Structure for peptidase M24.017: methionyl aminopeptidase 1 (eukaryote)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
third cobalt in the active site	1.10 Å	2B3H	2B3H	2B3H	2B3H	2B3H	2B3H	Addlagatta et al., 2005
holo form	1.55 Å	2B3K	2B3K	2B3K	2B3K	2B3K	2B3K	Addlagatta et al., 2005
apo form	1.50 Å	2B3L	2B3L	2B3L	2B3L	2B3L	2B3L	Addlagatta et al., 2005
truncated form (delta 1-89); complex with pyridyl pyrimidine derivative	1.90 Å	2G6P	2G6P	2G6P	2G6P	2G6P	2G6P	Hu et al., 2006
human type 1 methionine aminopeptidase in complex with ovalicin at 1.1 ang	1.10 Å	2GZ5	2GZ5	2GZ5	2GZ5	2GZ5	2GZ5	Addlagatta & Matthews, 2006
complex with 3-tert-butoxycarbonylaminopyridine-2- carboxylic acid thiazole-2-ylamide	1.50 Å	2NQ6	2NQ6	2NQ6	2NQ6	2NQ6	2NQ6	Hu et al., 2006
complex with 3-(2,2-dimethylpropionylamino)pyridine-2- carboxylic acid thiazole-2-ylamide	1.60 Å	2NQ7	2NQ7	2NQ7	2NQ7	2NQ7	2NQ7	Hu et al., 2006
complex with bengamide analog Y16	1.55 Å	4FLI	4FLI	4FLI	4FLI	4FLI	4FLI	Xu et al., 2012
complex with bengamide analog Y08	1.74 Å	4FLJ	4FLJ	4FLJ	4FLJ	4FLJ	4FLJ	Xu et al., 2012
complex with bengamide analog Y10	1.47 Å	4FLK	4FLK	4FLK	4FLK	4FLK	4FLK	Xu et al., 2012
complex with bengamide analog YZ6	1.50 Å	4FLL	4FLL	4FLL	4FLL	4FLL	4FLL	Xu et al., 2012
mature peptidase	2.09 Å	4HXX	4HXX	4HXX	4HXX	4HXX	4HXX	Zhang et al., 2013
mature peptidase	1.78 Å	4IKR	4IKR	4IKR	4IKR	4IKR	4IKR	Kishor et al., 2013
mature peptidase	1.70 Å	4IKS	4IKS	4IKS	4IKS	4IKS	4IKS	Kishor et al., 2013
mature peptidase	1.60 Å	4IKT	4IKT	4IKT	4IKT	4IKT	4IKT	Kishor et al., 2013
mature peptidase	1.30 Å	4IKU	4IKU	4IKU	4IKU	4IKU	4IKU	Kishor et al., 2013
mature peptidase	1.90 Å	4IU6	4IU6	4IU6	4IU6	4IU6	4IU6	Zhang et al., 2013
mature peptidase	1.89 Å	4U1B	4U1B	4U1B	4U1B	4U1B	4U1B	Arya et al., 2015
mature peptidase	1.60 Å	4U69	4U69	4U69	4U69	4U69	4U69	Arya et al., 2015
mature peptidase	1.91 Å	4U6C	4U6C	4U6C	4U6C	4U6C	4U6C	Arya et al., 2015
mature peptidase	1.90 Å	4U6E	4U6E	4U6E	4U6E	4U6E	4U6E	Arya et al., 2015
mature peptidase	1.56 Å	4U6J	4U6J	4U6J	4U6J	4U6J	4U6J	Arya et al., 2015
mature peptidase	1.83 Å	4U6W	4U6W	4U6W	4U6W	4U6W	4U6W	Arya et al., 2015
mature peptidase	1.80 Å	4U6Z	4U6Z	4U6Z	4U6Z	4U6Z	4U6Z	Arya et al., 2015
mature peptidase	1.60 Å	4U70	4U70	4U70	4U70	4U70	4U70	Arya et al., 2015
mature peptidase	1.80 Å	4U71	4U71	4U71	4U71	4U71	4U71	Arya et al., 2015
mature peptidase	1.80 Å	4U73	4U73	4U73	4U73	4U73	4U73	Arya et al., 2015
mature peptidase	1.94 Å	4U75	4U75	4U75	4U75	4U75	4U75	Arya et al., 2015
mature peptidase	1.87 Å	4U76	4U76	4U76	4U76	4U76	4U76	Arya et al., 2015
Phe309Met mutant; complex with ovalicin	1.68 Å	5YKP	5YKP	5YKP	5YKP	5YKP	5YKP
Phe309Met mutant; comlex with tnp470	1.82 Å	5YR4	5YR4	5YR4	5YR4	5YR4	5YR4
Phe309Leu mutant; complex with ovalicin	1.60 Å	5YR5	5YR5	5YR5	5YR5	5YR5	5YR5
Phe309Met mutant; complex with tnp470	1.75 Å	5YR6	5YR6	5YR6	5YR6	5YR6	5YR6
human methionine aminopeptidase type 1b (f309l mutant)	2.06 Å	5YR7	5YR7	5YR7	5YR7	5YR7	5YR7
Plasmodium falciparum
crystal structure of methionine aminopeptidase 1b from plasmodium falciparum, pf10_0150	1.95 Å	3S6B	3S6B	3S6B	3S6B	3S6B	3S6B
Trypanosoma brucei
mature peptidase	1.75 Å	4FUK	4FUK	4FUK	4FUK	4FUK	4FUK