Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P14210

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
31	unknown peptidase	1-728	P		NT	<%Agarwal et al., 2012[]%>
134	coagulation factor Xa	32-728	P		NT	Pediaditakis et al., 2002
424	plasma kallikrein	32-728	P			Peek et al., 2002
424	coagulation factor XIa	32-728	P			Peek et al., 2002
480	chymase (Homo sapiens-type)	32-728	P			Andersson et al., 2008
493	chymase (Homo sapiens-type)	32-728	P		MS	Raymond et al., 2006
494	plasma kallikrein	32-728	P			Peek et al., 2002
494	coagulation factor XIa	32-728	P			Peek et al., 2002
494	hepsin	32-728	P			Herter et al., 2005
494	hepatocyte growth factor activator	32-728	P			Kitamura, 2004
494	urokinase-type plasminogen activator	32-728	P		MU	Mars et al., 1993
494	matriptase	32-728	P			Uhland, 2006
494	PCSK4 peptidase	489-498	N		CS	Remacle et al., 2008
494	PCSK6 peptidase	489-498	N		CS	Remacle et al., 2008
494	PCSK5 peptidase	489-498	N		CS	Remacle et al., 2008
494	PCSK7 peptidase	489-498	N		CS	Remacle et al., 2008