$VAR1 = undef;

Summary for peptidase M01.026: aminopeptidase Q

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Nameaminopeptidase Q
Other nameslaeverin, Mername-AA105 peptidase, Mername-AA009 protein, Mername-AA120 peptidase, Taqpep
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M1 >> Subfamily (none) >> M01.026
Holotypeaminopeptidase Q (Homo sapiens), Uniprot accession Q6Q4G3 (peptidase unit: 324-545), MERNUM MER0052595
History Identifier created: MEROPS 5.61 (29 October 2001)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (3 cleavages)
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR11533:SF31
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 17 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 2 2 1 0 1
Pro 0 0 0 0 0 1 1 0
Ala 0 0 0 1 1 1 0 0
Val 0 0 0 0 1 0 0 0
Leu 0 0 0 1 0 1 1 2
Ile 0 0 0 0 0 0 1 0
Met 0 0 0 1 0 0 0 0
Phe 0 0 0 1 1 1 1 1
Tyr 0 0 0 2 0 2 1 0
Trp 0 0 0 0 1 1 0 0
Ser 0 0 0 0 0 0 1 1
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 1 0 0 0 0
Asn 0 0 0 1 1 1 1 0
Gln 0 0 0 1 0 0 1 1
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 4 1 0 0 0
Arg 0 0 0 2 1 0 1 2
His 0 0 0 0 0 0 0 1
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
5q23.1 ENSG00000172901 206338 610046