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author:"Bushell SR"

Filter By

Current Database

  • EMDB [12]

Current status

  • REL [12]

Sample type

  • Protein [12]
  • Ligand [10]
  • Complex [7]
  • Cellular component [5]

Organism

  • Homo sapiens [12]
  • Lama glama [1]

EM Method

  • Single-particle [12]

Resolution

  • ≥ 3Å and < 4Å [9]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [5]
  • 250-500 kDa [6]

Release Date

  • 2024 [7]
  • 2019 [5]

Author by name

  • Bushell SR [12]
  • Carpenter EP [12]
  • Pike ACW [12]
  • Burgess-brown NA [11]
  • Shrestha L [9]
  • Bountra C [8]
  • Rodstrom KEJ [7]
  • Chalk R [6]
  • Chi G [6]
  • Dafforn TR [6]
  • Evans A [6]
  • Hansen JS [6]
  • He D [6]
  • Lee SC [6]
  • Lee SG [6]
  • Li HZ [6]
  • Lotsaris I [6]
  • Maclean EM [6]
  • Marsden B [6]
  • Moreira T [6]
  • Nasrallah C [6]
  • Sauer DB [6]
  • Speedman D [6]
  • Vandenberg RJ [6]
  • Wang D [6]
  • Huiskonen JT [5]
  • Shintre CA [5]
  • Tessitore A [5]
  • Accardi A [3]
  • Christianson JC [3]
  • Chu A [3]
  • Corey RA [3]
  • Falzone ME [3]
  • Love JD [3]
  • Mukhopadhyay SMM [3]
  • Newport TD [3]
  • Rorsman NJG [3]
  • Scofano LF [3]
  • Sitsapesan R [3]
  • Stansfeld PJ [3]
  • Ta CM [3]
  • Tammaro P [3]
  • Wang Q [3]
  • Arrowsmith CH [2]
  • Edwards AM [2]
  • Mukhopadhyay S [2]
  • Strain-damerell C [2]
  • Young M [2]
  • Ang J [1]
  • Baronina A [1]
  • Baukrowitz T [1]
  • Cloake A [1]
  • Elliott J [1]
  • Holland-kaye I [1]
  • Newstead S [1]
  • Owens RJ [1]
  • Pardon E [1]
  • Proks P [1]
  • Schewe M [1]
  • Smith KHM [1]
  • Sormann J [1]
  • Steyaert J [1]
  • Tucker SJ [1]

Author by ORCID

  • Pike ACW [9]
  • Lotsaris I [6]
  • Sauer DB [6]
  • Chi G [6]
  • Li HZ [6]
  • Wang D [6]
  • Vandenberg RJ [6]
  • Speedman D [6]
  • Bushell SR [3]
  • Falzone ME [3]
  • Shintre CA [3]
  • Stansfeld PJ [3]
  • Carpenter EP [3]
  • Huiskonen JT [3]
  • Christianson JC [3]
  • Scofano LF [3]
  • Tammaro P [3]
  • Accardi A [3]
  • Mukhopadhyay SMM [3]
  • Corey RA [3]
  • Chu A [3]
  • Steyaert J [1]
  • Tucker SJ [1]
  • Ang J [1]
  • Baukrowitz T [1]
  • Pike ACW [1]
  • Sormann J [1]
  • Elliott J [1]
  • Pardon E [1]
  • Newstead S [1]
  • Carpenter EP [1]
  • Holland-kaye I [1]
  • Schewe M [1]
  • Smith KHM [1]
  • Owens RJ [1]

Journal

  • NAT COMMUN [10]
  • TO BE PUBLISHED [2]

Software

  • CRYOSPARC [9]
  • RELION [7]
  • COOT [1]
  • CTFFIND [1]

Microscope

  • FEI TITAN KRIOS [11]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [12]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [8]
  • GATAN K3 BIOQUANTUM 6K X 4K [3]
  • FEI FALCON IV 4K X 4K [1]

External links

  • AlphaFold DB [12]
  • PDBe-Kb [12]
  • UniProt [12]
  • Gene Ontology [11]
  • InterPro [11]
  • PDB [11]
  • Pfam [11]
  • ChEBI [10]
  • DrugBank [8]
  • ChEMBL [7]
Sort by: Download
Showing 1 - 10 of 12. Page 1 of 2
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EMD-17377
Download Map
3D View
Structure of human SIT1 focussed map / refinement
Release date: June 12, 2024
Resolution: 3.76 Å
EM Method: Single-particle
Fitted PDBs: 8p2w
Q-score: 0.408

Li HZ, Pike ACW, Lotsaris I, Chi G, Hansen JS, Lee SC, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Burgess-Brown NA, Vandenberg RJ, Dafforn TR, Carpenter EP, Sauer DB

Nat Commun (2024) 15 pp. 5503-5503 [ DOI: doi:10.1038/s41467-024-48921-x Pubmed: 38951531 ]

EMD-17378
Download Map
3D View
Structure of human SIT1:ACE2 complex open PD conformation
Release date: June 12, 2024
Resolution: 3.59 Å
EM Method: Single-particle
Fitted PDBs: 8p2x
Q-score: 0.361

Li HZ, Pike ACW, Lotsaris I, Chi G, Hansen JS, Lee SC, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Burgess-Brown NA, Vandenberg RJ, Dafforn TR, Carpenter EP, Sauer DB

Nat Commun (2024) 15 pp. 5503-5503 [ DOI: doi:10.1038/s41467-024-48921-x Pubmed: 38951531 ]

EMD-17379
Download Map
3D View
Structure of human SIT1:ACE2 complex closed PD conformation
Release date: June 12, 2024
Resolution: 3.46 Å
EM Method: Single-particle
Fitted PDBs: 8p2y
Q-score: 0.368

Li HZ, Pike ACW, Lotsaris I, Chi G, Hansen JS, Lee SC, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Burgess-Brown NA, Vandenberg RJ, Dafforn TR, Carpenter EP, Sauer DB

Nat Commun (2024) 15 pp. 5503-5503 [ DOI: doi:10.1038/s41467-024-48921-x Pubmed: 38951531 ]

EMD-17380
Download Map
3D View
Structure of human SIT1 bound to L-pipecolate focussed map / refinement
Release date: June 12, 2024
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8p2z
Q-score: 0.481

Li HZ, Pike ACW, Lotsaris I, Chi G, Hansen JS, Lee SC, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Burgess-Brown NA, Vandenberg RJ, Dafforn TR, Carpenter EP, Sauer DB

Nat Commun (2024) 15 pp. 5503-5503 [ DOI: doi:10.1038/s41467-024-48921-x Pubmed: 38951531 ]

EMD-17381
Download Map
3D View
Structure of human SIT1:ACE2 complex open PD conformation bound to L-pipecolate
Release date: June 12, 2024
Resolution: 3.29 Å
EM Method: Single-particle
Fitted PDBs: 8p30
Q-score: 0.414

Li HZ, Pike ACW, Lotsaris I, Chi G, Hansen JS, Lee SC, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Burgess-Brown NA, Vandenberg RJ, Dafforn TR, Carpenter EP, Sauer DB

Nat Commun (2024) 15 pp. 5503-5503 [ DOI: doi:10.1038/s41467-024-48921-x Pubmed: 38951531 ]

EMD-17382
Download Map
3D View
Structure of human SIT1:ACE2 complex closed PD conformation bound to L-pipecolate
Release date: June 12, 2024
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 8p31
Q-score: 0.415

Li HZ, Pike ACW, Lotsaris I, Chi G, Hansen JS, Lee SC, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Burgess-Brown NA, Vandenberg RJ, Dafforn TR, Carpenter EP, Sauer DB

Nat Commun (2024) 15 pp. 5503-5503 [ DOI: doi:10.1038/s41467-024-48921-x Pubmed: 38951531 ]

EMD-19066
Download Map
3D View
TREK2 in OGNG/CHS detergent micelle with biparatopic inhibitory nanobody Nb6158
Release date: May 29, 2024
Resolution: 7.37 Å
EM Method: Single-particle

Rodstrom KEJ, Cloake A, Sormann J, Baronina A, Smith KHM, Pike ACW, Ang J, Proks P, Schewe M, Holland-Kaye I, Bushell SR, Elliott J, Pardon E, Baukrowitz T, Owens RJ, Newstead S, Steyaert J, Carpenter EP, Tucker SJ

Nat Commun (2024) 15 pp. 4173-4173 [ DOI: doi:10.1038/s41467-024-48536-2 Pubmed: 38755204 ]

EMD-0093
Download Map
3D View
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
Release date: May 8, 2019
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6gyn
Q-score: 0.479

Shintre CA, Pike ACW, Tessitore A, Young M, Bushell SR, Strain-Damerell C, Mukhopadhyay S, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP

To Be Published

EMD-0094
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3D View
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Release date: May 1, 2019
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6gyo
Q-score: 0.502

Shintre CA, Pike ACW, Tessitore A, Young M, Bushell SR, Strain-Damerell C, Mukhopadhyay S, Burgess-Brown NA, Huiskonen JT, Arrowsmith CH, Edwards AM, Bountra C, Carpenter EP

To Be Published

EMD-4746
Download Map
3D View
CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent 2mM Ca2 , closed form
Release date: May 1, 2019
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 6r7x
Q-score: 0.516

Bushell SR, Pike ACW, Falzone ME, Rorsman NJG, Ta CM, Corey RA, Newport TD, Christianson JC, Scofano LF, Shintre CA, Tessitore A, Chu A, Wang Q, Shrestha L, Mukhopadhyay SMM, Love JD, Burgess-Brown NA, Sitsapesan R, Stansfeld PJ, Huiskonen JT, Tammaro P, Accardi A, Carpenter EP

Nat Commun (2019) 10 pp. 3956-3956 [ Pubmed: 31477691 DOI: doi:10.1038/s41467-019-11753-1 ]

Sort by: Download
Showing 1 - 10 of 12. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [12]

Current status

  • REL [12]

Sample type

  • Protein [12]
  • Ligand [10]
  • Complex [7]
  • Cellular component [5]

Organism

  • Homo sapiens [12]
  • Lama glama [1]

EM Method

  • Single-particle [12]

Resolution

  • ≥ 3Å and < 4Å [9]
  • ≥ 4Å and < 5Å [1]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [5]
  • 250-500 kDa [6]

Release Date

  • 2024 [7]
  • 2019 [5]

Author by name

  • Bushell SR [12]
  • Carpenter EP [12]
  • Pike ACW [12]
  • Burgess-brown NA [11]
  • Shrestha L [9]
  • Bountra C [8]
  • Rodstrom KEJ [7]
  • Chalk R [6]
  • Chi G [6]
  • Dafforn TR [6]
  • Evans A [6]
  • Hansen JS [6]
  • He D [6]
  • Lee SC [6]
  • Lee SG [6]
  • Li HZ [6]
  • Lotsaris I [6]
  • Maclean EM [6]
  • Marsden B [6]
  • Moreira T [6]
  • Nasrallah C [6]
  • Sauer DB [6]
  • Speedman D [6]
  • Vandenberg RJ [6]
  • Wang D [6]
  • Huiskonen JT [5]
  • Shintre CA [5]
  • Tessitore A [5]
  • Accardi A [3]
  • Christianson JC [3]
  • Chu A [3]
  • Corey RA [3]
  • Falzone ME [3]
  • Love JD [3]
  • Mukhopadhyay SMM [3]
  • Newport TD [3]
  • Rorsman NJG [3]
  • Scofano LF [3]
  • Sitsapesan R [3]
  • Stansfeld PJ [3]
  • Ta CM [3]
  • Tammaro P [3]
  • Wang Q [3]
  • Arrowsmith CH [2]
  • Edwards AM [2]
  • Mukhopadhyay S [2]
  • Strain-damerell C [2]
  • Young M [2]
  • Ang J [1]
  • Baronina A [1]
  • Baukrowitz T [1]
  • Cloake A [1]
  • Elliott J [1]
  • Holland-kaye I [1]
  • Newstead S [1]
  • Owens RJ [1]
  • Pardon E [1]
  • Proks P [1]
  • Schewe M [1]
  • Smith KHM [1]
  • Sormann J [1]
  • Steyaert J [1]
  • Tucker SJ [1]

Author by ORCID

  • Pike ACW [9]
  • Lotsaris I [6]
  • Sauer DB [6]
  • Chi G [6]
  • Li HZ [6]
  • Wang D [6]
  • Vandenberg RJ [6]
  • Speedman D [6]
  • Bushell SR [3]
  • Falzone ME [3]
  • Shintre CA [3]
  • Stansfeld PJ [3]
  • Carpenter EP [3]
  • Huiskonen JT [3]
  • Christianson JC [3]
  • Scofano LF [3]
  • Tammaro P [3]
  • Accardi A [3]
  • Mukhopadhyay SMM [3]
  • Corey RA [3]
  • Chu A [3]
  • Steyaert J [1]
  • Tucker SJ [1]
  • Ang J [1]
  • Baukrowitz T [1]
  • Pike ACW [1]
  • Sormann J [1]
  • Elliott J [1]
  • Pardon E [1]
  • Newstead S [1]
  • Carpenter EP [1]
  • Holland-kaye I [1]
  • Schewe M [1]
  • Smith KHM [1]
  • Owens RJ [1]

Journal

  • NAT COMMUN [10]
  • TO BE PUBLISHED [2]

Software

  • CRYOSPARC [9]
  • RELION [7]
  • COOT [1]
  • CTFFIND [1]

Microscope

  • FEI TITAN KRIOS [11]
  • FEI TALOS ARCTICA [1]

Electron Source

  • FIELD EMISSION GUN [12]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [8]
  • GATAN K3 BIOQUANTUM 6K X 4K [3]
  • FEI FALCON IV 4K X 4K [1]

External links

  • AlphaFold DB [12]
  • PDBe-Kb [12]
  • UniProt [12]
  • Gene Ontology [11]
  • InterPro [11]
  • PDB [11]
  • Pfam [11]
  • ChEBI [10]
  • DrugBank [8]
  • ChEMBL [7]