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EMD-17381
Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate
EMD-17381
Single-particle3.29 Å
Deposition: 16/05/2023Map released: 12/06/2024
Last modified: 20/11/2024
Sample Organism:
Homo sapiens
Sample: SIT1:ACE2 complex
Fitted models: 8p30
Deposition Authors: Li HZ, Pike ACW
,
Chi G
,
Hansen JS,
Lee SG,
Rodstrom KEJ,
Bushell SR,
Speedman D
,
Evans A,
Wang D
,
He D,
Shrestha L,
Nasrallah C,
Chalk R,
Moreira T,
MacLean EM,
Marsden B,
Bountra C,
Burgess-Brown NA,
Dafforn TR,
Carpenter EP,
Sauer DB
Sample: SIT1:ACE2 complex
Fitted models: 8p30
Deposition Authors: Li HZ, Pike ACW
,
Chi G
,
Hansen JS,
Lee SG,
Rodstrom KEJ,
Bushell SR,
Speedman D
,
Evans A,
Wang D
,
He D,
Shrestha L,
Nasrallah C,
Chalk R,
Moreira T,
MacLean EM,
Marsden B,
Bountra C,
Burgess-Brown NA,
Dafforn TR,
Carpenter EP,
Sauer DB
Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2.
Li HZ,
Pike ACW
,
Lotsaris I
,
Chi G
,
Hansen JS,
Lee SC,
Rodstrom KEJ,
Bushell SR,
Speedman D
,
Evans A,
Wang D
,
He D,
Shrestha L,
Nasrallah C,
Burgess-Brown NA,
Vandenberg RJ
,
Dafforn TR,
Carpenter EP,
Sauer DB
(2024) Nat Commun , 15 , 5503 - 5503
,
Lotsaris I
,
Chi G
,
Hansen JS,
Lee SC,
Rodstrom KEJ,
Bushell SR,
Speedman D
,
Evans A,
Wang D
,
He D,
Shrestha L,
Nasrallah C,
Burgess-Brown NA,
Vandenberg RJ
,
Dafforn TR,
Carpenter EP,
Sauer DB
(2024) Nat Commun , 15 , 5503 - 5503
Grant Support:
- UK Research and Innovation (UKRI): BB/V018051/1 (United Kingdom)
