Structure for peptidase A01.022: plasmepsin-1

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
3QS1 Plasmodium falciparum 3.10 Å complex with KNI-10006 inhibitor
Active site residues are shown in ball-and-stick representation: Asp32 and Asp75 in pink, and Tyr215 in green. KNI-10006 is shown in grey in ball-and-stick representation.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Plasmodium falciparum
theoretical model 0.00 Å 1LCR 1LCR 1LCR 1LCR 1LCR 1LCR
mature  peptidase 0.00 Å 1LDU 1LDU 1LDU 1LDU 1LDU 1LDU
mature  peptidase 2.40 Å 3QRV 3QRV 3QRV 3QRV 3QRV 3QRV Bhaumik et al., 2011
complex with KNI-10006 inhibitor 3.10 Å 3QS1 3QS1 3QS1 3QS1 3QS1 3QS1 Bhaumik et al., 2011