Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P24593

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
20	unknown peptidase	1-272	P		NT	<%Agarwal et al., 2012[]%>
22	calpain-1	21-272	P			Ghosh et al., 2005
27	kallikrein-related peptidase 5	21-272	P		NT	Michael et al., 2006
114	peptidyl-Asp metallopeptidase	21-272	P			Kalus et al., 1998
135	mannan-binding lectin-associated serine peptidase-3	21-272	P			Cortesio & Jiang, 2006
140	mannan-binding lectin-associated serine peptidase-3	21-272	P			Cortesio & Jiang, 2006
140	thrombin	21-272	P			Zheng et al., 1998
143	kallikrein-related peptidase 5	21-272	P		NT	Michael et al., 2006
154	peptidyl-Asp metallopeptidase	21-272	P			Kalus et al., 1998
161	calpain-1	21-272	P			Ghosh et al., 2005
163	pappalysin-1	21-272	P			Laursen et al., 2001
163	pappalysin-2	21-272	P			Overgaard et al., 2001
164	pappalysin-1	21-272	P			Laursen et al., 2001
172	calpain-1	21-272	P			Ghosh et al., 2005
176	mannan-binding lectin-associated serine peptidase-3	21-272	P			Cortesio & Jiang, 2006
176	thrombin	21-272	P			Zheng et al., 1998
212	kallikrein-related peptidase 5	21-272	P		NT	Michael et al., 2006
212	thrombin	21-272	P			Zheng et al., 1998