Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P48061

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
21	unknown peptidase	1-93	P		NT	<%Agarwal et al., 2012[]%>
23	dipeptidyl-peptidase IV (eukaryote)	22-93	P			Christopherson et al., 2002
23	dipeptidyl-peptidase 8	22-93	P			Ajami et al., 2008
25	matrix metallopeptidase-2	22-93	P			McQuibban et al., 2001
25	matrix metallopeptidase-9	22-93	P			Van den Steen et al., 2003
26	cathepsin G	22-93	P			delgado et al., 2001
86	cathepsin X	24-87	P		MS	Staudt et al., 2010
87	cathepsin X	24-88	P		MS	Staudt et al., 2010
88	cathepsin X	24-89	P		MS	Staudt et al., 2010
88	carboxypeptidase N	22-93	P			Davis et al., 2005
88	carboxypeptidase M	22-93	P			Marquez-Curtis et al., 2008