Electron Microscopy
3.47Å resolution

CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form)


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Anoctamin-10 Chains: A, B
Molecule details ›
Chains: A, B
Length: 667 amino acids
Theoretical weight: 77.28 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: Q9NW15 (Residues: 1-660; Coverage: 100%)
Gene names: ANO10, TMEM16K
Sequence domains: Calcium-activated chloride channel

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.47Å
Relevant EMDB volumes: EMD-4746
Expression system: Spodoptera frugiperda