EMD-17378

Single-particle
3.59 Å
EMD-17378
3D View Gallery
Deposition: 16/05/2023
Map released: 12/06/2024
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17378

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8p2x summary report (pdf.gz) Map-8p2x FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human SIT1:ACE2 complex (open PD conformation)

EMD-17378

Single-particle
3.59 Å
EMD-17378
3D View Gallery
Deposition: 16/05/2023
Map released: 12/06/2024
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: SIT1:ACE2 complex
Fitted models: 8p2x

Deposition Authors: Li HZ, Pike ACW , Chi G , Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D , Evans A, Wang D , He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB
Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2.
Li HZ, Pike ACW , Lotsaris I , Chi G , Hansen JS, Lee SC, Rodstrom KEJ, Bushell SR, Speedman D , Evans A, Wang D , He D, Shrestha L, Nasrallah C, Burgess-Brown NA, Vandenberg RJ , Dafforn TR, Carpenter EP, Sauer DB
(2024) Nat Commun , 15 , 5503 - 5503
PUBMED: 38951531
DOI: doi:10.1038/s41467-024-48921-x
ISSN: 2041-1723
Grant Support: