Substrates for peptidase S9F.001: peptidyl-glycinamidase

Summary Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ac-Tyr-OEt [ATEE] Ac-Tyr+OEt S - - Ac Tyr OEt - - - Simmons, 2004
Bz-Arg-OEt [BAEE] Bz-Arg+OEt S - - Bz Arg OEt - - - Simmons, 2004
oxytocin P01178 20-28 Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu+Gly-NH2 N Asn Cys Pro Leu Gly NH2 - - Simmons, 2004
substance P P20366 58-68 Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu+Met-NH2 N Phe Phe Gly Leu Met NH2 - - Simmons, 2004
vasopressin-neurophysin 2-copeptin P01186 24-32 Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg+Gly-NH2 N Asn Cys Pro Arg Gly NH2 - - Simmons, 2004