Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P09240

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
20	unknown peptidase	1-115	P		NT	<%Agarwal et al., 2012[]%>
45	PCSK2 peptidase	21-115	P		MS	Pan et al., 2006
60	carboxypeptidase A4	46-61	N			Tanco et al., 2010
60	carboxypeptidase A6	46-61	N			Lyons & Fricker, 2010
61	carboxypeptidase A4	46-62	N			Tanco et al., 2010
61	carboxypeptidase A6	46-62	N			Lyons & Fricker, 2010
62	carboxypeptidase A4	46-63	P		MS	Tanco et al., 2010
64	PCSK1 peptidase	21-115	P		NT	Rehfeld, 2006
64	PCSK2 peptidase	21-115	P		MS	Pan et al., 2006
70	PCSK1 peptidase	21-115	P		NT	Rehfeld, 2006
70	PCSK2 peptidase	21-115	P		NT	Rehfeld, 2006
81	PCSK2 peptidase	21-115	P		NT	Rehfeld, 2006
95	aminopeptidase B	95-103	P			Beinfeld et al., 2009
98	tripeptidyl-peptidase I	96-103	P	normal turnover	MS	Warburton & Bernardini, 2002
101	tripeptidyl-peptidase I	99-103	P	normal turnover	MS	Warburton & Bernardini, 2002
106	PCSK2 peptidase	21-115	P		NT	Rehfeld, 2006