Structure analysis

Structure of the translating mammalian ribosome-Sec61 complex

Electron Microscopy
3.9Å resolution
Source organism: Sus scrofa
Assembly composition:
hetero 86-mer (preferred)
Entry contents: 79 distinct polypeptide molecules
7 distinct RNA molecules

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero 86-mer
PDBe Complex ID: PDB-CPX-236683

Macromolecules

Search similar proteins

Search similar proteins

Chain: D
Length: 297 amino acids
Theoretical weight: 34.42 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A287ASD0 (Residues: 1-297; Coverage: 100%)
Gene name: RPL5
Pfam:
InterPro:

Search similar proteins

Search similar proteins

Search similar proteins

Search similar proteins

Search similar proteins

Search similar proteins

Chain: L
Length: 211 amino acids
Theoretical weight: 24.37 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A4X1TBV3 (Residues: 218-428; Coverage: 49%)
Gene name: RPL13
Pfam: Ribosomal protein L13e
InterPro:

Search similar proteins

Search similar proteins

Chain: N
Length: 204 amino acids
Theoretical weight: 24.21 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A286ZL65 (Residues: 1-204; Coverage: 100%)
Gene name: RPL15
Pfam: Ribosomal L15
InterPro:

Search similar proteins

Search similar proteins

Chain: P
Length: 153 amino acids
Theoretical weight: 17.76 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A287B386 (Residues: 2-154; Coverage: 82%)
Gene name: RPL17
Pfam: Ribosomal protein L22p/L17e
InterPro:

Search similar proteins

Chain: Q
Length: 188 amino acids
Theoretical weight: 21.59 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A4X1W0N5 (Residues: 1-188; Coverage: 100%)
Gene name: RPL18
Pfam: Ribosomal protein 60S L18 and 50S L18e
InterPro:

Search similar proteins

Chain: S
Length: 224 amino acids
Theoretical weight: 26.1 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A287APR1 (Residues: 1-224; Coverage: 100%)
Gene name: RPL18A
Pfam: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
InterPro:

Search similar proteins

Chain: T
Length: 160 amino acids
Theoretical weight: 18.61 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P49666 (Residues: 1-160; Coverage: 100%)
Gene name: RPL21
Pfam: Ribosomal protein L21e
InterPro:

Search similar proteins

Chain: U
Length: 128 amino acids
Theoretical weight: 14.78 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P67985 (Residues: 1-128; Coverage: 100%)
Gene name: RPL22
Pfam: Ribosomal L22e protein family
InterPro:

Search similar proteins

Search similar proteins

Chain: W
Length: 157 amino acids
Theoretical weight: 17.83 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A4X1SH42 (Residues: 1-157; Coverage: 100%)
Gene name: RPL24
Pfam: Ribosomal protein L24e
InterPro:

Search similar proteins

Search similar proteins

Search similar proteins

Search similar proteins

Chain: b
Length: 160 amino acids
Theoretical weight: 17.55 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q95281 (Residues: 1-160; Coverage: 100%)
Gene name: RPL29
Pfam: Ribosomal L29e protein family
InterPro: Large ribosomal subunit protein eL29

Search similar proteins

Search similar proteins

Chain: d
Length: 125 amino acids
Theoretical weight: 14.49 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P62901 (Residues: 1-125; Coverage: 100%)
Gene name: RPL31
Pfam: Ribosomal protein L31e
InterPro:

Search similar proteins

Chain: e
Length: 135 amino acids
Theoretical weight: 15.9 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q6QAT0 (Residues: 1-135; Coverage: 100%)
Gene name: RPL32
Pfam: Ribosomal protein L32
InterPro:

Search similar proteins

Chain: g
Length: 117 amino acids
Theoretical weight: 13.33 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q29223 (Residues: 1-117; Coverage: 100%)
Gene name: RPL34
Pfam: Ribosomal protein L34e
InterPro:

Search similar proteins

Chain: h
Length: 123 amino acids
Theoretical weight: 14.59 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q29361 (Residues: 1-123; Coverage: 100%)
Gene name: RPL35
Pfam: Ribosomal L29 protein
InterPro:

Search similar proteins

Chain: i
Length: 105 amino acids
Theoretical weight: 12.29 KDa
Source organism: Sus scrofa
InterPro:

Search similar proteins

Chain: k
Length: 70 amino acids
Theoretical weight: 8.24 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A4X1VLH7 (Residues: 1-70; Coverage: 100%)
Pfam: Ribosomal L38e protein family
InterPro:

Search similar proteins

Chain: m
Length: 128 amino acids
Theoretical weight: 14.76 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P63053 (Residues: 1-128; Coverage: 100%)
Gene names: UBA52, UBCEP2
Pfam:
InterPro:

Search similar proteins

Chain: o
Length: 106 amino acids
Theoretical weight: 12.48 KDa
Source organism: Sus scrofa
InterPro:

Search similar proteins

Chain: p
Length: 91 amino acids
Theoretical weight: 10.17 KDa
Source organism: Sus scrofa
InterPro:

Search similar proteins

Chain: r
Length: 125 amino acids
Theoretical weight: 14.3 KDa
Source organism: Sus scrofa
InterPro:

Search similar proteins

Search similar proteins

Chain: 1
Length: 393 amino acids
Theoretical weight: 43.5 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A4X1TV07 (Residues: 25-466; Coverage: 83%)
Gene name: SEC61A1
Pfam:
InterPro:

Search similar proteins

Chain: 3
Length: 36 amino acids
Theoretical weight: 3.08 KDa
Source organism: Sus scrofa

Search similar proteins

Search similar proteins

Chain: SB
Length: 264 amino acids
Theoretical weight: 29.93 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: B6V8C8 (Residues: 1-264; Coverage: 100%)
Gene name: RPS3A
Pfam: Ribosomal S3Ae family
InterPro:

Search similar proteins

Search similar proteins

Search similar proteins

Search similar proteins

Chain: SG
Length: 249 amino acids
Theoretical weight: 28.75 KDa
Source organism: Sus scrofa
InterPro:

Search similar proteins

Chain: SH
Length: 194 amino acids
Theoretical weight: 22.17 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A287A9Y6 (Residues: 1-194; Coverage: 100%)
Gene name: RPS7
Pfam: Ribosomal protein S7e
InterPro:

Search similar proteins

Search similar proteins

Search similar proteins

Chain: SK
Length: 165 amino acids
Theoretical weight: 18.97 KDa
Source organism: Sus scrofa
InterPro:

Search similar proteins

Chain: SM
Length: 124 amino acids
Theoretical weight: 13.78 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P46405 (Residues: 9-132; Coverage: 94%)
Gene name: RPS12
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:

Search similar proteins

Search similar proteins

Search similar proteins

Chain: SP
Length: 145 amino acids
Theoretical weight: 17.08 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P62844 (Residues: 1-145; Coverage: 100%)
Gene names: RIG, RPS15
Pfam: Ribosomal protein S19
InterPro:

Search similar proteins

Chain: SQ
Length: 146 amino acids
Theoretical weight: 16.48 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q29201 (Residues: 1-146; Coverage: 100%)
Gene name: RPS16
Pfam: Ribosomal protein S9/S16
InterPro:

Search similar proteins

Chain: SR
Length: 135 amino acids
Theoretical weight: 15.55 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q6QAP7 (Residues: 1-135; Coverage: 100%)
Gene name: RPS17
Pfam: Ribosomal S17
InterPro:

Search similar proteins

Chain: SS
Length: 152 amino acids
Theoretical weight: 17.76 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P62272 (Residues: 1-152; Coverage: 100%)
Gene name: RPS18
Pfam: Ribosomal protein S13/S18
InterPro:

Search similar proteins

Chain: ST
Length: 145 amino acids
Theoretical weight: 16.09 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A4X1SDD8 (Residues: 106-250; Coverage: 58%)
Pfam: Ribosomal protein S19e
InterPro:

Search similar proteins

Search similar proteins

Chain: SV
Length: 83 amino acids
Theoretical weight: 9.12 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P63221 (Residues: 1-83; Coverage: 100%)
Gene name: RPS21
Pfam: Ribosomal protein S21e
InterPro:

Search similar proteins

Search similar proteins

Chain: SX
Length: 143 amino acids
Theoretical weight: 15.85 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q6SA96 (Residues: 1-143; Coverage: 100%)
Gene name: RPS23
Pfam: Ribosomal protein S12/S23
InterPro:

Search similar proteins

Chain: SY
Length: 132 amino acids
Theoretical weight: 15.37 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A4X1SJK8 (Residues: 1-132; Coverage: 100%)
Gene name: RPS24
Pfam: Ribosomal protein S24e
InterPro:

Search similar proteins

Chain: SZ
Length: 125 amino acids
Theoretical weight: 13.78 KDa
Source organism: Sus scrofa
InterPro:

Search similar proteins

Chain: Sa
Length: 115 amino acids
Theoretical weight: 13.05 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P49171 (Residues: 1-115; Coverage: 100%)
Gene name: RPS26
Pfam: Ribosomal protein S26e
InterPro:

Search similar proteins

Chain: Sb
Length: 84 amino acids
Theoretical weight: 9.48 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: A0A4X1W2B6 (Residues: 1-84; Coverage: 100%)
Gene name: RPS27
Pfam: Ribosomal protein S27
InterPro:

Search similar proteins

Chain: Sc
Length: 69 amino acids
Theoretical weight: 7.86 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: Q6QAT1 (Residues: 1-69; Coverage: 100%)
Gene name: RPS28
Pfam: Ribosomal protein S28e
InterPro:

Search similar proteins

Search similar proteins

Search similar proteins

Chain: Sg
Length: 317 amino acids
Theoretical weight: 35.12 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P63246 (Residues: 1-317; Coverage: 100%)
Gene names: GNB2L1, RACK1
Pfam: WD domain, G-beta repeat
InterPro:

Search similar proteins

Name: 28S ribosomal RNA
Representative chains: 5
Length: 3722 nucleotides
Theoretical weight: 1206.1 KDa
Rfam: Eukaryotic large subunit ribosomal RNA

Search similar RNA

Name: 5S ribosomal RNA
Representative chains: 7
Length: 120 nucleotides
Theoretical weight: 38.69 KDa
Rfam: 5S ribosomal RNA

Search similar RNA

Name: 5.8S ribosomal RNA
Representative chains: 8
Length: 156 nucleotides
Theoretical weight: 50.14 KDa
Rfam: 5.8S ribosomal RNA

Search similar RNA

Name: 18S Ribosomal RNA
Representative chains: S2
Length: 1742 nucleotides
Theoretical weight: 561.96 KDa
Rfam: Eukaryotic small subunit ribosomal RNA

Search similar RNA

Name: Messenger RNA
Representative chains: S4
Length: 10 nucleotides
Theoretical weight: 3.04 KDa

Search similar RNA

Name: A/P tRNA
Representative chains: S5
Length: 74 nucleotides
Theoretical weight: 23.87 KDa
Rfam: tRNA

Search similar RNA

Name: P/E tRNA
Representative chains: S6
Length: 76 nucleotides
Theoretical weight: 24.48 KDa
Rfam: tRNA

Search similar RNA