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Substrates for peptidase C01.101: cathepsin B-like peptidase, nematode

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
hemoglobin subunit alpha P69905 2-142 peptide-Ala13+Ala-peptide N MS Asn Val Lys Ala Ala Trp Gly Lys Ranjit et al., 2009 24558
hemoglobin subunit alpha P69905 2-142 peptide-Leu30+Glu-peptide N MS Ala Glu Ala Leu Glu Arg Met Phe Ranjit et al., 2009 24559
hemoglobin subunit alpha P69905 2-142 peptide-Phe37+Pro-peptide N MS Phe Leu Ser Phe Pro Thr Thr Lys Ranjit et al., 2009 24560
hemoglobin subunit alpha P69905 2-142 peptide-Arg93+Val-peptide N MS His Lys Leu Arg Val Asp Pro Val Ranjit et al., 2009 24561
Hemoglobin subunit alpha P69905 peptide-Ala13+Ala-peptide P MS Asn Val Lys Ala Ala Trp Gly Lys Ranjit et al., 2009 24562
Hemoglobin subunit alpha P69905 peptide-Leu30+Glu-peptide P MS Ala Glu Ala Leu Glu Arg Met Phe Ranjit et al., 2009 24563
Hemoglobin subunit alpha P69905 peptide-Arg93+Val-peptide P MS His Lys Leu Arg Val Asp Pro Val Ranjit et al., 2009 24564
Hemoglobin subunit alpha P69905 peptide-Phe37+Pro-peptide P MS Phe Leu Ser Phe Pro Thr Thr Lys Ranjit et al., 2009 24565
hemoglobin subunit alpha P60529 1-141 peptide-Ser12+Thr-peptide N MS Asn Ile Lys Ser Thr Trp Asp Lys Williamson et al., 2004 24611
hemoglobin subunit alpha P60529 1-141 peptide-Gly18+Gly-peptide N MS Asp Lys Ile Gly Gly His Ala Gly Williamson et al., 2004 24612
hemoglobin subunit alpha P60529 1-141 peptide-Tyr42+Phe-peptide N MS Thr Lys Thr Tyr Phe Pro His Phe Williamson et al., 2004 24613
hemoglobin subunit alpha P60529 1-141 peptide-Thr68+Ala-peptide N MS Ala Leu Thr Thr Ala Val Ala His Williamson et al., 2004 24614
hemoglobin subunit alpha P60529 1-141 peptide-Asp74+Asp-peptide N MS Ala His Leu Asp Asp Leu Pro Gly Williamson et al., 2004 24615
hemoglobin subunit alpha P60529 1-141 peptide-Ala79+Leu-peptide N MS Leu Pro Gly Ala Leu Ser Ala Leu Williamson et al., 2004 24616
hemoglobin subunit alpha P60529 1-141 peptide-Ser81+Ala-peptide N MS Gly Ala Leu Ser Ala Leu Ser Asp Williamson et al., 2004 24617
hemoglobin subunit alpha P60529 1-141 peptide-Pro95+Val-peptide N MS Arg Val Asp Pro Val Asn Phe Lys Williamson et al., 2004 24618
hemoglobin subunit alpha P60529 1-141 peptide-Leu100+Leu-peptide N MS Asn Phe Lys Leu Leu Ser His Cys Williamson et al., 2004 24619
hemoglobin subunit alpha P60529 1-141 peptide-Cys104+Leu-peptide N MS Leu Ser His Cys Leu Leu Val Thr Williamson et al., 2004 24620
hemoglobin subunit alpha P60529 1-141 peptide-Leu105+Leu-peptide N MS Ser His Cys Leu Leu Val Thr Leu Williamson et al., 2004 24621
hemoglobin subunit alpha P60529 1-141 peptide-His112+His-peptide N MS Leu Ala Cys His His Pro Thr Glu Williamson et al., 2004 24622
hemoglobin subunit alpha P60529 1-141 peptide-Phe117+Thr-peptide N MS Pro Thr Glu Phe Thr Pro Ala Val Williamson et al., 2004 24623
hemoglobin subunit alpha P60529 1-141 peptide-Ala123+Ser-peptide N MS Ala Val His Ala Ser Leu Asp Lys Williamson et al., 2004 24624
hemoglobin subunit alpha P60529 1-141 peptide-Asp126+Lys-peptide N MS Ala Ser Leu Asp Lys Phe Phe Ala Williamson et al., 2004 24625
hemoglobin subunit beta P68871 2-147 peptide-Glu44+Ser-peptide N MS Arg Phe Phe Glu Ser Phe Gly Asp Ranjit et al., 2009 24549
hemoglobin subunit beta P68871 2-147 peptide-Gly57+Asn-peptide N MS Ala Val Met Gly Asn Pro Lys Val Ranjit et al., 2009 24550
hemoglobin subunit beta P68871 2-147 peptide-Ser90+Glu-peptide N MS Ala Thr Leu Ser Glu Leu His Cys Ranjit et al., 2009 24551
hemoglobin subunit beta P68871 2-147 peptide-Leu97+His-peptide N MS Cys Asp Lys Leu His Val Asp Pro Ranjit et al., 2009 24552
hemoglobin subunit beta P68871 2-147 peptide-Phe104+Arg-peptide N MS Pro Glu Asn Phe Arg Leu Leu Gly Ranjit et al., 2009 24553
hemoglobin subunit beta P68871 2-147 peptide-Leu106+Leu-peptide N MS Asn Phe Arg Leu Leu Gly Asn Val Ranjit et al., 2009 24554
hemoglobin subunit beta P68871 2-147 peptide-Gly120+Lys-peptide N MS His His Phe Gly Lys Glu Phe Thr Ranjit et al., 2009 24555
hemoglobin subunit beta P68871 2-147 peptide-Gln132+Lys-peptide N MS Ala Ala Tyr Gln Lys Val Val Ala Ranjit et al., 2009 24556
hemoglobin subunit beta P68871 2-147 peptide-Ala141+Leu-peptide N MS Val Ala Asn Ala Leu Ala His Lys Ranjit et al., 2009 24557
hemoglobin subunit beta P60524 1-146 peptide-Trp15+Gly-peptide N MS Ser Gly Leu Trp Gly Lys Val Asn Williamson et al., 2004 24627
hemoglobin subunit beta P60524 1-146 peptide-Gly29+Arg-peptide N MS Glu Ala Leu Gly Arg Leu Leu Ile Williamson et al., 2004 24628
hemoglobin subunit beta P60524 1-146 peptide-Arg30+Leu-peptide N MS Ala Leu Gly Arg Leu Leu Ile Val Williamson et al., 2004 24629
hemoglobin subunit beta P60524 1-146 peptide-Val34+Tyr-peptide N MS Leu Leu Ile Val Tyr Pro Trp Thr Williamson et al., 2004 24630
hemoglobin subunit beta P60524 1-146 peptide-Tyr35+Pro-peptide N MS Leu Ile Val Tyr Pro Trp Thr Gln Williamson et al., 2004 24631
hemoglobin subunit beta P60524 1-146 peptide-Pro36+Trp-peptide N MS Ile Val Tyr Pro Trp Thr Gln Arg Williamson et al., 2004 24632
hemoglobin subunit beta P60524 1-146 peptide-Thr38+Gln-peptide N MS Tyr Pro Trp Thr Gln Arg Phe Phe Williamson et al., 2004 24633
hemoglobin subunit beta P60524 1-146 peptide-Gln39+Arg-peptide N MS Pro Trp Thr Gln Arg Phe Phe Asp Williamson et al., 2004 24634
hemoglobin subunit beta P60524 1-146 peptide-Ser56+Asn-peptide N MS Ala Val Met Ser Asn Ala Lys Val Williamson et al., 2004 24635
hemoglobin subunit beta P60524 1-146 peptide-Asn69+Ser-peptide N MS Lys Val Leu Asn Ser Phe Ser Asp Williamson et al., 2004 24636
hemoglobin subunit beta P60524 1-146 peptide-Asp99+Pro-peptide N MS Leu His Val Asp Pro Glu Asn Phe Williamson et al., 2004 24639
hemoglobin subunit beta P60524 1-146 peptide-Val111+Cys-peptide N MS Asn Val Leu Val Cys Val Leu Ala Williamson et al., 2004 24640
hemoglobin subunit beta P60524 1-146 peptide-Asn139+Ala-peptide N MS Gly Val Ala Asn Ala Leu Ala His Williamson et al., 2004 24641
hemoglobin subunit beta P60524 1-146 peptide-Ser12+Gly-peptide N MS Ser Leu Val Ser Gly Leu Trp Gly Williamson et al., 2004
hemoglobin subunit beta P60524 1-146 peptide-Leu96+His-peptide N MS Cys Asp Lys Leu His Val Asp Pro Williamson et al., 2004

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