Count of substrate cleavages for peptidases

Aspartic, Cysteine, Glutamic, Metallo, Serine, Threonine, Unknown, Compound Peptidase,

ASPARTIC PEPTIDASE
MEROPS IDPeptidaseTotal substratesPhysiological substratesNon-physiological substrates
A01.001 pepsin A417 21 396
A01.002 pepsin B25 1 24
A01.003 gastricsin50 6 44
A01.004 BACE1 g.p. (Homo sapiens)24 16 8
A01.006 chymosin20 11 9
A01.007 renin10 1 9
A01.008 renin-23 1 2
A01.009 cathepsin D897 842 55
A01.010 cathepsin E1596 1552 44
A01.011 penicillopepsin17 0 17
A01.012 rhizopuspepsin249 0 249
A01.013 mucorpepsin9 1 8
A01.014 candidapepsin SAP126 1 25
A01.015 barrierpepsin1 1 0
A01.016 aspergillopepsin I157 1 156
A01.017 endothiapepsin11 0 11
A01.018 saccharopepsin14 3 11
A01.019 polyporopepsin11 0 11
A01.020 phytepsin62 7 55
A01.021 plasmepsin (Plasmodium sp.)5 0 5
A01.022 plasmepsin-113 7 6
A01.023 plasmepsin-215 4 11
A01.026 peptidase F0 0 0
A01.027 trichodermapepsin1 0 1
A01.028 embryonic pepsin (Gallus gallus)0 0 0
A01.030 yapsin-145 5 40
A01.031 yapsin-216 0 16
A01.035 yapsin-39 4 5
A01.036 axp peptidase (Yarrowia lipolytica)3 2 1
A01.037 canditropsin9 2 7
A01.038 candiparapsin5 0 5
A01.040 nepenthesin19 0 19
A01.041 BACE2 g.p. (Homo sapiens)33 5 28
A01.042 syncephapepsin18 0 18
A01.043 histoaspartic peptidase (Plasmodium falciparum)4 0 4
A01.044 podosporapepsin0 0 0
A01.045 nothepsin1 0 1
A01.046 napsin A7 3 4
A01.050 CND41 peptidase0 0 0
A01.051 pepsin F3 2 1
A01.052 Mername-AA045 peptidase0 0 0
A01.053 necepsin-1133 0 133
A01.054 tick heme-binding aspartic proteinase (Rhipicephalus microplus)2 0 2
A01.055 Mername-AA047 peptidase1 0 1
A01.056 Yps1 protein (Schizosaccharomyces pombe)3 0 3
A01.057 Mername-AA034 peptidase0 0 0
A01.058 eimepsin0 0 0
A01.059 plasmepsin-48 2 6
A01.060 candidapepsin SAP222 1 21
A01.061 candidapepsin SAP321 1 20
A01.062 candidapepsin SAP40 0 0
A01.063 candidapepsin SAP50 0 0
A01.064 candidapepsin SAP622 0 22
A01.065 candidapepsin SAP70 0 0
A01.066 candidapepsin SAP80 0 0
A01.067 candidapepsin SAP917 14 3
A01.068 necepsin-245 0 45
A01.069 CDR1 peptidase (Arabidopsis-type)2 0 2
A01.070 pepsin A44 4 0
A01.071 pepsin A5 (Homo sapiens)10 3 7
A01.073 nucellin1 1 0
A01.074 PCS1 peptidase0 0 0
A01.075 plasmepsin-5 (Plasmodium sp.)7 1 6
A01.076 Sapp2p peptidase (Candida parapsilosis)7 1 6
A01.077 CtsD peptidase (Aspergillus-type)0 0 0
A01.078 CnAP1 peptidase0 0 0
A01.079 PepAa peptidase0 0 0
A01.080 PepAb peptidase0 0 0
A01.081 PepAc peptidase0 0 0
A01.082 SA76 peptidase (Trichoderma sp.)0 0 0
A01.083 hCG1733572 (Homo sapiens)-type putative peptidase0 0 0
A01.084 yolk cathepsin (Boophilus sp.)17 0 17
A01.085 candidapepsin SAP1016 14 2
A01.086 S5 peptidase (Oryza sativa)0 0 0
A01.087 toxomepsin 10 0 0
A01.088 pepsin (fish)2 0 2
A01.089 pregnancy-associated glycoprotein 21 0 1
A01.092 CAD2 peptidase (Musca domestica)0 0 0
A01.093 CAD3 peptidase (Musca domestica)2 1 1
A01.094 pregnancy-associated glycoprotein 121 0 1
A01.095 shewasin A (Shewanella amazonensis)5 0 5
A01.096 chlapsin1 0 1
A01.097 GPI-anchored aspartic peptidase (Saccharomyces-type)1 0 1
A01.098 ASP5 g.p. (Toxoplasma gondii)1 0 1
A01.A01 CG31926 g.p. (Drosophila melanogaster)0 0 0
A01.A02 At1g62290 (Arabidopsis thaliana)0 0 0
A01.A03 At4g04460 (Arabidopsis thaliana)0 0 0
A01.A04 CG17283-RA g.p. (Drosophila melanogaster)0 0 0
A01.A05 At1g01300 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A06 At1g25510 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A07 At1g79720 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A08 At2g42980 (Arabidopsis thaliana)0 0 0
A01.A09 ASPG1 peptidase0 0 0
A01.A10 At3g20015 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A11 At3g25700 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A12 At3g59080 (Arabidopsis thaliana)0 0 0
A01.A13 At3g61820 (Arabidopsis thaliana)0 0 0
A01.A14 At5g10760 (Arabidopsis thaliana)0 0 0
A01.A15 At5g10770 (Arabidopsis thaliana)0 0 0
A01.A16 At1g31450 (Arabidopsis thaliana)0 0 0
A01.A17 At1g64830 (Arabidopsis thaliana)0 0 0
A01.A18 At2g28010 (Arabidopsis thaliana)0 0 0
A01.A19 At2g28030 (Arabidopsis thaliana)0 0 0
A01.A20 At2g28040 (Arabidopsis thaliana)0 0 0
A01.A21 At2g28220 (Arabidopsis thaliana)0 0 0
A01.A22 At2g35615 (Arabidopsis thaliana)0 0 0
A01.A23 At3g02740 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A24 At1g44130 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A25 At1g49050 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A26 At1g77480 (Arabidopsis thaliana)0 0 0
A01.A27 At4g33490 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A28 At1g66180 (Arabidopsis thaliana)0 0 0
A01.A29 At2g39710 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A30 At3g12700 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A31 At5g37540 (Arabidopsis thaliana)0 0 0
A01.A32 At1g69100 (Arabidopsis thaliana)0 0 0
A01.A33 At4g22050 (Arabidopsis thaliana)0 0 0
A01.A34 At1g05840 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A35 At1g08210 (Arabidopsis thaliana)0 0 0
A01.A36 At1g09750 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A37 A39 g.p. (Arabidopsis thaliana)0 0 0
A01.A38 At2g17760 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A39 At2g23945 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A40 At2g36670 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A41 At3g42550 (Arabidopsis thaliana)0 0 0
A01.A42 At3g50050 (Arabidopsis thaliana)0 0 0
A01.A43 At3g51330 (Arabidopsis thaliana)0 0 0
A01.A44 At3g51340 (Arabidopsis thaliana)0 0 0
A01.A45 At3g51350 (Arabidopsis thaliana)0 0 0
A01.A46 At3g51360 (Arabidopsis thaliana)0 0 0
A01.A47 At3g52500 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A48 At3g54400 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A49 At4g12920 (Arabidopsis thaliana)0 0 0
A01.A50 At4g16560 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A51 At4g30030 (Arabidopsis thaliana)0 0 0
A01.A52 At4g30040 (Arabidopsis thaliana)0 0 0
A01.A53 At4g35880 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A54 At5g07030 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A55 At5g10080 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A56 At5g22850 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A57 At5g24820-type peptidase0 0 0
A01.A58 A36 g.p. (Arabidopsis thaliana)0 0 0
A01.A59 At5g43100 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A60 At5g45120 (Arabidopsis thaliana)-type peptidase0 0 0
A01.A62 yapsin-6 (Saccharomyces cerevisiae)0 0 0
A01.A63 CG13374 g.p. (Drosophila melanogaster)0 0 0
A01.A64 CG10104 g.p.(Drosophila melanogaster)0 0 0
A01.A65 CG5863 g.p. (Drosophila melanogaster)0 0 0
A01.A66 CG5860 g.p. (Drosophila melanogaster)0 0 0
A01.A67 CG31928 g.p. (Drosophila melanogaster)0 0 0
A01.A68 CG10872 g.p. (Drosophila melanogaster)0 0 0
A01.A69 asp-3 g.p. (Caenorhabditis elegans)0 0 0
A01.A70 K10C2.3 protein (Caenorhabditis elegans)0 0 0
A01.A71 asp-6 g.p. (Caenorhabditis elegans)0 0 0
A01.A72 F59D6.3 protein (Caenorhabditis elegans)0 0 0
A01.A73 Y39B6B.h protein (Caenorhabditis elegans)0 0 0
A01.A74 F21F8.4 protein (Caenorhabditis elegans)0 0 0
A01.A75 C11D2.2 g.p. (Caenorhabditis elegans)0 0 0
A01.A76 C15C8.3 g.p. (Caenorhabditis elegans)0 0 0
A01.A77 F59D6.2 g.p. (Caenorhabditis elegans)0 0 0
A01.A78 CG17134 g.p. (Drosophila melanogaster)0 0 0
A01.A79 CG6508 g.p. (Drosophila melanogaster)0 0 0
A01.A81 CG10872 g.p. (Drosophila melanogaster)0 0 0
A01.A82 Ceasp1 protein (Caenorhabditis elegans)0 0 0
A01.A83 F28A12.4 g.p. (Caenorhabditis elegans)0 0 0
A01.A84 asp-2 g.p. (Caenorhabditis elegans)0 0 0
A01.A85 Y39B6A.23 g.p. (Caenorhabditis elegans)0 0 0
A01.A86 Y39B6A.24 g.p. (Caenorhabditis elegans)0 0 0
A01.A87 ZK384.3 g.p. domain 1 (Caenorhabditis elegans)0 0 0
A01.A88 DDB_0205773 (Dictyostelium discoideum)0 0 0
A01.A89 DDB_G0279411 (Dictyostelium discoideum)0 0 0
A01.A90 DDB_G0277581 (Dictyostelium discoideum)0 0 0
A01.A91 Sxa1 peptidase (Schizosaccharomyces pombe)0 0 0
A01.A92 DDB_G0270722 g.p. (Dictyostelium discoideum)0 0 0
A01.A93 plasmepsin-100 0 0
A01.A94 SCRG_02223 g.p. (Saccharomyces cerevisiae)0 0 0
A01.A95 plasmepsin-90 0 0
A01.A96 hCG39993 g.p. (Homo sapiens)0 0 0
A02.001 HIV-1 retropepsin1046 15 1031
A02.002 HIV-2 retropepsin30 9 21
A02.003 simian immunodeficiency virus retropepsin0 0 0
A02.004 equine infectious anaemia virus retropepsin13 0 13
A02.005 bovine immunodeficiency virus retropepsin11 11 0
A02.006 Visna lentivirus-type retropepsin0 0 0
A02.007 feline immunodeficiency virus retropepsin28 11 17
A02.008 murine leukemia virus-type retropepsin20 6 14
A02.009 Mason-Pfizer leukemia virus retropepsin18 4 14
A02.010 mouse mammary tumor virus retropepsin13 3 10
A02.011 human endogenous retrovirus K retropepsin8 5 3
A02.012 retropepsin (human T-cell leukemia virus)15 8 7
A02.013 bovine leukemia virus retropepsin20 6 14
A02.015 Rous sarcoma virus retropepsin18 2 16
A02.016 intracisternal A-particle retropepsin7 4 3
A02.018 simian T-cell lymphotropic virus retropepsin0 0 0
A02.019 multiple-sclerosis-associated retrovirus retropepsin0 0 0
A02.020 porcine endogenous retrovirus peptidase6 2 4
A02.021 Gypsy transposon peptidase0 0 0
A02.022 Ty3 transposon peptidase5 5 0
A02.024 rabbit endogenous retrovirus endopeptidase1 1 0
A02.051 retrotransposon peptidase (Schizosaccharomyces pombe)0 0 0
A02.052 retrotransposon 17.6 peptidase0 0 0
A02.053 S71-related human endogenous retropepsin0 0 0
A02.054 Osvaldo retrotransposon peptidase0 0 0
A02.055 RTVL-H-type putative peptidase0 0 0
A02.056 human endogenous retrovirus retropepsin homologue 10 0 0
A02.057 human endogenous retrovirus retropepsin homologue 20 0 0
A02.060 type D-like endogenous retrovirus peptidase (Mus musculus)0 0 0
A02.061 Ulysses retrotransposon retropepsin6 0 6
A02.062 TED retrotransposon peptidase (Trichoplusia ni)0 0 0
A02.063 walleye dermal sarcoma virus retropepsin25 13 12
A03.001 cauliflower mosaic virus-type peptidase1 1 0
A03.002 bacilliform virus peptidase6 6 0
A03.003 banana streak virus peptidase0 0 0
A03.004 Commelina yellow mottle virus peptidase0 0 0
A03.005 cassava vein mosaic virus-type peptidase0 0 0
A03.006 retrotransposon peptidase (Nicotiana-type)0 0 0
A05.001 thermopsin18 1 17
A08.001 signal peptidase II5 1 4
A09.001 spumapepsin11 10 1
A11.001 Copia transposon peptidase9 2 7
A11.002 Tnt1 retrotransposon (plant) peptidase0 0 0
A11.003 Ty1 transposon peptidase3 3 0
A11.004 Evelknievel retrotransposon peptidase0 0 0
A11.005 Melmoth transposon peptidase0 0 0
A11.051 SIRE-1 peptidase0 0 0
A22.001 presenilin 116 16 0
A22.002 presenilin 20 0 0
A22.003 impas 1 peptidase6 6 0
A22.004 signal peptide peptidase-like protein 2B5 5 0
A22.005 impas 2 peptidase0 0 0
A22.006 signal peptide peptidase-like protein 2C0 0 0
A22.007 signal peptide peptidase-like protein 2A5 5 0
A22.008 yeast presenilin fold 10 0 0
A22.009 SEL-12 peptidase (Caenorhabditis-type)0 0 0
A22.010 hop-1 peptidase0 0 0
A22.012 SPE-4 peptidase0 0 0
A22.013 mSPP peptidase (Plasmodium-type)0 0 0
A22.014 Psn peptidase (Drosophila-type)0 0 0
A22.015 intramembrane aspartyl peptidase (Methanoculleus marisnigri JR1)8 0 8
A22.A01 AtPS1 protein (Arabidopsis thaliana)0 0 0
A22.A02 AtPS2 protein (Arabidopsis thaliana)0 0 0
A22.A03 At1g01650 (Arabidopsis thaliana)0 0 0
A22.A04 At1g05820 (Arabidopsis thaliana)0 0 0
A22.A05 At1g63690 (Arabidopsis thaliana)0 0 0
A22.A06 At2g43105 (Arabidopsis thaliana)-type peptidase0 0 0
A22.A07 imp-3 g.p. (Caenorhabditis elegans)0 0 0
A22.A08 imp-1 g.p. (Caenorhabditis elegans)0 0 0
A22.A09 psenA (Dictyostelium discoideum)0 0 0
A22.A10 psenB (Dictyostelium discoideum)0 0 0
A22.A11 SPAC25B8.17 (Schizosaccharomyces pombe)0 0 0
A22.A12 DDB_G0292836 (Dictyostelium discoideum)0 0 0
A22.A13 DDB_G0287521 (Dictyostelium discoideum)0 0 0
A22.A14 At4g33410 g.p. (Arabidopsis thaliana)0 0 0
A22.A15 At2g03120 g.p. (Arabidopsis thaliana)0 0 0
A24.001 type 4 prepilin peptidase 116 16 0
A24.003 type 4 prepilin peptidase 20 0 0
A24.016 FlaK peptidase6 1 5
A24.017 PibD peptidase18 3 15
A24.018 EppA peptidase2 2 0
A24.019 ComC peptidase0 0 0
A24.A01 PppA protein (Escherichia coli)0 0 0
A24.A10 gspO g.p. (Escherichia coli)0 0 0
A25.001 gpr peptidase32 0 32
A26.001 omptin54 16 38
A26.002 OmpP peptidase11 1 10
A26.003 plasminogen activator Pla16 2 14
A26.004 protein E (Salmonella sp.)2 2 0
A26.005 IcsP peptidase (Shigella flexneri)1 1 0
A28.001 DNA-damage inducible protein 10 0 0
A28.002 nuclear receptor-interacting protein 30 0 0
A28.003 DNA-damage inducible protein 20 0 0
A28.004 skin SASPase15 11 4
A28.A01 gene name 1700011N24Rik (Mus musculus)0 0 0
A28.A02 C01G5.6 (Caenorhabditis elegans)0 0 0
A28.A03 At3g13235 (Arabidopsis thaliana)0 0 0
A28.A04 DDB_G0288187 (Dictyostelium discoideum)0 0 0
A28.A05 CG4420 g.p. (Drosophila melanogaster)0 0 0
A28.A06 putative v-snare binding protein (Schizosaccharomyces pombe)0 0 0
A28.A07 PF14_0090 (Plasmodium falciparum)0 0 0
A28.A08 DDB_G0279931 (Dictyostelium discoideum)0 0 0
A28.A09 K02A2.6 (Caenorhabditis elegans)0 0 0
A28.A10 nuclear receptor interacting protein 20 0 0
A31.001 HybD peptidase4 3 1
A31.002 HyaD peptidase0 0 0
A31.003 HycI peptidase1 1 0
A31.004 hoxW peptidase0 0 0
A31.005 hupW peptidase1 1 0
A31.006 FrxA peptidase1 1 0
A31.007 TK2004 peptidase0 0 0
A31.008 TK2066 peptidase0 0 0
A32.001 PerP peptidase (Caulobacter sp.)0 0 0
A32.002 RC1339 g.p. (Rickettsia conorii)800 0 800
A36.001 sporulation factor SpoIIGA4 4 0
A37.001 sso1175 g.p. (Sulfolobus solfataricus)6 0 6
A39.001 TseI g.p. (Aeromonas dhakensis)0 0 0
A9G.001 aspartic peptidase, plasma0 0 0
A9G.008 rhodotorulapepsin7 0 7
A9G.010 pycnoporopepsin8 0 8
A9G.017 acid peptidase (Cladosporium)8 0 8
A9G.018 acid peptidase (Paecilomyces)0 0 0
A9G.019 acrocylindropepsin6 0 6
A9G.020 yapsin A9 0 9