Homologous Superfamily

WD40/YVTN repeat-like-containing domain superfamily (IPR015943)

Short name: WD40/YVTN_repeat-like_dom_sf

Overlapping entries



This superfamily represents a WD40/YVTN repeat-like domain. Both the WD40 and the YVTN repeated motifs consist of about 40 residues, and although they consist of distinct sequences, they do share a similar structure. Structurally, both the WD40 and the YVTN repeated motifs form seven-bladed propellers (although some members can contain eight blades), which consist of seven 4-stranded beta-sheets.

The WD40-type repeat domain is found in the beta-1 subunit of the signal-transducing G protein [PMID: 10360181], in yeast Tup1 protein [PMID: 10856245], in Groucho [PMID: 12057191], in the yeast cell cycle protein Cdc4 [PMID: 12553912] and in actin-interacting protein 1 [PMID: 15150269].

The YVTN-type repeat domain is found in archaeal surface layer proteins (SLPs) that protect cells from extreme environments [PMID: 12377130], in quinohemoprotein amine dehydrogenase (QHNDH) [PMID: 12925784], and in methylamine dehydrogenase [PMID: 9514722].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005515 protein binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.