Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q15726

,

Click here to display alignment and conservation of cleavage sites of this sequence with close homologues. This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	unknown peptidase	1-138	P		NT	<%Agarwal et al., 2012[]%>
112	aminopeptidase Q	112-121	N			Maruyama et al., 2007
113	aminopeptidase Q	113-121	N			Maruyama et al., 2007
118	matrix metallopeptidase-2	20-145	P	normal turnover		Takino et al., 2003
118	matrix metallopeptidase-9	20-145	P	normal turnover		Takino et al., 2003
118	membrane-type matrix metallopeptidase-1	20-145	P			Takino et al., 2003
118	membrane-type matrix metallopeptidase-3	20-145	P			Takino et al., 2003
118	membrane-type matrix metallopeptidase-5	20-145	P			Takino et al., 2003