Structure for peptidase C30.004: porcine transmissible gastroenteritis virus-type main peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

PDB Organism Resolution Comment
1LVO_A transmissible gastroenteritis virus 1.96 Å mature
One monomer of the homohexamer is shown. Catalytic residues are shown in ball-and-stick representation: His2919 in purple and Cys3022 in yellow.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
feline infectious peritonitis virus
complex with N-(tert-butoxycarbonyl)-L-seryl-L-valyl-N-(2S)-5-ethoxy-5-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]pentan-2-yl-L-leucinamide inhibitor 2.06 Å 4ZRO 4ZRO 4ZRO 4ZRO 4ZRO 4ZRO St et al., 2015
transmissible gastroenteritis virus
mature  peptidase 1.96 Å 1LVO 1LVO 1LVO 1LVO 1LVO 1LVO Anand et al., 2002
complex with an inhibitor N1 2.70 Å 2AMP 2AMP 2AMP 2AMP 2AMP 2AMP Yang et al., 2005
crystal structure of transmissible gastroenteritis virus papain-like protease 1 2.50 Å 3MP2 3MP2 3MP2 3MP2 3MP2 3MP2
complex with a covalently bound dipeptidyl inhibitor 2.25 Å 4F49 4F49 4F49 4F49 4F49 4F49