Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P60529

,

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
2	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
5	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
11	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
12	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
14	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
18	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
20	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
23	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
27	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
29	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
30	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
31	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
33	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
34	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
36	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
40	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
42	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
43	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
46	necepsin-1	1-141	N	normal turnover	MS	Williamson et al., 2004
48	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
51	necepsin-1	1-141	N	normal turnover	MS	Williamson et al., 2004
55	necepsin-1	1-141	N		NT	Williamson et al., 2003
56	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
58	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
64	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
68	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
69	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
70	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
74	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
75	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
76	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
78	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
79	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
80	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
81	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
82	necepsin-1	1-141	N	normal turnover	MS	Williamson et al., 2004
83	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
86	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
88	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
91	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
92	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
93	necepsin-1	1-141	N		NT	Williamson et al., 2003
94	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
95	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
96	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
98	necepsin-1	1-141	N	normal turnover	MS	Williamson et al., 2004
99	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
100	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
104	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
105	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
107	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
111	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
112	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
114	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
117	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
119	MEP peptidase (nematode)	1-141	N			Williamson et al., 2004
121	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
122	necepsin-1	1-141	N	normal turnover	MS	Williamson et al., 2004
123	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
126	cathepsin B-like peptidase, nematode	1-141	N			Williamson et al., 2004
128	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
129	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
131	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004
133	necepsin-1	1-141	N		NT	Williamson et al., 2003
136	necepsin-1	1-141	N	normal turnover		Williamson et al., 2004