Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-4746
CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form)
EMD-4746
Single-particle3.47 Å
Deposition: 29/03/2019Map released: 01/05/2019
Last modified: 22/05/2024
Sample Organism:
Homo sapiens
Sample: Anoctamin 10
Fitted models: 6r7x
Deposition Authors: Pike ACW
,
Bushell SR
Sample: Anoctamin 10
Fitted models: 6r7x
Deposition Authors: Pike ACW
,
Bushell SR
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Bushell SR ,
Pike ACW ,
Falzone ME ,
Rorsman NJG,
Ta CM,
Corey RA ,
Newport TD,
Christianson JC ,
Scofano LF ,
Shintre CA ,
Tessitore A,
Chu A ,
Wang Q,
Shrestha L,
Mukhopadhyay SMM ,
Love JD,
Burgess-Brown NA,
Sitsapesan R,
Stansfeld PJ ,
Huiskonen JT ,
Tammaro P ,
Accardi A ,
Carpenter EP
(2019) Nat Commun , 10 , 3956 - 3956
,
Pike ACW ,
Falzone ME ,
Rorsman NJG,
Ta CM,
Corey RA ,
Newport TD,
Christianson JC ,
Scofano LF ,
Shintre CA ,
Tessitore A,
Chu A ,
Wang Q,
Shrestha L,
Mukhopadhyay SMM ,
Love JD,
Burgess-Brown NA,
Sitsapesan R,
Stansfeld PJ ,
Huiskonen JT ,
Tammaro P ,
Accardi A ,
Carpenter EP
(2019) Nat Commun , 10 , 3956 - 3956
Grant Support:
- Wellcome Trust: 106169/Z/14/Z (United Kingdom)
- European Commission: 115766 (United Kingdom)