Substrates for peptidase S01.199: complement factor I

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
complement C3 P01024 23-1663 peptide-Arg1303+Ser-peptide P Leu Pro Ser Arg Ser Ser Lys Ile de Bruijn & Fey, 1985 17336
complement C3 P01024 23-1663 peptide-Arg1320+Ser-peptide P Ser Leu Leu Arg Ser Glu Glu Thr de Bruijn & Fey, 1985 17337
complement C3-1 P98093 1-1640 peptide-Arg1295+Thr-peptide N Phe His Thr Arg Thr Asp Lys Val 17335
complement component C3 P01027 23-1663 peptide-Arg1303+Ser-peptide N Leu Pro Ser Arg Ser Ser Ala Thr 17333
complement component C3 P01027 23-1663 peptide-Arg1320+Ser-peptide N Asn Leu Leu Arg Ser Glu Glu Thr 17334
complement component C4 P0C0L4 20-1744 peptide-Arg950+Thr951-peptide P His Arg Gly Arg Thr Leu Glu Ile Sim, 2004 17339
complement component C4 P0C0L4 20-1744 peptide-Arg1330+Asn1331-peptide P Ser Thr Gly Arg Asn Gly Phe Lys Sim, 2004 17338