Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P10145

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
20	unknown peptidase	1-102	P	release of a signal peptide	NT	Yoshimura et al., 1989
22	unknown peptidase	1-99	P		NT	<%Agarwal et al., 2012[]%>
26	unknown peptidase	1-99	P		NT	<%Agarwal et al., 2012[]%>
27	cathepsin L	21-99	P	normal turnover		Ohashi et al., 2003
27	gingipain RgpA	23-99	N			Dias et al., 2007
27	matrix metallopeptidase-8	23-99	P			Tester et al., 2007
27	matrix metallopeptidase-13	23-99	P			Tester et al., 2007
27	membrane-type matrix metallopeptidase-1	21-99	P			Tam et al., 2004
28	matrix metallopeptidase-1	23-99	P			Tester et al., 2007
28	matrix metallopeptidase-9	21-99	N			Van den Steen et al., 2003
29	unknown peptidase	1-99	P		NT	<%Agarwal et al., 2012[]%>
30	gingipain K	23-99	P			Dias et al., 2007
33	gingipain RgpA	23-99	N			Dias et al., 2007
38	gingipain K	23-99	P			Dias et al., 2007
42	gingipain K	23-99	P			Dias et al., 2007
86	cell envelope peptidase A (Streptococcus-type)	1-99	P			Hidalgo-Grass et al., 2006