Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P08709

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
20	unknown peptidase	1-466	P		NT	<%Agarwal et al., 2012[]%>
60	unknown peptidase	1-466	P		NT	<%Agarwal et al., 2012[]%>
212	factor VII-activating peptidase	61-466	P		CS	R”misch et al., 1999
212	coagulation factor XIIa	21-466	P			Ratnoff, 2004
212	coagulation factor IXa	21-466	P
212	coagulation factor VIIa	21-466	P			Morrissey, 2004
212	coagulation factor Xa	21-466	P
212	thrombin	21-466	P	conversion to two-chain form
212	hepsin	21-466	P			Kazama et al., 1995