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Display Known Cleavages for a Protein

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Accession:

Sequence P01178

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	unknown peptidase	1-125	P	release of a signal peptide	NT	Light & du, 1958
20	cystinyl aminopeptidase	20-28	N			Nomura et al., 2004
23	chymotrypsin C	20-28	N		NT	Folk et al., 1965
26	neprilysin	20-28	P			Johnson et al., 1984
26	prolyl oligopeptidase	20-28	N			Koida & Walter, 1976
27	chymotrypsin C	20-28	N		NT	Folk et al., 1965
27	peptidyl-glycinamidase	20-28	N			Simmons, 2004
31	magnolysin	20-125	P			Rholam et al., 2004
31	dibasic processing endopeptidase (unsequenced)	20-125	P		NT	Brakch et al., 1989