Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P04275

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-2813	P	release of a signal peptide	NT	Shelton-Inloes et al., 1987
763	immune inhibitor A peptidase (Bacillus sp.)	23-2813	N			Chung et al., 2008
763	furin	23-2813	P			<%Wise et al., 1991[]%>
763	PCSK2 peptidase	758-767	N		CS	Remacle et al., 2008
763	PCSK4 peptidase	758-767	N		CS	Remacle et al., 2008
763	PCSK6 peptidase	23-2813	P			Mains, 2004
763	PCSK5 peptidase	758-767	N		CS	Remacle et al., 2008
763	PCSK7 peptidase	758-767	N		CS	Remacle et al., 2008
1471	kaouthiagin	764-2813	N		NT	Hamako et al., 1998
1604	elastase-2	1596-1669	N		MS	Lancellotti et al., 2011
1605	ADAMTS13 peptidase	764-2813	P			Soejima et al., 2001
1605	cathepsin G	764-2813	P		NT	Raife et al., 2009
1606	matrix metallopeptidase-9	764-2813	P		MS	Raife et al., 2009
1607	elastase-2	764-2813	P		NT	Raife et al., 2009
1607	myeloblastin	764-2813	P		NT	Raife et al., 2009
1612	myeloblastin	1596-1669	N		MS	Lancellotti et al., 2011
1626	elastase-2	1596-1669	N		MS	Lancellotti et al., 2011
1628	elastase-2	1596-1669	N		MS	Lancellotti et al., 2011
1642	elastase-2	1596-1669	N		MS	Lancellotti et al., 2011
1647	elastase-2	1596-1669	N		MS	Lancellotti et al., 2011
1649	elastase-2	1596-1669	N		MS	Lancellotti et al., 2011
1651	elastase-2	1596-1669	N		MS	Lancellotti et al., 2011
1664	immune inhibitor A peptidase (Bacillus sp.)	23-2813	N			Chung et al., 2008