$VAR1 = undef;

Summary for peptidase C03.014: human enterovirus 71 3C peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namehuman enterovirus 71 3C peptidase
Other namesEV71, human hand, foot and mouth disease virus 3C peptidase
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(C) >> Family C3 >> Subfamily A >> C03.014
Holotypehuman enterovirus 71 3C peptidase, Uniprot accession Q66479 (peptidase unit: 1549-1731), MERNUM MER0004031
History Identifier created: MEROPS 6.7 (29 June 2004)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternA/v/-/QScissile bondGs/-/-/- (based on 10 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 0 0 0 7 3 0 1
Pro 0 0 0 0 0 2 2 1
Ala 8 1 0 0 0 0 0 0
Val 0 3 1 0 0 1 1 1
Leu 0 1 3 0 0 0 0 1
Ile 0 0 1 0 0 0 1 0
Met 0 1 1 0 0 0 0 0
Phe 0 0 1 0 0 1 2 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 1 0
Ser 0 2 0 0 3 1 2 0
Thr 0 2 1 0 0 0 0 1
Cys 1 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 10 0 0 0 1
Asp 0 0 0 0 0 1 0 1
Glu 0 0 2 0 0 1 0 0
Lys 0 0 0 0 0 0 0 1
Arg 0 0 0 0 0 0 1 2
His 0 0 0 0 0 0 0 0