met-Gly (CHEBI:73611) has functional parent L-methionine (CHEBI:16643)
Met-Met (CHEBI:74707) has functional parent L-methionine (CHEBI:16643)
Met-Phe-Met (CHEBI:160990) has functional parent L-methionine (CHEBI:16643)
Met-Pro (CHEBI:73612) has functional parent L-methionine (CHEBI:16643)
Met-Ser (CHEBI:73613) has functional parent L-methionine (CHEBI:16643)
Met-Thr (CHEBI:73614) has functional parent L-methionine (CHEBI:16643)
Met-Tyr (CHEBI:73615) has functional parent L-methionine (CHEBI:16643)
Met-Val (CHEBI:73616) has functional parent L-methionine (CHEBI:16643)
Pro-Met (CHEBI:141444) has functional parent L-methionine (CHEBI:16643)
γ-Glu-Met (CHEBI:82965) has functional parent L-methionine (CHEBI:16643)
L-methionine-d3 (CHEBI:192080) is a L-methionine (CHEBI:16643)
L-methioninium (CHEBI:32632) is conjugate acid of L-methionine (CHEBI:16643)
L-methioninate (CHEBI:32631) is conjugate base of L-methionine (CHEBI:16643)
D-methionine (CHEBI:16867) is enantiomer of L-methionine (CHEBI:16643)
L-methionine residue (CHEBI:16044) is substituent group from L-methionine (CHEBI:16643)
L-methionino group (CHEBI:49037) is substituent group from L-methionine (CHEBI:16643)
L-methionyl group (CHEBI:49038) is substituent group from L-methionine (CHEBI:16643)
L-methionine zwitterion (CHEBI:57844) is tautomer of L-methionine (CHEBI:16643)
IUPAC Name 
L-methionine
Synonyms  Source
L-MethionineKEGG COMPOUND
MChEBI
MetChEBI
(2S)-2-amino-4-(methylsulfanyl)butanoic acidIUPAC
L-(−)-methionineNIST Chemistry WebBook
(S)-methionineChEBI
Manual XrefsDatabases
C00073KEGG COMPOUND
MET_LFOHPDBeChem
D00019KEGG DRUG
DB00134DrugBank
HMDB0000696HMDB
METMetaCyc
YMDB00318YMDB
ECMDB00696ECMDB
C00001379KNApSAcK
3347DrugCentral
Registry NumbersSources
Gmelin:26935Gmelin
Reaxys:1722294Reaxys
CAS:63-68-3KEGG COMPOUND
CAS:63-68-3ChemIDplus
CAS:63-68-3NIST Chemistry WebBook
Citations