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Substrates for peptidase M13.011: MEP peptidase (nematode)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
hemoglobin subunit alpha P69905 2-142 peptide-Ala20+His-peptide N MS Lys Val Gly Ala His Ala Gly Glu Ranjit et al., 2009 24461
hemoglobin subunit alpha P69905 2-142 peptide-Lys12+Ala-peptide N MS Thr Asn Val Lys Ala Ala Trp Gly Ranjit et al., 2009 24460
hemoglobin subunit alpha P69905 2-142 peptide-His46+Phe-peptide N MS Tyr Phe Pro His Phe Asp Leu Ser Ranjit et al., 2009 24462
hemoglobin subunit alpha P69905 2-142 peptide-Ser50+His-peptide N MS Phe Asp Leu Ser His Gly Ser Ala Ranjit et al., 2009 24463
hemoglobin subunit alpha P69905 2-142 peptide-Lys57+Gly-peptide N MS Ala Gln Val Lys Gly His Gly Lys Ranjit et al., 2009 24464
hemoglobin subunit alpha P69905 2-142 peptide-Ala64+Asp-peptide N MS Lys Lys Val Ala Asp Ala Leu Thr Ranjit et al., 2009 24465
hemoglobin subunit alpha P69905 2-142 peptide-Thr68+Asn-peptide N MS Asp Ala Leu Thr Asn Ala Val Ala Ranjit et al., 2009 24466
hemoglobin subunit alpha P69905 2-142 peptide-Asn69+Ala-peptide N MS Ala Leu Thr Asn Ala Val Ala His Ranjit et al., 2009 24467
hemoglobin subunit alpha P69905 2-142 peptide-Ala72+His-peptide N MS Asn Ala Val Ala His Val Asp Asp Ranjit et al., 2009 24468
hemoglobin subunit alpha P69905 2-142 peptide-Asp75+Asp-peptide N MS Ala His Val Asp Asp Met Pro Asn Ranjit et al., 2009 24469
hemoglobin subunit alpha P69905 2-142 peptide-Leu84+Ser-peptide N MS Leu Ser Ala Leu Ser Asp Leu His Ranjit et al., 2009 24470
hemoglobin subunit alpha P69905 2-142 peptide-Ser85+Asp-peptide N MS Ser Ala Leu Ser Asp Leu His Ala Ranjit et al., 2009 24471
hemoglobin subunit alpha P69905 2-142 peptide-Leu92+Arg-peptide N MS Ala His Lys Leu Arg Val Asp Pro Ranjit et al., 2009 24472
hemoglobin subunit alpha P69905 2-142 peptide-Ala124+Ser-peptide N MS Ala Val His Ala Ser Leu Asp Lys Ranjit et al., 2009 24473
hemoglobin subunit alpha P69905 2-142 peptide-Ser125+Leu-peptide N MS Val His Ala Ser Leu Asp Lys Phe Ranjit et al., 2009 24474
hemoglobin subunit alpha P69905 peptide-Ala20+His-peptide N MS Lys Val Gly Ala His Ala Gly Glu Ranjit et al., 2009 24475
Hemoglobin subunit alpha P69905 peptide-Lys12+Ala-peptide P MS Thr Asn Val Lys Ala Ala Trp Gly Ranjit et al., 2009 24476
Hemoglobin subunit alpha P69905 peptide-His46+Phe-peptide P MS Tyr Phe Pro His Phe Asp Leu Ser Ranjit et al., 2009 24477
Hemoglobin subunit alpha P69905 peptide-Ser50+His-peptide P MS Phe Asp Leu Ser His Gly Ser Ala Ranjit et al., 2009 24478
Hemoglobin subunit alpha P69905 peptide-Lys57+Gly-peptide P MS Ala Gln Val Lys Gly His Gly Lys Ranjit et al., 2009 24479
Hemoglobin subunit alpha P69905 peptide-Ala64+Asp-peptide P MS Lys Lys Val Ala Asp Ala Leu Thr Ranjit et al., 2009 24480
Hemoglobin subunit alpha P69905 peptide-Thr68+Asn-peptide P MS Asp Ala Leu Thr Asn Ala Val Ala Ranjit et al., 2009 24481
Hemoglobin subunit alpha P69905 peptide-Asn69+Ala-peptide P MS Ala Leu Thr Asn Ala Val Ala His Ranjit et al., 2009 24482
Hemoglobin subunit alpha P69905 peptide-Ala72+His-peptide P MS Asn Ala Val Ala His Val Asp Asp Ranjit et al., 2009 24483
Hemoglobin subunit alpha P69905 peptide-Asp75+Asp-peptide P MS Ala His Val Asp Asp Met Pro Asn Ranjit et al., 2009 24484
Hemoglobin subunit alpha P69905 peptide-Leu84+Ser-peptide P MS Leu Ser Ala Leu Ser Asp Leu His Ranjit et al., 2009 24485
Hemoglobin subunit alpha P69905 peptide-Ser85+Asp-peptide P MS Ser Ala Leu Ser Asp Leu His Ala Ranjit et al., 2009 24486
Hemoglobin subunit alpha P69905 peptide-Leu92+Arg-peptide P MS Ala His Lys Leu Arg Val Asp Pro Ranjit et al., 2009 24487
Hemoglobin subunit alpha P69905 peptide-Ala124+Ser-peptide P MS Ala Val His Ala Ser Leu Asp Lys Ranjit et al., 2009 24488
Hemoglobin subunit alpha P69905 peptide-Ser125+Leu-peptide P MS Val His Ala Ser Leu Asp Lys Phe Ranjit et al., 2009 24489
hemoglobin subunit alpha P60529 1-141 peptide-Leu2+Ser-peptide N MS - - Val Leu Ser Pro Ala Asp Williamson et al., 2004 24601
hemoglobin subunit alpha P60529 1-141 peptide-His20+Ala-peptide N MS Ile Gly Gly His Ala Gly Asp Tyr Williamson et al., 2004 24602
hemoglobin subunit alpha P60529 1-141 peptide-Asp64+Ala-peptide N MS Lys Val Ala Asp Ala Leu Thr Thr Williamson et al., 2004 24603
hemoglobin subunit alpha P60529 1-141 peptide-Asp75+Leu-peptide N MS His Leu Asp Asp Leu Pro Gly Ala Williamson et al., 2004 24604
hemoglobin subunit alpha P60529 1-141 peptide-Leu80+Ser-peptide N MS Pro Gly Ala Leu Ser Ala Leu Ser Williamson et al., 2004 24605
hemoglobin subunit alpha P60529 1-141 peptide-Arg92+Val-peptide N MS Tyr Lys Leu Arg Val Asp Pro Val Williamson et al., 2004 24606
hemoglobin subunit alpha P60529 1-141 peptide-Asp94+Pro-peptide N MS Leu Arg Val Asp Pro Val Asn Phe Williamson et al., 2004 24607
hemoglobin subunit alpha P60529 1-141 peptide-Lys99+Leu-peptide N MS Val Asn Phe Lys Leu Leu Ser His Williamson et al., 2004 24608
hemoglobin subunit alpha P60529 1-141 peptide-Cys111+His-peptide N MS Thr Leu Ala Cys His His Pro Thr Williamson et al., 2004 24609
hemoglobin subunit alpha P60529 1-141 peptide-Pro119+Ala-peptide N MS Glu Phe Thr Pro Ala Val His Ala Williamson et al., 2004 24610
hemoglobin subunit alpha P69905 2-142 peptide-Ala54+Gln-peptide N MS His Gly Ser Ala Gln Val Lys Gly Ranjit et al., 2009
hemoglobin subunit beta P68871 2-147 peptide-Asn20+Val-peptide N MS Gly Lys Val Asn Val Asp Glu Val Ranjit et al., 2009 24490
hemoglobin subunit beta P68871 2-147 peptide-Glu27+Ala-peptide N MS Val Gly Gly Glu Ala Leu Gly Arg Ranjit et al., 2009 24491
hemoglobin subunit beta P68871 2-147 peptide-Gly30+Arg-peptide N MS Glu Ala Leu Gly Arg Leu Leu Val Ranjit et al., 2009 24492
hemoglobin subunit beta P68871 2-147 peptide-Lys66+Lys-peptide N MS Ala His Gly Lys Lys Val Leu Gly Ranjit et al., 2009 24493
hemoglobin subunit beta P68871 2-147 peptide-Asp74+Gly-peptide N MS Ala Phe Ser Asp Gly Leu Ala His Ranjit et al., 2009 24494
hemoglobin subunit beta P68871 2-147 peptide-Asp80+Asn-peptide N MS Ala His Leu Asp Asn Leu Lys Gly Ranjit et al., 2009 24495
hemoglobin subunit beta P68871 2-147 peptide-Leu82+Lys-peptide N MS Leu Asp Asn Leu Lys Gly Thr Phe Ranjit et al., 2009 24496
hemoglobin subunit beta P68871 2-147 peptide-Tyr131+Gln-peptide N MS Gln Ala Ala Tyr Gln Lys Val Val Ranjit et al., 2009 24497
hemoglobin subunit beta P60524 1-146 peptide-His2+Leu-peptide N MS - - Val His Leu Thr Ala Glu Williamson et al., 2004 24657
hemoglobin subunit beta P60524 1-146 peptide-Gly13+Leu-peptide N MS Leu Val Ser Gly Leu Trp Gly Lys Williamson et al., 2004 24658
hemoglobin subunit beta P60524 1-146 peptide-Asp47+Leu-peptide N MS Ser Phe Gly Asp Leu Ser Thr Pro Williamson et al., 2004 24659
hemoglobin subunit beta P60524 1-146 peptide-Lys76+Asn-peptide N MS Asp Gly Leu Lys Asn Leu Asp Asn Williamson et al., 2004 24663
hemoglobin subunit beta P60524 1-146 peptide-Asn77+Leu-peptide N MS Gly Leu Lys Asn Leu Asp Asn Leu Williamson et al., 2004 24664
hemoglobin subunit beta P60524 1-146 peptide-Leu105+Leu-peptide N MS Asn Phe Lys Leu Leu Gly Asn Val Williamson et al., 2004 24667
hemoglobin subunit beta P60524 1-146 peptide-Ala128+Ala-peptide N MS Gln Val Gln Ala Ala Tyr Gln Lys Williamson et al., 2004 24668
hemoglobin subunit beta P60524 1-146 peptide-Ala137+Gly-peptide N MS Lys Val Val Ala Gly Val Ala Asn Williamson et al., 2004 24669

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