Substrates for peptidase S08.027: cell envelope peptidase A (Streptococcus-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
antibacterial peptide LL-37	P49913	134-170	peptide-Lys141+Ser-peptide	P	NT	Phe	Phe	Arg	Lys	Ser	Lys	Glu	Lys	Biswas et al., 2021
C-X-C motif chemokine 2	P10889	1-100	peptide-Gln91+Lys-peptide	P		Lys	Ile	Ile	Gln	Lys	Ile	Leu	Asn	Hidalgo-Grass et al., 2006	21640
cell surface serine endopeptidase CspA	Q3JYS0	36-1571	peptide-Gln143+Asn-peptide	P		Glu	Thr	Pro	Gln	Asn	Ile	Asp	Ser	Bryan & Shelver, 2009
interleukin-8 precursor	P10145	1-99	peptide-Gln86+Arg-peptide	P		Asn	Trp	Val	Gln	Arg	Val	Val	Glu	Hidalgo-Grass et al., 2006	21639