$VAR1 = undef;

Summary for peptidase C01.101: cathepsin B-like peptidase, nematode

Names
MEROPS Name	cathepsin B-like peptidase, nematode
Other names	Ac-CP-1 (Ancylostoma caninum), Ac-CP-2 (Ancylostoma caninum), acey-1 (Ancylostoma ceylanicum), AC-2 (Haemonchus contortus), AC-3 (Haemonchus contortus), AC-4 (Haemonchus contortus), AC-5 (Haemonchus contortus)

Domain architecture

MEROPS Classification
Classification	Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.101
Holotype	cathepsin B-like peptidase, nematode (Haemonchus contortus), Uniprot accession P19092 (peptidase unit: 78-338), MERNUM MER0000701
History	Identifier created: MEROPS 5.61 (29 October 2001)

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (45 cleavages)
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/--/-/-/- (based on 47 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	2	1	2	4	3	1	3	4
Pro	3	2	0	2	4	5	3	2
Ala	11	5	3	5	5	2	5	3
Val	1	10	3	2	3	6	3	7
Leu	6	6	10	7	7	10	3	2
Ile	1	2	2	0	0	0	1	1
Met	0	0	2	0	0	0	2	0
Phe	2	3	2	4	1	4	5	5
Tyr	1	0	2	2	1	0	0	0
Trp	0	1	1	1	1	4	2	0
Ser	3	2	2	5	3	2	2	0
Thr	1	2	3	2	2	3	5	3
Cys	2	0	2	1	1	0	0	2
Asn	6	0	2	2	2	1	2	1
Gln	0	0	0	2	1	0	1	1
Asp	1	2	1	3	1	2	4	4
Glu	1	3	1	1	3	2	0	1
Lys	1	4	6	0	3	1	2	8
Arg	2	0	1	3	3	3	0	1
His	3	4	2	1	3	1	4	2