Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P10915

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
15	unknown peptidase	1-354	P		NT	<%Agarwal et al., 2012[]%>
28	plasmin	16-354	N		NT	Nguyen et al., 1991
31	matrix metallopeptidase-1	16-354	P	normal turnover		Nguyen et al., 1993
31	matrix metallopeptidase-2	16-354	P			Nguyen et al., 1993
31	matrix metallopeptidase-9	16-354	P	normal turnover		Nguyen et al., 1993
31	matrix metallopeptidase-3	16-354	P	normal turnover		Nguyen et al., 1993
31	matrix metallopeptidase-10 (Homo sapiens-type)	16-354	P	normal turnover		Nguyen et al., 1993
31	chymotrypsin A (cattle-type)	16-354	N		NT	Nguyen et al., 1991
32	elastase-2	16-354	N		NT	Nguyen et al., 1991
33	cathepsin B	16-354	P		NT	Nguyen et al., 1990
33	cathepsin G	16-354	P		NT	Nguyen et al., 1991
34	cathepsin B	16-354	P		NT	Nguyen et al., 1990
39	pepsin A	16-354	N		NT	Nguyen et al., 1991
39	elastase-1	16-354	N		NT	Nguyen et al., 1991
40	cathepsin B	16-354	P		NT	Nguyen et al., 1990
40	matrix metallopeptidase-2	16-354	P			Nguyen et al., 1993
40	matrix metallopeptidase-10 (Homo sapiens-type)	16-354	P	normal turnover		Nguyen et al., 1993
40	matrix metallopeptidase-7	16-354	P	normal turnover		Nguyen et al., 1993
41	pepsin A	16-354	N		NT	Nguyen et al., 1991
41	cathepsin D	16-354	N		NT	Nguyen et al., 1991
41	elastase-1	16-354	N		NT	Nguyen et al., 1991
42	cathepsin L	16-354	P		NT	Nguyen et al., 1990
43	cathepsin L	16-354	P		NT	Nguyen et al., 1990
70	chymotrypsin A (cattle-type)	16-354	N		NT	Nguyen et al., 1991
71	cathepsin L	16-354	P		NT	Nguyen et al., 1990