Substrates for peptidase S01.132: mannan-binding lectin-associated serine peptidase-3

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
ES008 (Z-Leu-Arg-NHMec) Z-Leu-Arg+NHMec S - Z Leu Arg AMC - - - Cortesio & Jiang, 2006
ES009 (Z-Phe-Arg-NHMec) Z-Phe-Arg+NHMec S - Z Phe Arg AMC - - - Cortesio & Jiang, 2006
ES011 (Boc-Val-Pro-Arg-NHMec) Boc-Val-Pro-Arg+NHMec S Boc Val Pro Arg AMC - - - Cortesio & Jiang, 2006
I-1140 (Z-Gly-Gly-Arg-NHMec) Z-Gly-Gly-Arg+NHMec S Z Gly Gly Arg AMC - - - Cortesio & Jiang, 2006
I-1295 (Pro-Phe-Arg-NHMec) Pro-Phe-Arg+NHMec S - Pro Phe Arg AMC - - - Cortesio & Jiang, 2006
insulin-like growth factor binding protein 5 P24593 21-272 peptide-Arg176+Ile-peptide P Ala His Pro Arg Ile Ile Ser Ala Cortesio & Jiang, 2006 20378
insulin-like growth factor binding protein 5 P24593 21-272 peptide-Lys135+Ile-peptide P Tyr Ser Pro Lys Ile Phe Arg Pro Cortesio & Jiang, 2006 20379
insulin-like growth factor binding protein 5 P24593 21-272 peptide-Lys140+His-peptide P Phe Arg Pro Lys His Thr Arg Ile Cortesio & Jiang, 2006 20380