Structure for peptidase C03.014: human enterovirus 71 3C peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
human enterovirus 71
human enterovirus 71 3c protease 2.99 Å 3OSY 3OSY 3OSY 3OSY 3OSY 3OSY
Glu71Asp mutant; complex with rupintrivir 1.70 Å 3QZQ 3QZQ 3QZQ 3QZQ 3QZQ 3QZQ
Glu71Ala mutant; complex with rupintrivir 1.04 Å 3QZR 3QZR 3QZR 3QZR 3QZR 3QZR
His133Gly mutant; complex with rupintrivir 1.31 Å 3R0F 3R0F 3R0F 3R0F 3R0F 3R0F
human enterovirus 71 in complex with capsid binding inhibitor win51711 2.70 Å 3ZFE 3ZFE 3ZFE 3ZFE 3ZFE 3ZFE
human enterovirus 71 in complex with capsid binding inhibitor win51711 3.40 Å 3ZFF 3ZFF 3ZFF 3ZFF 3ZFF 3ZFF
human enterovirus 71 in complex with capsid binding inhibitor win51711 3.20 Å 3ZFG 3ZFG 3ZFG 3ZFG 3ZFG 3ZFG
crystal structure of human enterovirus 71 3.80 Å 4AED 4AED 4AED 4AED 4AED 4AED
cryo-em reconstruction of enterovirus 71 in complex with a neutralizing antibody e18 10.00 Å 4C0U 4C0U 4C0U 4C0U 4C0U 4C0U
cryo-em reconstruction of empty enterovirus 71 in complex with a neutralizing antibody e18 16.00 Å 4C0Y 4C0Y 4C0Y 4C0Y 4C0Y 4C0Y
cryo-em reconstruction of empty enterovirus 71 in complex with a neutralizing antibody e19 13.00 Å 4C10 4C10 4C10 4C10 4C10 4C10
crystal structure of human enterovirus 71 in complex with the uncoating inhibitor gpp2 2.65 Å 4CDQ 4CDQ 4CDQ 4CDQ 4CDQ 4CDQ
crystal structure of human enterovirus 71 in complex with the uncoating inhibitor gpp3 2.80 Å 4CDU 4CDU 4CDU 4CDU 4CDU 4CDU
crystal structure of human enterovirus 71 in complex with the uncoating inhibitor gpp4 2.80 Å 4CDW 4CDW 4CDW 4CDW 4CDW 4CDW
crystal structure of human enterovirus 71 in complex with the uncoating inhibitor gpp12 2.80 Å 4CDX 4CDX 4CDX 4CDX 4CDX 4CDX
crystal structure of human enterovirus 71 in complex with the uncoating inhibitor ald 2.75 Å 4CEW 4CEW 4CEW 4CEW 4CEW 4CEW
crystal structure of human enterovirus 71 in complex with the uncoating inhibitor nld 2.75 Å 4CEY 4CEY 4CEY 4CEY 4CEY 4CEY
Cys110Ala mutant 1.90 Å 4FVB 4FVB 4FVB 4FVB 4FVB 4FVB
Cys110Ala mutant; complex with substrate 1.66 Å 4FVD 4FVD 4FVD 4FVD 4FVD 4FVD
mature  peptidase 2.20 Å 4GHQ 4GHQ 4GHQ 4GHQ 4GHQ 4GHQ
complex with ag7088 1.96 Å 4GHT 4GHT 4GHT 4GHT 4GHT 4GHT
human enterovirus 71 uncoating intermediate captured at atomic resolution 3.80 Å 4N43 4N43 4N43 4N43 4N43 4N43
complex with compound xb 1.49 Å 5C1U 5C1U 5C1U 5C1U 5C1U 5C1U
complex with compound viii 1.86 Å 5C1X 5C1X 5C1X 5C1X 5C1X 5C1X
complex with compound 1 1.97 Å 5C1Y 5C1Y 5C1Y 5C1Y 5C1Y 5C1Y
complex with compound 2 2.75 Å 5C20 5C20 5C20 5C20 5C20 5C20
complex with compound 2 2.05 Å 5DP3 5DP3 5DP3 5DP3 5DP3 5DP3
complex with compound 3 2.21 Å 5DP4 5DP4 5DP4 5DP4 5DP4 5DP4
complex with compound 4 2.03 Å 5DP5 5DP5 5DP5 5DP5 5DP5 5DP5
complex with compound 7 3.01 Å 5DP6 5DP6 5DP6 5DP6 5DP6 5DP6
complex with compound 5 2.08 Å 5DP7 5DP7 5DP7 5DP7 5DP7 5DP7
complex with compound 8 2.40 Å 5DP8 5DP8 5DP8 5DP8 5DP8 5DP8
complex with compound 9 1.90 Å 5DP9 5DP9 5DP9 5DP9 5DP9 5DP9
complex with compound 6 2.06 Å 5DPA 5DPA 5DPA 5DPA 5DPA 5DPA
complex with nk-1.8k 2.60 Å 5GSO 5GSO 5GSO 5GSO 5GSO 5GSO
complex with n69s 1.8k 3.19 Å 5GSW 5GSW 5GSW 5GSW 5GSW 5GSW
complex with rupintrivir 1.39 Å 5WQ2 5WQ2 5WQ2 5WQ2 5WQ2 5WQ2
human enterovirus A
cryo-em structure of cva6 vlp 3.00 Å 5YHQ 5YHQ 5YHQ 5YHQ 5YHQ 5YHQ