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PDBsum entry 3qzr
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Hydrolase/hydrolase inhibitor
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PDB id
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3qzr
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PDB id:
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| Name: |
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Hydrolase/hydrolase inhibitor
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Title:
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Human enterovirus 71 3c protease mutant e71a in complex with rupintrivir
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Structure:
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3c protein. Chain: a, b. Synonym: 3c protease. Engineered: yes. Mutation: yes
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Source:
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Human enterovirus 71. Organism_taxid: 39054. Strain: 71. Gene: polyprotein. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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1.04Å
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R-factor:
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0.151
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R-free:
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0.164
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Authors:
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J.Wang,T.Fan,X.Yao,Z.Wu,L.Guo,X.Lei,J.Wang,M.Wang,Q.Jin,S.Cui
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Key ref:
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J.Wang
et al.
(2011).
Crystal structures of enterovirus 71 3C protease complexed with rupintrivir reveal the roles of catalytically important residues.
J Virol,
85,
10021-10030.
PubMed id:
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Date:
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07-Mar-11
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Release date:
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10-Aug-11
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PROCHECK
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Headers
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References
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E7E815
(E7E815_HE71) -
Genome polyprotein (Fragment) from Human enterovirus 71
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Seq:
Struc:
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183 a.a.
180 a.a.*
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Key: |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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J Virol
85:10021-10030
(2011)
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PubMed id:
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Crystal structures of enterovirus 71 3C protease complexed with rupintrivir reveal the roles of catalytically important residues.
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J.Wang,
T.Fan,
X.Yao,
Z.Wu,
L.Guo,
X.Lei,
J.Wang,
M.Wang,
Q.Jin,
S.Cui.
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ABSTRACT
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Links
