Substrates for peptidase M01.026: aminopeptidase Q

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ala-Mca Ala+Mca S - - - Ala MCA - - - Maruyama et al., 2007
angiotensin-3 P01019 35-41 Arg+Val-Tyr-Ile-His-Pro-Phe N - - - Arg Val Tyr Ile His Maruyama et al., 2007
Arg-Mca Arg+Mca S - - - Arg MCA - - - Maruyama et al., 2007
dynorphin A(1-8) P01213 207-214 Tyr+Gly-Gly-Phe-Leu-Arg-Arg-Ile N - - - Tyr Gly Gly Phe Leu Maruyama et al., 2007 20308
dynorphin A(2-8) P01213 208-214 Gly+Gly-Phe-Leu-Arg-Arg-Ile N - - - Gly Gly Phe Leu Arg Maruyama et al., 2007
dynorphin A(3-8) P01213 209-214 Gly+Phe-Leu-Arg-Arg-Ile N - - - Gly Phe Leu Arg Arg Maruyama et al., 2007
endokinin C Q86UU9 82-95 Lys+Lys-Ala-Tyr-Gln-Leu-Glu-His-Thr-Phe-Gln-Gly-Leu-Leu N - - - Lys Lys Ala Tyr Gln Maruyama et al., 2007 20307
Gln-Mca Gln+Mca S - - - Gln MCA - - - Maruyama et al., 2007
kisspeptin-10 Q15726 112-121 Tyr+Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe N - - - Tyr Asn Trp Asn Ser Maruyama et al., 2007 20306
Leu-Mca Leu+Mca S - - - Leu MCA - - - Maruyama et al., 2007
Lys-Mca Lys+Mca S - - - Lys MCA - - - Maruyama et al., 2007
Met-Mca Met+Mca S - - - Met MCA - - - Maruyama et al., 2007
Phe-Mca Phe+Mca S - - - Phe MCA - - - Maruyama et al., 2007
SBzl-Cys-Mca SBzl-Cys+Mca S - - SBz Cys MCA - - - Maruyama et al., 2007
[des-Lys]endokinin C Q86UU9 83-95 Lys+Ala-Tyr-Gln-Leu-Glu-His-Thr-Phe-Gln-Gly-Leu-Leu N - - - Lys Ala Tyr Gln Leu Maruyama et al., 2007
[des-Tyr]kisspeptin-10 Q15726 113-121 Asn+Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe N - - - Asn Trp Asn Ser Phe Maruyama et al., 2007
[Lys]-bradykinin (kallidin) P01042 380-389 Lys+Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg N - - - Lys Arg Pro Pro Gly Maruyama et al., 2007