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Literature for peptidase C01.101: cathepsin B-like peptidase, nematode

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Karunakaran,A.C., Bakshi,M., Rajendrakumar,A.M., Wilson-Welder,J.H., Aroian,R.V., Schwarz,E.M., Homan,E.J., Ostroff,G.R., Beshah,E., Miramontes,E., Papadopoulos,M.D., Bowdridge,S.A., Zarlenga,D.S., Zhu,X. and Tuo,W.<br>Catalytically Active Recombinant Cysteine Proteases of Haemonchus contortus: Their Ability to Degrade Host Blood Proteins and Modulate Coagulation<br>Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2019
  2. Noon,J.B., Schwarz,E.M., Ostroff,G.R. and Aroian,R.V.<br>A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection<br>PLoS Negl Trop Dis (2019) 13, e0007345-e0007345. PubMed  Europe PubMed DOI
    3. 2013
  3. Prasad,A., Yadav,N., Allaie,I.M., Sankar,M. and Nasir,A.<br>Intraspecific and gender variation in hmcp4 gene of cysteine proteinase in Haemonchus contortus<br>Indian J Anim Sci (2013) 83, 1271-1274.
    4. 2012
  4. Caffrey,C.R., Britton,C. and McKerrow,J.H.<br>Helminth cysteine proteases<br>[ISSN:978-0-12-407743-0] (2012) 3, 1949-1957. DOI
  5. Cheng,M., Yang,X., Li,Z., He,H., Qu,Z., He,A., Wu,Z. and Zhan,X.<br>Cloning and characterization of a novel cathepsin B-like cysteine proteinase from Angiostrongylus cantonensis<br>Parasitol Res (2012) 110, 2413-2422. PubMed  Europe PubMed DOI
    6. 2011
  6. Han,Y.P., Li,Z.Y., Li,B.C., Sun,X., Zhu,C.C., Ling,X.T., Zheng,H.Q., Wu,Z.D. and Lv,Z.Y.<br>Molecular cloning and characterization of a cathepsin B from Angiostrongylus cantonensis<br>Parasitol Res (2011) 109, 369-378. PubMed  Europe PubMed DOI
  7. Yang,Y., Qin,W., Wei,H., Ying,J. and Zhen,J.<br>Characterization of cathepsin B proteinase (AcCP-2) in eggs and larvae stages of hookworm Ancylostoma caninum<br>Exp Parasitol (2011) 129, 215-220. PubMed  Europe PubMed DOI
    8. 2009
  8. De Vries,E., Bakker,N., Krijgsveld,J., Knox,D.P., Heck,A.J. and Yatsuda,A.P.<br>An AC-5 cathepsin B-like protease purified from Haemonchus contortus excretory secretory products shows protective antigen potential for lambs<br>Vet Res (2009) 40, 41-41. PubMed  Europe PubMed DOI  PMC  EPMC
  9. Ranjit,N., Zhan,B., Hamilton,B., Stenzel,D., Lowther,J., Pearson,M., Gorman,J., Hotez,P. and Loukas,A.<br>Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus<br>J Infect Dis (2009) 199, 904-912. PubMed  Europe PubMed DOI
    10. 2008
  10. Ranjit,N., Zhan,B., Stenzel,D.J., Mulvenna,J., Fujiwara,R., Hotez,P.J. and Loukas,A.<br>A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus<br>Mol Biochem Parasitol (2008) 160, 90-99. PubMed  Europe PubMed DOI
    11. 2006
  11. Baska,P., Wisniewski,M., Mieszczanek,J. and Wedrychowicz,H.<br>Computational analysis of Ancylostoma ceylanicum cysteine proteinase<br>Wiad Parazytol (2006) 52, 277-281. PubMed  Europe PubMed
  12. Yatsuda,A.P., Bakker,N., Krijgsveld,J., Knox,D.P., Heck,A.J. and De Vries,E.<br>Identification of secreted cysteine proteases from the parasitic nematode Haemonchus contortus detected by biotinylated inhibitors<br>Infect Immun (2006) 74, 1989-1993. PubMed  Europe PubMed DOI  PMC  EPMC
    13. 2004
  13. Caffrey,C.R. and McKerrow,J.H.<br>Helminth cysteine proteases<br>[ISSN:0-12-079610-4] (2004) 2, 1183-1186.  V
  14. Jasmer,D.P., Mitreva,M.D. and McCarter,J.P.<br>mRNA sequences for Haemonchus contortus intestinal cathepsin B-like cysteine proteases display an extreme in abundance and diversity compared with other adult mammalian parasitic nematodes<br>Mol Biochem Parasitol (2004) 137, 297-305. PubMed  Europe PubMed DOI
  15. [YEAR:22-10-2004]Redmond,D.L. and Knox,D.P.<br>Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortus<br>Vaccine (22-10-2004) 22, 4252-4261. PubMed  Europe PubMed DOI
  16. Ruiz,A., Molina,J.M., Gonzalez,J.F., Conde,M.M., Martin,S. and Hernandez,Y.I.<br>Immunoprotection in goats against Haemonchus contortus after immunization with cysteine protease enriched protein fractions<br>Vet Res (2004) 35, 565-572. PubMed  Europe PubMed DOI
    17. 2001
  17. [YEAR:3-9-2001]Jasmer,D.P., Roth,J. and Myler,P.J.<br>Cathepsin B-like cysteine proteases and Caenorhabditis elegans homologues dominate gene products expressed in adult Haemonchus contortus intestine<br>Mol Biochem Parasitol (3-9-2001) 116, 159-169. PubMed  Europe PubMed DOI
  18. [YEAR:26-1-2001]Shompole,S. and Jasmer,D.P.<br>Cathepsin B-like cysteine proteases confer intestinal cysteine protease activity in Haemonchus contortus<br>J Biol Chem (26-1-2001) 276, 2928-2934. PubMed  Europe PubMed DOI  I
    19. 2000
  19. Mieszczanek,J., Kofta,W. and Wedrychowicz,H.<br>Molecular cloning of a cysteine proteinase cDNA from adult Ancylostoma ceylanicum by the method of rapid amplification of cDNA ends using polymerase chain reaction<br>Parasitol Res (2000) 86, 993-998. PubMed  Europe PubMed
    20. 1999
  20. [YEAR:20-8-1999]Rehman,A. and Jasmer,D.P.<br>Defined characteristics of cathepsin B-like proteins from nematodes: inferred functional diversity and phylogenetic relationships<br>Mol Biochem Parasitol (20-8-1999) 102, 297-310. PubMed  Europe PubMed DOI
  21. Skuce,P.J., Redmond,D.L., Liddell,S., Stewart,E.M., Newlands,G.F., Smith,W.D. and Knox,D.P.<br>Molecular cloning and characterization of gut-derived cysteine proteinases associated with a host protective extract from Haemonchus contortus<br>Parasitology (1999) 119, 405-412. PubMed  Europe PubMed DOI
  22. Tort,J., Brindley,P.J., Knox,D., Wolfe,K.H. and Dalton,J.P.<br>Proteinases and associated genes of parasitic helminths<br>Adv Parasitol (1999) 43, 161-266. PubMed  Europe PubMed  V
    23. 1997
  23. Rhoads,M.L. and Fetterer,R.H.<br>Extracellular matrix: a tool for defining the extracorporeal function of parasite proteases<br>Parasitol Today (1997) 13, 119-122. PubMed  Europe PubMed
    24. 1996
  24. Brinkworth,R.I., Brindley,P.J. and Harrop,S.A.<br>Structural analysis of the catalytic site of AcCP-1, a cysteine proteinase secreted by the hookworm Ancylostoma caninum<br>Biochim Biophys Acta (1996) 1298, 4-8. PubMed  Europe PubMed DOI
    25. 1995
  25. Harrop,S.A., Sawangjaroen,N., Prociv,P. and Brindley,P.J.<br>Characterization and localization of cathepsin B proteinases expressed by adult Ancylostoma caninum hookworms<br>Mol Biochem Parasitol (1995) 71, 163-171. PubMed  Europe PubMed DOI
  26. Rhoads,M.L. and Fetterer,R.H.<br>Developmentally regulated secretion of cathepsin L-like cysteine proteases by Haemonchus contortus<br>J Parasitol (1995) 81, 505-512. PubMed  Europe PubMed DOI
    27. 1992
  27. Pratt,D., Boisvenue,R.J. and Cox,G.N.<br>Isolation of putative cysteine protease genes of Ostertagia ostertagi<br>Mol Biochem Parasitol (1992) 56, 39-48. PubMed  Europe PubMed DOI
  28. Pratt,D., Armes,L.G., Hageman,R., Reynolds,V., Boisvenue,R.J. and Cox,G.N.<br>Cloning and sequence comparisons of four distinct cysteine proteases expressed by Haemonchus contortus adult worms<br>Mol Biochem Parasitol (1992) 51, 209-218. PubMed  Europe PubMed DOI

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