Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P0C0L4

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	unknown peptidase	1-1744	P		NT	<%Agarwal et al., 2012[]%>
675	unknown peptidase	1-1744	P		NT	<%Agarwal et al., 2012[]%>
679	unknown peptidase	1-1744	P		NT	<%Agarwal et al., 2012[]%>
755	carboxypeptidase N	680-756	P
756	interpain A	680-1446	N		NT	Potempa et al., 2009
756	complement component activated C1s	20-1744	P			Sim & Tsiftsoglou, 2004
756	mannan-binding lectin-associated serine peptidase 1	20-1744	P			Ogata et al., 1995
756	mannan-binding lectin-associated serine peptidase 2	20-1744	P			Matsushita et al., 2000
956	complement factor I	20-1744	P			Sim, 2004
981	interpain A	680-1446	N		NT	Potempa et al., 2009
1336	complement factor I	20-1744	P			Sim, 2004
1446	unknown peptidase	1-1744	P		NT	<%Agarwal et al., 2012[]%>
1453	unknown peptidase	1-1744	P		NT	<%Agarwal et al., 2012[]%>